Murcko scaffold
Ethenocytosine scaffold
30 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 30
- With full pages
- 4
Scaffold SMILES
O=c1[nH]ccc2nccn12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]ccc2nccn12](/scaffold/GICKXGZWALFYHZ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 30 of 30 chemicals
![2,6-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C8H9N3O, CAS 57491-47-1](/s/QWZGCIKZDYSZLW-UHFFFAOYSA-N.svg)
2,6-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 57491-47-1C8H9N3O
![3,6-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C8H9N3O, CAS 57491-48-2](/s/CTFSZJVALNKHJW-UHFFFAOYSA-N.svg)
3,6-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 57491-48-2C8H9N3O
![7-Chloroimidazo[1,2-c]pyrimidin-5-ol chemical structure, C6H4ClN3O, CAS 56817-09-5](/s/MORDDYJPVSRHAG-UHFFFAOYSA-N.svg)
7-Chloroimidazo[1,2-c]pyrimidin-5-ol
CAS 56817-09-5C6H4ClN3O
![7-Aminoimidazo[1,2-c]pyrimidin-5(1H)-one chemical structure, C6H6N4O, CAS 252230-10-7](/s/HKBKQEOSUUMRCX-UHFFFAOYSA-N.svg)
7-Aminoimidazo[1,2-c]pyrimidin-5(1H)-one
CAS 252230-10-7C6H6N4O
![2-Chloro-6-propylimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C9H10ClN3O, CAS 61671-70-3](/s/JDPJFGVGWUFMNH-UHFFFAOYSA-N.svg)
2-Chloro-6-propylimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 61671-70-3C9H10ClN3O
![7-Methylimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C7H7N3O, CAS 55662-67-4](/s/PNQKWFDQEJLJPY-UHFFFAOYSA-N.svg)
7-Methylimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 55662-67-4C7H7N3O
![5-Oxo-5H,6H-imidazo[1,2-c]pyrimidine-7-carboxylic acid chemical structure, C7H5N3O3, CAS 1784874-23-2](/s/RNTZHOMQHSROIX-UHFFFAOYSA-N.svg)
5-Oxo-5H,6H-imidazo[1,2-c]pyrimidine-7-carboxylic acid
CAS 1784874-23-2C7H5N3O3
![Ethyl 7-chloro-5-hydroxyimidazo[1,2-c]pyrimidine-2-carboxylate chemical structure, C9H8ClN3O3, CAS 1639974-70-1](/s/CUJBYAJHJNMBJS-UHFFFAOYSA-N.svg)
Ethyl 7-chloro-5-hydroxyimidazo[1,2-c]pyrimidine-2-carboxylate
CAS 1639974-70-1C9H8ClN3O3
![7-(Trifluoromethyl)imidazo[1,2-C]pyrimidin-5-ol chemical structure, C7H4F3N3O, CAS 2055901-34-1](/s/JKJCWBJODPIOOJ-UHFFFAOYSA-N.svg)
7-(Trifluoromethyl)imidazo[1,2-C]pyrimidin-5-ol
CAS 2055901-34-1C7H4F3N3O
Ethenocytosine
CAS 55662-66-3C6H5N3O
![2,3-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C8H9N3O, CAS 35536-41-5](/s/SZLMEJSLDPKTCG-UHFFFAOYSA-N.svg)
2,3-Dimethylimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 35536-41-5C8H9N3O
![7-Chloro-2-methyl-6H-imidazo[1,2-c]pyrimidin-5-one chemical structure, C7H6ClN3O, CAS 1059191-51-3](/s/OOTCEFXMBZQTPF-UHFFFAOYSA-N.svg)
7-Chloro-2-methyl-6H-imidazo[1,2-c]pyrimidin-5-one
CAS 1059191-51-3C7H6ClN3O
![7-Chloro-2-trifluoromethyl-imidazo[1,2-C]pyrimidin-5-ol chemical structure, C7H3ClF3N3O, CAS 1059191-45-5](/s/JIGKHZROAWKXGD-UHFFFAOYSA-N.svg)
7-Chloro-2-trifluoromethyl-imidazo[1,2-C]pyrimidin-5-ol
CAS 1059191-45-5C7H3ClF3N3O
![8-Bromoimidazo[1,2-c]pyrimidin-5(6H)-one chemical structure, C6H4BrN3O, CAS 1369153-25-2](/s/OKWIXNKNCLTZEK-UHFFFAOYSA-N.svg)
