Murcko scaffold
3-(2-Phenylethyl)pyrrolidine scaffold
56 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 56
- With full pages
- 1
Scaffold SMILES
c1ccc(CCC2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 56 chemicals
3-(2-Phenylethyl)pyrrolidine
CAS 613676-70-3C12H17N
![3-[2-(4-Fluorophenyl)ethyl]pyrrolidine chemical structure, C12H16FN, CAS 1379268-15-1](/s/FHWUYVPLVQVFIE-UHFFFAOYSA-N.svg)
3-[2-(4-Fluorophenyl)ethyl]pyrrolidine
CAS 1379268-15-1C12H16FN
3-(2-Fluorophenethyl)pyrrolidine
CAS 614731-18-9C12H16FN
3-(2-Phenylpropyl)pyrrolidine
CAS 1220030-14-7C13H19N
tert-Butyl ((3R,4S)-4-phenethylpyrrolidin-3-yl)carbamate
CAS 1260602-53-6C17H26N2O2
3-Methyl-3-(2-phenylethyl)pyrrolidine
CAS 1248713-00-9C13H19N
3-(2-Phenylethyl)pyrrolidin-3-ol
CAS 917505-34-1C12H17NO
![(RS)-3-[2-(4-Amino-phenyl)-ethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester chemical structure, C17H26N2O2, CAS 1312565-72-2](/s/HUGRIQUJHSJKSX-UHFFFAOYSA-N.svg)
(RS)-3-[2-(4-Amino-phenyl)-ethyl]-pyrrolidine-1-carboxylic acid tert-butyl ester
CAS 1312565-72-2C17H26N2O2
![3-[2-(4-Methoxyphenyl)ethyl]pyrrolidine chemical structure, C13H19NO, CAS 913088-42-3](/s/LSUIBOOLYRRJST-UHFFFAOYSA-N.svg)
3-[2-(4-Methoxyphenyl)ethyl]pyrrolidine
CAS 913088-42-3C13H19NO
3-(3-Methylphenethyl)pyrrolidine
CAS 1509562-62-2C13H19N
3-(3-Fluorophenethyl)pyrrolidine
CAS 1516374-62-1C12H16FN
![3-[2-(3-Bromophenyl)ethyl]pyrrolidine chemical structure, C12H16BrN, CAS 1779887-04-5](/s/ZAMSHOBOLDGWIC-UHFFFAOYSA-N.svg)
3-[2-(3-Bromophenyl)ethyl]pyrrolidine
CAS 1779887-04-5C12H16BrN
![3-[2-(4-Bromophenyl)ethyl]pyrrolidine chemical structure, C12H16BrN, CAS 1784313-55-8](/s/VXSIPJPWCJBJPO-UHFFFAOYSA-N.svg)
3-[2-(4-Bromophenyl)ethyl]pyrrolidine
CAS 1784313-55-8C12H16BrN
![3-[2-(2,4,6-Trimethylphenyl)ethyl]pyrrolidine chemical structure, C15H23N, CAS 1515212-25-5](/s/ZGQAXLPTVCCTML-UHFFFAOYSA-N.svg)
3-[2-(2,4,6-Trimethylphenyl)ethyl]pyrrolidine
CAS 1515212-25-5C15H23N
![3-[2-(4-Fluorophenyl)propyl]pyrrolidine chemical structure, C13H18FN, CAS 1550726-61-8](/s/DRIJCRTZPPWGFP-UHFFFAOYSA-N.svg)
3-[2-(4-Fluorophenyl)propyl]pyrrolidine
CAS 1550726-61-8C13H18FN
![3-[2-(2,4,6-Trimethylphenyl)ethyl]pyrrolidin-3-ol chemical structure, C15H23NO, CAS 1784240-98-7](/s/WHNMTFYMEVBRLV-UHFFFAOYSA-N.svg)
3-[2-(2,4,6-Trimethylphenyl)ethyl]pyrrolidin-3-ol
CAS 1784240-98-7C15H23NO
3-(2-Phenylethyl)pyrrolidine hydrochloride
CAS 936225-50-2C12H18ClN
![3-{2-[4-(Trifluoromethyl)phenyl]propyl}pyrrolidine chemical structure, C14H18F3N, CAS 1784957-87-4](/s/ASWXURHVTIVJDU-UHFFFAOYSA-N.svg)
3-{2-[4-(Trifluoromethyl)phenyl]propyl}pyrrolidine
CAS 1784957-87-4C14H18F3N
3-(2,2-Difluoro-2-phenylethyl)pyrrolidine
CAS 1593764-32-9C12H15F2N
(3R,4S)-1-Methyl-4-phenethylpyrrolidin-3-amine
CAS 1951371-59-7C13H20N2
![3-[2-(3,5-Difluorophenyl)ethyl]pyrrolidine hydrochloride chemical structure, C12H16ClF2N, CAS 2097968-25-5](/s/CYVTZSRZKVBTPB-UHFFFAOYSA-N.svg)
3-[2-(3,5-Difluorophenyl)ethyl]pyrrolidine hydrochloride
CAS 2097968-25-5C12H16ClF2N
![3-[2-(2,5-Difluorophenyl)ethyl]pyrrolidine hydrochloride chemical structure, C12H16ClF2N, CAS 2098123-16-9](/s/CUDUWRTUTMRBMJ-UHFFFAOYSA-N.svg)
3-[2-(2,5-Difluorophenyl)ethyl]pyrrolidine hydrochloride
CAS 2098123-16-9C12H16ClF2N
![3-[2-(2-Fluorophenyl)ethyl]pyrrolidine hydrochloride chemical structure, C12H17ClFN, CAS 2097989-74-5](/s/YNYJSWJROVBYEK-UHFFFAOYSA-N.svg)
3-[2-(2-Fluorophenyl)ethyl]pyrrolidine hydrochloride
CAS 2097989-74-5C12H17ClFN
![3-[2-(3-Fluorophenyl)ethyl]pyrrolidine hydrochloride chemical structure, C12H17ClFN, CAS 1824267-63-1](/s/DRDDBLITPNLBHH-UHFFFAOYSA-N.svg)
3-[2-(3-Fluorophenyl)ethyl]pyrrolidine hydrochloride
CAS 1824267-63-1C12H17ClFN
- 3-[2-(4-Fluorophenyl)ethyl]pyrrolidine hydrochloride2098020-59-6C12H17ClFN
- Methyl 4-[2-(pyrrolidin-3-yl)ethyl]benzoate hydrochloride2098002-92-5C14H20ClNO2
- 4-[2-(Pyrrolidin-3-yl)ethyl]benzoic acid hydrochloride2098053-26-8C13H18ClNO2
- Orb25644942565657-20-5C13H18ClNO2
- (S)-3-(3-Bromophenyl)-2-[(R)-1-Boc-3-pyrrolidinyl]propanoic Acid2565657-49-8C18H24BrNO4
- tert-Butyl (R)-3-((S)-1-(tert-butoxy)-3-(3-formylphenyl)-1-oxopropan-2-yl)pyrrolidine-1-carboxylate2565657-72-7C23H33NO5
- tert-Butyl (R)-3-((S)-3-(3-bromophenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-1-carboxylate2565657-65-8C22H32BrNO4
- tert-Butyl (3R)-3-[(2S)-3-(3-hydroxyphenyl)-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]pyrrolidine-1-carboxylate2565657-83-0C22H33NO5
- tert-Butyl (R)-3-((S)-3-(3-(aminomethyl)phenyl)-1-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-1-carboxylate2565657-75-0C23H36N2O4
- 3-Phenyl-2-(pyrrolidin-3-yl)propanoic acid2565658-58-2C13H17NO2
- tert-Butyl (3R)-3-[(1S)-1-[(3-aminophenyl)methyl]-2-t-butoxy-2-oxoethyl]pyrrolidine-1-carboxylate2565657-79-4C22H34N2O4
- tert-Butyl (3R)-3-[(2S)-3-[3-(hydroxymethyl)phenyl]-1-[(2-methylpropan-2-yl)oxy]-1-oxopropan-2-yl]pyrrolidine-1-carboxylate2565657-81-8C23H35NO5
- 3-(2,2-Difluoro-2-phenylethyl)pyrrolidin-3-ol2026575-99-3C12H15F2NO
- 3-(2-Methyl-2-phenylpropyl)pyrrolidine2229338-13-8C14H21N
- tert-Butyl N-[1-phenyl-2-(pyrrolidin-3-yl)ethyl]carbamate2228157-67-1C17H26N2O2
- 3-(2-Methyl-2-phenylpropyl)pyrrolidin-3-ol2160527-23-9C14H21NO
- 2-Chloro-1-[3-(2-phenylethyl)pyrrolidin-1-yl]ethan-1-one2751611-70-6C14H18ClNO
- 3-[2-(4-Fluorophenyl)propyl]pyrrolidin-3-ol2228989-42-0C13H18FNO
- 3-[2-(2,4,5-Trifluorophenyl)ethyl]pyrrolidine2228525-09-3C12H14F3N
- tert-Butyl N-[2-(3-hydroxypyrrolidin-3-yl)-1-phenylethyl]carbamate2228506-78-1C17H26N2O3
- 3-{2-[4-(Trifluoromethyl)phenyl]propyl}pyrrolidin-3-ol2229352-97-8C14H18F3NO
- 3-(2-Phenylpropyl)pyrrolidin-3-ol1858432-22-0C13H19NO
- 3-(3-Methyl-2-phenylbutyl)pyrrolidine2229339-10-8C15H23N
- 3-(3-Methyl-2-phenylbutyl)pyrrolidin-3-ol2229265-79-4C15H23NO
Related scaffolds
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