Murcko scaffold
Ring system with 2 rings and 15 atoms
223 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 223
- With full pages
- 6
Scaffold SMILES
O=C(NC1CCC1)OCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 223 chemicals
Trans-2-(((benzyloxy)carbonyl)amino)cyclobutane-1-carboxylic acid
CAS 904244-58-2C13H15NO4
1-(Benzyloxycarbonylamino)-cyclobutyl-1-carboxylic acid
CAS 190004-53-6C13H15NO4
Methyl 5-((1S,2R)-2-(benzyloxycarbonylamino)cyclobutanecarboxamido)pentanoate
CAS 868364-59-4C19H26N2O5
![Benzyl N-[3-(hydroxymethyl)cyclobutyl]carbamate chemical structure, C13H17NO3, CAS 130368-99-9](/s/BTMUCLCAHZZORQ-UHFFFAOYSA-N.svg)
Benzyl N-[3-(hydroxymethyl)cyclobutyl]carbamate
CAS 130368-99-9C13H17NO3
Benzyl (3-hydroxycyclobutyl)carbamate
CAS 130396-60-0C12H15NO3
![(1S,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclobutane-1-carboxylic acid chemical structure, C13H15NO4, CAS 685508-28-5](/s/ZNRUEEQIUVKKBL-WDEREUQCSA-N.svg)
(1S,2R)-2-{[(Benzyloxy)carbonyl]amino}cyclobutane-1-carboxylic acid
CAS 685508-28-5C13H15NO4
Trans-2-Benzyloxycarbonylaminocyclobutanecarboxylic acid
CAS 1212272-03-1C13H15NO4
Benzyl 3-aminocyclobutylcarbamate
CAS 1188264-84-7C12H16N2O2
Rac-(1s,3s)-3-(((benzyloxy)carbonyl)amino)cyclobutane-1-carboxylic acid
CAS 1212380-76-1C13H15NO4
Benzyl (3-(methylamino)cyclobutyl)carbamate
CAS 1201825-73-1C13H18N2O2
Benzyl N-(3,3-dimethoxycyclobutyl)carbamate
CAS 1268519-53-4C14H19NO4
Benzyl (3,3-dimethylcyclobutyl)carbamate
CAS 1529781-93-8C14H19NO2
![Carbamic acid, [1-(bromoacetyl)cyclobutyl]-, phenylmethyl ester chemical structure, C14H16BrNO3, CAS 735287-31-7](/s/AODXJSSKRVVFJN-UHFFFAOYSA-N.svg)
Carbamic acid, [1-(bromoacetyl)cyclobutyl]-, phenylmethyl ester
CAS 735287-31-7C14H16BrNO3
Benzyl 3,3-difluorocyclobutylcarbamate
CAS 939399-53-8C12H13F2NO2
amino}cyclobutane-1-carboxylic acid chemical structure, C14H17NO4, CAS 1408729-60-1](/s/HHLMEUOVRHDBLJ-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl](methyl)amino}cyclobutane-1-carboxylic acid
CAS 1408729-60-1C14H17NO4
![Benzyl 3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutylcarbamate chemical structure, C18H26N2O4, CAS 1353500-34-1](/s/WLEVVGXTYZAXJC-UHFFFAOYSA-N.svg)
Benzyl 3-[(tert-butoxycarbonyl)(methyl)amino]cyclobutylcarbamate
CAS 1353500-34-1C18H26N2O4
(3-Hydroxy-3-hydroxymethylcyclobutyl)carbamic acid benzyl ester
CAS 1272667-84-1C13H17NO4
![1-{[(Benzyloxy)carbonyl]amino}-3-hydroxycyclobutane-1-carboxylic acid chemical structure, C13H15NO5, CAS 2287272-60-8](/s/VYUQUBUBHQTDKZ-UHFFFAOYSA-N.svg)
1-{[(Benzyloxy)carbonyl]amino}-3-hydroxycyclobutane-1-carboxylic acid
CAS 2287272-60-8C13H15NO5
![3-{[(Benzyloxy)carbonyl]amino}-1-hydroxycyclobutane-1-carboxylic acid chemical structure, C13H15NO5, CAS 2287520-09-4](/s/BKNJDADBHDRMPM-UHFFFAOYSA-N.svg)
3-{[(Benzyloxy)carbonyl]amino}-1-hydroxycyclobutane-1-carboxylic acid
CAS 2287520-09-4C13H15NO5