8-Bromoimidazo[1,2-c]pyrimidin-5(6H)-one
CAS 1369153-25-2C6H4BrN3O
![2-Ethyl-5,6-dihydro-5-oxoimidazo[1,2-c]pyrimidine-3-carboxaldehyde chemical structure, C9H9N3O2, CAS 100289-25-6](/s/VBUIMLJWPMACFY-UHFFFAOYSA-N.svg)
2-Ethyl-5,6-dihydro-5-oxoimidazo[1,2-c]pyrimidine-3-carboxaldehyde
CAS 100289-25-6C9H9N3O2
![5-Oxo-5,6-dihydroimidazo[1,2-c]pyrimidine-2-carboxylic acid chemical structure, C7H5N3O3, CAS 1403332-76-2](/s/UXVAOQOUWHBNPO-UHFFFAOYSA-N.svg)
5-Oxo-5,6-dihydroimidazo[1,2-c]pyrimidine-2-carboxylic acid
CAS 1403332-76-2C7H5N3O3
![5-Oxo-1,5-dihydroimidazo[1,2-c]pyrimidine-2-carbaldehyde chemical structure, C7H5N3O2, CAS 1369247-45-9](/s/POEQUZHKOKCGAA-UHFFFAOYSA-N.svg)
5-Oxo-1,5-dihydroimidazo[1,2-c]pyrimidine-2-carbaldehyde
CAS 1369247-45-9C7H5N3O2
![3-Bromoimidazo[1,2-c]pyrimidin-5-ol chemical structure, C6H4BrN3O, CAS 1780432-03-2](/s/FFUSQFPLTIMHPE-UHFFFAOYSA-N.svg)
3-Bromoimidazo[1,2-c]pyrimidin-5-ol
CAS 1780432-03-2C6H4BrN3O
![Ethyl 5-oxo-5,6-dihydroimidazo[1,2-c]pyrimidine-2-carboxylate chemical structure, C9H9N3O3, CAS 1403332-74-0](/s/HOMUSTSFVNRTAX-UHFFFAOYSA-N.svg)
Ethyl 5-oxo-5,6-dihydroimidazo[1,2-c]pyrimidine-2-carboxylate
CAS 1403332-74-0C9H9N3O3
![8-Iodo-6H-imidazo[1,2-c]pyrimidin-5-one chemical structure, C6H4IN3O, CAS 1639927-31-3](/s/QYBVGWFSIYHZEG-UHFFFAOYSA-N.svg)
8-Iodo-6H-imidazo[1,2-c]pyrimidin-5-one
CAS 1639927-31-3C6H4IN3O
![Ethyl 5,6-dihydro-7-methoxy-5-oxoimidazo[1,2-c]pyrimidine-2-carboxylate chemical structure, C10H11N3O4, CAS 2101786-36-9](/s/VHQIBRPDZVSCAG-UHFFFAOYSA-N.svg)
Ethyl 5,6-dihydro-7-methoxy-5-oxoimidazo[1,2-c]pyrimidine-2-carboxylate
CAS 2101786-36-9C10H11N3O4
![3-Bromoimidazo[1,2-c]pyrimidin-5-ol hydrochloride chemical structure, C6H5BrClN3O, CAS 2172603-84-6](/s/LYIFSMZFQJIBHP-UHFFFAOYSA-N.svg)
3-Bromoimidazo[1,2-c]pyrimidin-5-ol hydrochloride
CAS 2172603-84-6C6H5BrClN3O
![Ethyl 8-bromo-5-oxo-6H-imidazo[1,2-c]pyrimidine-2-carboxylate chemical structure, C9H8BrN3O3, CAS 2369771-65-1](/s/JLQPWNMJSJOARH-UHFFFAOYSA-N.svg)
Ethyl 8-bromo-5-oxo-6H-imidazo[1,2-c]pyrimidine-2-carboxylate
CAS 2369771-65-1C9H8BrN3O3
![8-Bromo-7-methylimidazo[1,2-c]pyrimidin-5-ol chemical structure, C7H6BrN3O, CAS 2414519-63-2](/s/RFHJWMAYSYEQFY-UHFFFAOYSA-N.svg)
8-Bromo-7-methylimidazo[1,2-c]pyrimidin-5-ol
CAS 2414519-63-2C7H6BrN3O
- 8-Fluoroimidazo[1,2-c]pyrimidin-5(6H)-one1353100-75-0C6H4FN3O
- 8-Bromo-5-oxo-6H-imidazo[1,2-c]pyrimidine-2-carboxylic acid2369771-67-3C7H4BrN3O3
- 8-Bromo-5,6-dihydro-5-oxoimidazo[1,2-c]pyrimidine-2-carboxamide2369771-68-4C7H5BrN4O2
- Ethyl 7-bromo-5-oxo-6H-imidazo[1,2-c]pyrimidine-2-carboxylate2750362-59-3C9H8BrN3O3
- 7-Methylimidazo[1,2-c]pyrimidin-5-ol hydrobromide3037705-67-9C7H8BrN3O
- 8-Bromo-5-hydroxyimidazo[1,2-c]pyrimidine-3-carbaldehyde3048717-15-0C7H4BrN3O2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ccc2c12,455 chemicals![Scaffold c1ccc2[nH]cnc2c1](/scaffold/HYZJCKYKOHLVJF-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals