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Murcko scaffold

Ring system with 3 rings and 17 atoms

187 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
187
With full pages
33
Scaffold SMILES

O=C(c1ccccc1)N1CCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 187 chemicals

(2-Bromo-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone chemical structure, C17H16BrNO3, CAS 65367-71-7
(2-Bromo-4,5-dimethoxyphenyl)(2,3-dihydro-1H-indol-1-yl)methanone
CAS 65367-71-7C17H16BrNO3
1-Benzoyl-3-methyl-2-indolinol chemical structure, C16H15NO2, CAS 22397-26-8
1-Benzoyl-3-methyl-2-indolinol
CAS 22397-26-8C16H15NO2
1-Benzoyl-2-indolinol chemical structure, C15H13NO2, CAS 22397-24-6
1-Benzoyl-2-indolinol
CAS 22397-24-6C15H13NO2
(2,3-Dihydro-1H-indol-1-yl)(2-methylphenyl)methanone chemical structure, C16H15NO, CAS 315248-40-9
(2,3-Dihydro-1H-indol-1-yl)(2-methylphenyl)methanone
CAS 315248-40-9C16H15NO
2-(2,3-Dihydro-1H-indol-1-ylcarbonyl)benzoic acid chemical structure, C16H13NO3, CAS 860614-64-8
2-(2,3-Dihydro-1H-indol-1-ylcarbonyl)benzoic acid
CAS 860614-64-8C16H13NO3
(2-Aminophenyl)(indolin-1-yl)methanone chemical structure, C15H14N2O, CAS 21859-87-0
(2-Aminophenyl)(indolin-1-yl)methanone
CAS 21859-87-0C15H14N2O
2,3-Dihydroindol-1-yl-(2-fluorophenyl)methanone chemical structure, C15H12FNO, CAS 321531-99-1
2,3-Dihydroindol-1-yl-(2-fluorophenyl)methanone
CAS 321531-99-1C15H12FNO
(2-Chlorophenyl)(indolin-1-yl)methanone chemical structure, C15H12ClNO, CAS 293765-21-6
(2-Chlorophenyl)(indolin-1-yl)methanone
CAS 293765-21-6C15H12ClNO
(3,5-Difluorophenyl)-(2-methyl-2,3-dihydroindol-1-yl)methanone chemical structure, C16H13F2NO, CAS 351060-72-5
(3,5-Difluorophenyl)-(2-methyl-2,3-dihydroindol-1-yl)methanone
CAS 351060-72-5C16H13F2NO
2,3-Dihydroindol-1-yl-(2-methyl-3-nitrophenyl)methanone chemical structure, C16H14N2O3, CAS 346692-20-4
2,3-Dihydroindol-1-yl-(2-methyl-3-nitrophenyl)methanone
CAS 346692-20-4C16H14N2O3
(5-Bromo-2,3-dihydroindol-1-yl)-[3-(trifluoromethyl)phenyl]methanone chemical structure, C16H11BrF3NO, CAS 346663-01-2
(5-Bromo-2,3-dihydroindol-1-yl)-[3-(trifluoromethyl)phenyl]methanone
CAS 346663-01-2C16H11BrF3NO
(2,3-Dihydro-indol-1-yl)-(2-methoxy-4-methylsulfanyl-phenyl)-methanone chemical structure, C17H17NO2S, CAS 347310-35-4
(2,3-Dihydro-indol-1-yl)-(2-methoxy-4-methylsulfanyl-phenyl)-methanone
CAS 347310-35-4C17H17NO2S
(2-Chloro-5-nitrophenyl)-(2,3-dihydroindol-1-yl)methanone chemical structure, C15H11ClN2O3, CAS 330657-71-1
(2-Chloro-5-nitrophenyl)-(2,3-dihydroindol-1-yl)methanone
CAS 330657-71-1C15H11ClN2O3
(2-Methylindolin-1-yl)(3,4,5-trimethoxyphenyl)methanone chemical structure, C19H21NO4, CAS 333352-31-1
(2-Methylindolin-1-yl)(3,4,5-trimethoxyphenyl)methanone
CAS 333352-31-1C19H21NO4
Indolin-1-yl(2-iodophenyl)methanone chemical structure, C15H12INO, CAS 346699-59-0
Indolin-1-yl(2-iodophenyl)methanone
CAS 346699-59-0C15H12INO
(3-Chlorophenyl)(indolin-1-yl)methanone chemical structure, C15H12ClNO, CAS 330468-96-7
(3-Chlorophenyl)(indolin-1-yl)methanone
CAS 330468-96-7C15H12ClNO
(2,3-Dihydro-1H-indol-1-yl)(4-fluorophenyl)methanone chemical structure, C15H12FNO, CAS 90172-60-4
(2,3-Dihydro-1H-indol-1-yl)(4-fluorophenyl)methanone
CAS 90172-60-4C15H12FNO
RefChem:381373 chemical structure, C17H17NO3, CAS 128581-33-9
RefChem:381373
CAS 128581-33-9C17H17NO3
2,3-Dihydroindol-1-yl-(3,4-dimethylphenyl)methanone chemical structure, C17H17NO, CAS 333348-39-3
2,3-Dihydroindol-1-yl-(3,4-dimethylphenyl)methanone
CAS 333348-39-3C17H17NO
1-(4-Ethoxybenzoyl)indoline chemical structure, C17H17NO2, CAS 346693-88-7
1-(4-Ethoxybenzoyl)indoline
CAS 346693-88-7C17H17NO2
(3,4-Dichlorophenyl)(indolin-1-yl)methanone chemical structure, C15H11Cl2NO, CAS 61589-15-9
(3,4-Dichlorophenyl)(indolin-1-yl)methanone
CAS 61589-15-9C15H11Cl2NO
1-(3-Bromo-4-methoxybenzoyl)indoline chemical structure, C16H14BrNO2, CAS 327069-61-4
1-(3-Bromo-4-methoxybenzoyl)indoline
CAS 327069-61-4C16H14BrNO2
1-(3-Bromo-4-methylbenzoyl)indoline chemical structure, C16H14BrNO, CAS 444059-34-1
1-(3-Bromo-4-methylbenzoyl)indoline
CAS 444059-34-1C16H14BrNO
2,3-Dihydroindol-1-yl-(3-nitrophenyl)methanone chemical structure, C15H12N2O3, CAS 312268-26-1
2,3-Dihydroindol-1-yl-(3-nitrophenyl)methanone
CAS 312268-26-1C15H12N2O3