Murcko scaffold
Ring system with 2 rings and 20 atoms
63 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 20
- Chemicals
- 63
- With full pages
- 0
Scaffold SMILES
O=C(CNC(=O)C1CCCN1)NCC(=O)N1CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 63 chemicals
H-Ala-Leu-Leu-Pro-Ala-Val-Pro-Ser-Leu-OH
CAS 263268-96-8C42H73N9O11
L-Proline, L-alanyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-
CAS 503844-11-9C28H48N6O7
L-Proline, L-valyl-L-leucyl-L-prolyl-L-alanyl-L-alanyl-
CAS 506415-80-1C27H46N6O7
L-Proline, glycyl-L-valyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-
CAS 201351-02-2C32H55N7O8
L-Proline, L-valyl-L-alanyl-L-prolyl-L-alanyl-L-leucyl-
CAS 503844-12-0C27H46N6O7
L-Alanine, L-valyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-prolyl-
CAS 503844-18-6C33H57N7O8
L-Glutamine, L-alanyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-prolyl-
CAS 503844-13-1C33H56N8O9
L-alpha-Glutamyl-l-methionyl-l-threonyl-(4r)-4-hydroxy-l-prolyl-l-valyl-l-asparaginyl-(4r)-4-hydroxy-l-prolyl-glycine
CAS 393827-71-9C35H57N9O15S
L-Glutamine, L-valyl-L-leucyl-L-prolyl-L-alanyl-L-alanyl-L-prolyl-
CAS 503844-14-2C32H54N8O9
H-Ala-Ala-Pro-Gly-Ala-Pro-Ala-Ala-Val-OH
CAS 651327-48-9C32H53N9O10
L-Proline, glycyl-L-prolyl-L-isoleucylglycyl-
CAS 56672-77-6C20H33N5O6
L-Cysteine, L-arginyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-prolylglycyl-
CAS 656228-87-4C33H58N14O10S
H-Cys-Gly-Arg-Ala-Pro-Arg-Ser-Pro-OH
CAS 656228-83-0C33H58N14O10S
L-Leucine, L-isoleucyl-L-prolylglycyl-L-leucyl-L-prolyl-L-leucyl-L-seryl-
CAS 158442-98-9C39H68N8O10
L-Proline, L-arginyl-L-arginyl-L-isoleucyl-L-prolyl-L-leucyl-L-seryl-
CAS 854274-99-0C37H67N13O9
L-Arginine, L-prolyl-L-arginyl-L-threonyl-L-prolylglycylglycyl-
CAS 671216-89-0C30H53N13O9
L-Valyl-L-prolyl-L-isoleucyl-L-threonyl-L-prolyl-L-threonyl-L-leucine
CAS 922713-44-8C35H61N7O10
L-Valyl-L-prolyl-L-isoleucyl-L-threonyl-L-prolyl-L-threonine
CAS 922713-33-5C29H50N6O9
L-Glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-prolyl-L-leucyl-L-valylglycine
CAS 920742-94-5C37H63N9O10
Hexapeptide-9
CAS 885024-94-2C24H38N8O9
L-Prolyl-L-lysyl-L-alanyl-L-prolyl-L-seryl-L-alanyl-L-glutamine
CAS 246018-81-5C30H51N9O10
Galanin Message Associated Peptide (44-59) amide
CAS 125455-59-6C61H100N18O25
MBP MAPK Substrate
CAS 138028-00-9C39H70N18O11
L-Seryl-L-isoleucyl-L-isoleucyl-L-prolylglycyl-L-leucyl-L-prolyl-L-leucine
CAS 184576-66-7C39H68N8O10
- L-Prolyl-L-leucylglycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithine179899-85-5C24H42N8O6
- L-Leucyl-L-prolyl-L-alanyl-L-leucyl-L-proline178885-52-4C25H43N5O6
- H-Pro-Thr-Ile-Pro-OH126357-96-8C20H34N4O6
- H-Gly-Ala-Pro-Gly-Ala-Pro-OH114414-94-7C20H32N6O7
- L-Cysteinyl-L-prolyl-L-seryl-L-cysteinyl-L-proline220013-87-6C19H31N5O7S2
- L-Prolyl-L-threonyl-L-alanyl-L-proline460052-20-4C17H28N4O6
- Glycyl-L-prolylglycylglycyl-L-prolylglycine5891-39-4C18H28N6O7
- Glycyl-L-prolyl-L-leucyl-L-alanyl-L-proline67119-98-6C21H35N5O6
- L-Prolyl-L-seryl-L-seryl-L-proline680987-84-2C16H26N4O7
- N~5~-(Diaminomethylidene)-L-ornithyl-L-alanyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-seryl-L-proline656228-82-9C28H50N12O8
- Glycyl-L-valyl-L-alanyl-L-prolyl-L-alanyl-L-leucyl-L-prolylglycyl-L-glutamine646061-73-6C36H60N10O11
- L-Prolyl-L-asparaginyl-L-alanyl-L-prolyl-L-isoleucyl-L-leucyl-L-serine630401-57-9C32H54N8O10
- L-Prolyl-L-alanylglycyl-L-prolyl-L-alanylglycine62286-41-3C20H32N6O7
- L-Prolyl-L-threonyl-L-leucyl-L-proline773883-26-4C20H34N4O6
- Glycyl-L-prolyl-L-isoleucyl-L-leucyl-L-prolylglycyl-L-threonyl-L-lysine776304-60-0C36H63N9O10
- L-Glutaminyl-L-prolyl-L-seryl-L-glutaminyl-L-prolylglycylglycyl-L-valine742068-40-2C32H52N10O12
- L-Prolyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-threonine872438-52-3C28H50N12O8
- L-Prolyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithine872438-47-6C24H43N11O6
- Glycyl-L-prolyl-L-seryl-L-seryl-L-prolyl-L-serylglycyl-L-lysyl-L-leucine834902-24-8C35H60N10O13
- L-Leucyl-L-prolyl-L-seryl-L-seryl-L-proline832731-19-8C22H37N5O8
- L-Prolyl-L-methionyl-L-asparaginyl-L-proline915224-06-5C19H31N5O6S
- 1-{[(Prop-2-en-1-yl)oxy]carbonyl}-L-prolyl-L-alanylglycyl-L-proline573690-71-8C19H28N4O7
- L-Leucyl-L-valyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine532391-71-2C40H72N14O9
- L-Prolyl-L-lysyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithine583824-02-6C34H64N16O7
Related scaffolds
Same ring framework with different atoms or bond orders
O=C1OCC=C1CCCCCCCC1CCCO12 chemicals
O=C(NCCCNC(=O)c1cccs1)c1cccs12 chemicals
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O=C(CNC(=O)c1cccs1)NN=Cc1ccco12 chemicals
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O=C(NCCCNC(=O)c1ccco1)c1ccco11 chemical
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O=C(CCNC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O1 chemical
O=C(CCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O1 chemical
O=C(NCC(=O)ON1C(=O)CCC1=O)NCc1cscn11 chemical![Scaffold O=C(CNC(=O)c1ccco1)OCC(=O)c1cc[nH]c1](/scaffold/QIYMQJCSPLFJAG-UHFFFAOYSA-N/structure.svg)
O=C(CNC(=O)c1ccco1)OCC(=O)c1cc[nH]c11 chemical