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Murcko scaffold

Ring system with 3 rings and 20 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
10
With full pages
3
Scaffold SMILES

c1ccc(CC(c2ccccc2)c2ccccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CC(c2ccccc2)c2ccccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(3-Chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol chemical structure, C20H18ClNO, CAS 13997-39-2
1-(3-Chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol
CAS 13997-39-2C20H18ClNO
1,2-Diphenyl-1-(pyridin-2-yl)ethan-1-ol--hydrogen chloride (1/1) chemical structure, C19H18ClNO, CAS 21607-81-8
1,2-Diphenyl-1-(pyridin-2-yl)ethan-1-ol--hydrogen chloride (1/1)
CAS 21607-81-8C19H18ClNO
alpha-Ethyl-alpha,beta-diphenyl-2-pyridineethanol chemical structure, C21H21NO, CAS 5860-94-6
alpha-Ethyl-alpha,beta-diphenyl-2-pyridineethanol
CAS 5860-94-6C21H21NO
2-(4-Chlorophenyl)-1-phenyl-1-pyridin-2-ylpropan-2-ol chemical structure, C20H18ClNO, CAS 6275-95-2
2-(4-Chlorophenyl)-1-phenyl-1-pyridin-2-ylpropan-2-ol
CAS 6275-95-2C20H18ClNO
1,2-Diphenyl-1-(pyridin-2-yl)propan-2-ol chemical structure, C20H19NO, CAS 17433-73-7
1,2-Diphenyl-1-(pyridin-2-yl)propan-2-ol
CAS 17433-73-7C20H19NO
1,2-Diphenyl-1-(pyridin-2-yl)pentan-2-ol chemical structure, C22H23NO, CAS 16164-59-3
1,2-Diphenyl-1-(pyridin-2-yl)pentan-2-ol
CAS 16164-59-3C22H23NO
2-(4-Bromophenyl)-1-phenyl-1-pyridin-2-ylpropan-2-ol chemical structure, C20H18BrNO, CAS 16164-06-0
2-(4-Bromophenyl)-1-phenyl-1-pyridin-2-ylpropan-2-ol
CAS 16164-06-0C20H18BrNO
1-(3-Chlorophenyl)-2-(4-hydroxyphenyl)-1-methyl-2-(2-pyridine)ethanol chemical structure, C20H18ClNO2, CAS 58498-15-0
1-(3-Chlorophenyl)-2-(4-hydroxyphenyl)-1-methyl-2-(2-pyridine)ethanol
CAS 58498-15-0C20H18ClNO2
(AlphaS,betaS)-alpha-ethyl-alpha-(4-methoxyphenyl)-beta-phenyl-2-pyridineethanol chemical structure, C22H23NO2, CAS 16164-60-6
(AlphaS,betaS)-alpha-ethyl-alpha-(4-methoxyphenyl)-beta-phenyl-2-pyridineethanol
CAS 16164-60-6C22H23NO2
(AlphaR,betaS)-alpha-(3-chlorophenyl)-alpha-methyl-beta-phenyl-2-pyridineethanol, (±)- chemical structure, C20H18ClNO, CAS 59980-71-1
(AlphaR,betaS)-alpha-(3-chlorophenyl)-alpha-methyl-beta-phenyl-2-pyridineethanol, (±)-
CAS 59980-71-1C20H18ClNO