CompoundList
Sign in
Murcko scaffold

2-(1H-Pyrazol-1-yl)pyrimidine scaffold

325 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
325
With full pages
27
Scaffold SMILES

c1cnc(-n2cccn2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-1-yl)pyrimidine page
Murcko scaffold c1cnc(-n2cccn2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 325 chemicals

Epirizole chemical structure, C11H14N4O2, CAS 18694-40-1
Epirizole
CAS 18694-40-1C11H14N4O2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N,6-dimethylpyrimidin-4-amine chemical structure, C11H15N5, CAS 73029-69-3
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N,6-dimethylpyrimidin-4-amine
CAS 73029-69-3C11H15N5
Ethyl 5-amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C12H15N5O2, CAS 91644-39-2
Ethyl 5-amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazole-4-carboxylate
CAS 91644-39-2C12H15N5O2
4-Chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidine chemical structure, C10H11ClN4, CAS 65004-43-5
4-Chloro-2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-methylpyrimidine
CAS 65004-43-5C10H11ClN4
2-[[2-(3,5-Dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]-(2-hydroxyethyl)amino]ethanol chemical structure, C14H21N5O2, CAS 92328-44-4
2-[[2-(3,5-Dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]-(2-hydroxyethyl)amino]ethanol
CAS 92328-44-4C14H21N5O2
2-[[2-(3,5-Dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]amino]ethanol chemical structure, C12H17N5O, CAS 378756-88-8
2-[[2-(3,5-Dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]amino]ethanol
CAS 378756-88-8C12H17N5O
5-Amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C10H10N6, CAS 56898-44-3
5-Amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 56898-44-3C10H10N6
N-[2-(4,6-Dimethylpyrimidin-2-yl)-5-methylpyrazol-3-yl]-2-methylpropanamide chemical structure, C14H19N5O, CAS 379266-31-6
N-[2-(4,6-Dimethylpyrimidin-2-yl)-5-methylpyrazol-3-yl]-2-methylpropanamide
CAS 379266-31-6C14H19N5O
Ethyl 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C10H11N5O2, CAS 91129-95-2
Ethyl 5-amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carboxylate
CAS 91129-95-2C10H11N5O2
1-(4,6-Dimethylpyrimidin-2-yl)-3-methyl-1H-pyrazol-5-amine chemical structure, C10H13N5, CAS 475653-98-6
1-(4,6-Dimethylpyrimidin-2-yl)-3-methyl-1H-pyrazol-5-amine
CAS 475653-98-6C10H13N5
2-Chloro-N-(1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-1H-pyrazol-5-yl)acetamide chemical structure, C12H14ClN5O, CAS 381165-95-3
2-Chloro-N-(1-(4,6-dimethylpyrimidin-2-yl)-3-methyl-1H-pyrazol-5-yl)acetamide
CAS 381165-95-3C12H14ClN5O
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-5-pyrimidinecarbonitrile chemical structure, C10H9N5, CAS 321385-84-6
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-5-pyrimidinecarbonitrile
CAS 321385-84-6C10H9N5
4-Amino-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine-5-carbonitrile chemical structure, C10H10N6, CAS 90842-94-7
4-Amino-2-(3,5-dimethyl-1H-pyrazol-1-yl)pyrimidine-5-carbonitrile
CAS 90842-94-7C10H10N6
2-(3,5-Dimethyl-pyrazol-1-yl)-4,6-dimethyl-pyrimidine chemical structure, C11H14N4, CAS 4086-61-7
2-(3,5-Dimethyl-pyrazol-1-yl)-4,6-dimethyl-pyrimidine
CAS 4086-61-7C11H14N4
N-[4-Cyano-2-(4,6-dimethylpyrimidin-2-yl)pyrazol-3-yl]acetamide chemical structure, C12H12N6O, CAS 897552-26-0
N-[4-Cyano-2-(4,6-dimethylpyrimidin-2-yl)pyrazol-3-yl]acetamide
CAS 897552-26-0C12H12N6O
N-[4-Cyano-2-(4,6-dimethylpyrimidin-2-yl)pyrazol-3-yl]propanamide chemical structure, C13H14N6O, CAS 891445-95-7
N-[4-Cyano-2-(4,6-dimethylpyrimidin-2-yl)pyrazol-3-yl]propanamide
CAS 891445-95-7C13H14N6O
N,N-Bis(2-methoxyethyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C14H20N6O4, CAS 1001607-99-3
N,N-Bis(2-methoxyethyl)-6-methyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001607-99-3C14H20N6O4
N,N,6-trimethyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine chemical structure, C10H12N6O2, CAS 1001608-05-4
N,N,6-trimethyl-2-(4-nitro-1H-pyrazol-1-yl)pyrimidin-4-amine
CAS 1001608-05-4C10H12N6O2
4-Ethoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine chemical structure, C10H12N4O, CAS 114834-01-4
4-Ethoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine
CAS 114834-01-4C10H12N4O
4-Methyl-2-(1H-pyrazol-1-yl)pyrimidine chemical structure, C8H8N4, CAS 183552-62-7
4-Methyl-2-(1H-pyrazol-1-yl)pyrimidine
CAS 183552-62-7C8H8N4
4-Methoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine chemical structure, C9H10N4O, CAS 114833-96-4
4-Methoxy-6-methyl-2-(1H-pyrazol-1-yl)pyrimidine
CAS 114833-96-4C9H10N4O
2-(1H-Pyrazol-1-yl)pyrimidine chemical structure, C7H6N4, CAS 82882-56-2
2-(1H-Pyrazol-1-yl)pyrimidine
CAS 82882-56-2C7H6N4
1-[1-(Pyrimidin-2-yl)-1H-pyrazol-4-yl]ethan-1-one chemical structure, C9H8N4O, CAS 852807-24-0
1-[1-(Pyrimidin-2-yl)-1H-pyrazol-4-yl]ethan-1-one
CAS 852807-24-0C9H8N4O
5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile chemical structure, C8H6N6, CAS 89978-00-7
5-Amino-1-(pyrimidin-2-yl)-1H-pyrazole-4-carbonitrile
CAS 89978-00-7C8H6N6