Methyl cis-3-(benzyloxycarbonylamino)cyclobutanecarboxylate
CAS 2306254-50-0C14H17NO4
![Benzyl N-[3-(2-hydroxypropan-2-yl)cyclobutyl]carbamate chemical structure, C15H21NO3, CAS 2303532-42-3](/s/MFKLXPVCBADUHU-UHFFFAOYSA-N.svg)
Benzyl N-[3-(2-hydroxypropan-2-yl)cyclobutyl]carbamate
CAS 2303532-42-3C15H21NO3
cis-2-Benzyloxycarbonylaminocyclobutanecarboxylic acid
C13H15NO4
Benzyl N-(1-cyanocyclobutyl)carbamate
CAS 940868-20-2C13H14N2O2
Benzyl N-(3-fluorocyclobutyl)carbamate
CAS 1451392-68-9C12H14FNO2
- 2-(1-(Benzyloxycarbonyl)cyclobutyl)acetic acid1531669-06-3C14H17NO4
- Benzyl N-[1-(hydroxymethyl)cyclobutyl]carbamate144877-12-3C13H17NO3
- Benzyl (3-formylcyclobutyl)carbamate188412-27-3C13H15NO3
- Benzyl N-(3-hydroxy-1-methylcyclobutyl)carbamate1428776-45-7C13H17NO3
- rac-Benzyl N-[(1R,2S)-2-(hydroxymethyl)cyclobutyl]carbamate1443928-97-9C13H17NO3
- Benzyl tert-butyl (1S,2S)-cyclobutane-1,2-diylbiscarbamate1374222-84-0C17H24N2O4
- Benzyl tert-butyl (1R,2R)-cyclobutane-1,2-diylbiscarbamate1374222-07-7C17H24N2O4
- (1S,3R)-3-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclobutane-1-carboxylic acid1017279-82-1C15H19NO4
- Benzyl N-cyclobutyl-N-(2-hydroxyethyl)carbamate1602272-43-4C14H19NO3
- Benzyl N-cyclobutyl-N-(3-hydroxypropyl)carbamate1595622-68-6C15H21NO3
- 1-{[(Benzyloxy)carbonyl]amino}-3-methylcyclobutane-1-carboxylic acid1697926-72-9C14H17NO4
- 1-{[(Benzyloxy)carbonyl]amino}-3-methoxycyclobutane-1-carboxylic acid2287273-68-9C14H17NO5
- 1-{[(Benzyloxy)carbonyl](methyl)amino}-3-methoxycyclobutane-1-carboxylic acid1698465-40-5C15H19NO5
- Benzyl (3-hydroxy-2,2-dimethylcyclobutyl)carbamate1593474-15-7C14H19NO3
- Benzyl N-[3,3-bis(hydroxymethyl)cyclobutyl]carbamate1659188-81-4C14H19NO4
- Benzyl (1-carbamoylcyclobutyl)carbamate1936317-66-6C13H16N2O3
- Benzyl (3,3-difluorocyclobutyl)(methyl)carbamate1956306-91-4C13H15F2NO2
- 1-{[(Benzyloxy)carbonyl]amino}-3,3-dimethylcyclobutane-1-carboxylic acid1935520-14-1C15H19NO4
- 1-{[(Benzyloxy)carbonyl]amino}-3,3-difluorocyclobutane-1-carboxylicacid1936233-31-6C13H13F2NO4
- 3-{[(Benzyloxy)carbonyl]amino}-3-(trifluoromethyl)cyclobutane-1-carboxylic acid1993314-53-6C14H14F3NO4
- rac-Benzyl N-((1s,3s)-3-aminocyclobutyl)carbamate hydrochloride1989638-13-2C12H17ClN2O2
- 3-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclobutane-1-carboxylic acid1934700-03-4C15H19NO4
- 1-{[(Benzyloxy)carbonyl]amino}-3-(tert-butoxy)cyclobutane-1-carboxylic acid2059987-74-3C17H23NO5
- 1-{[(Benzyloxy)carbonyl]amino}-2,2-dimethylcyclobutane-1-carboxylic acid1871475-29-4C15H19NO4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(NC1CNC1)OCc1ccccc13 chemicals
O=C(NC1COC1=O)OCc1ccccc12 chemicals
S=C(NN=Cc1ccccn1)N1CCC12 chemicals
O=C(NC(=S)Nc1ccccc1)C1CCC12 chemicals
C=C1CC(NC(=O)OCc2ccccc2)C11 chemical
O=C(NNC(=O)C1CCC1)c1ccccc11 chemical
c1ccc(CCCOC2CNC2)cc11 chemical
O=C(NC1COC1)OCc1ccccc11 chemical
O=C(COC(=O)C1CCC1)c1ccccc11 chemical
O=C(C=C1CNC1)OCc1ccccc11 chemical