CompoundList
Sign in
Murcko scaffold

1'-Benzoylspiro[chroman-2,4'-piperidin]-4-one scaffold

45 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
45
With full pages
16
Scaffold SMILES

O=C1CC2(CCN(C(=O)c3ccccc3)CC2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1'-Benzoylspiro[chroman-2,4'-piperidin]-4-one page
Murcko scaffold O=C1CC2(CCN(C(=O)c3ccccc3)CC2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

1'-Benzoylspiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H19NO3, CAS 136080-49-4
1'-Benzoylspiro[chroman-2,4'-piperidin]-4-one
CAS 136080-49-4C20H19NO3
1'-(2-Methylbenzoyl)spiro[3H-chromene-2,4'-piperidine]-4-one chemical structure, C21H21NO3, CAS 877810-67-8
1'-(2-Methylbenzoyl)spiro[3H-chromene-2,4'-piperidine]-4-one
CAS 877810-67-8C21H21NO3
1'-(4-(tert-Butyl)benzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C24H27NO3, CAS 877810-71-4
1'-(4-(tert-Butyl)benzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-71-4C24H27NO3
1'-(2-Methoxybenzoyl)spiro[chromane-2,4'-piperidine]-4-one chemical structure, C21H21NO4, CAS 877810-72-5
1'-(2-Methoxybenzoyl)spiro[chromane-2,4'-piperidine]-4-one
CAS 877810-72-5C21H21NO4
1'-(3-Methoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C21H21NO4, CAS 877810-73-6
1'-(3-Methoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-73-6C21H21NO4
1'-(2-Ethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C22H23NO4, CAS 877810-75-8
1'-(2-Ethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-75-8C22H23NO4
1'-(4-Ethoxybenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one chemical structure, C22H23NO4, CAS 877810-76-9
1'-(4-Ethoxybenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one
CAS 877810-76-9C22H23NO4
1'-(4-Isopropoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C23H25NO4, CAS 877810-77-0
1'-(4-Isopropoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-77-0C23H25NO4
1'-(4-Butoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C24H27NO4, CAS 877810-78-1
1'-(4-Butoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-78-1C24H27NO4
1'-(2,3-Dimethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C22H23NO5, CAS 887466-84-4
1'-(2,3-Dimethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 887466-84-4C22H23NO5
1'-(3,4-Diethoxybenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one chemical structure, C24H27NO5, CAS 877810-81-6
1'-(3,4-Diethoxybenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one
CAS 877810-81-6C24H27NO5
1'-(3,4,5-Trimethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C23H25NO6, CAS 877810-82-7
1'-(3,4,5-Trimethoxybenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-82-7C23H25NO6
1'-(2-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18FNO3, CAS 877810-84-9
1'-(2-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-84-9C20H18FNO3
1'-(3-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18FNO3, CAS 877810-85-0
1'-(3-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-85-0C20H18FNO3
1'-(4-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18FNO3, CAS 877810-86-1
1'-(4-Fluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-86-1C20H18FNO3
1'-(2-Chlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18ClNO3, CAS 877810-87-2
1'-(2-Chlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-87-2C20H18ClNO3
1'-(3-Chlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18ClNO3, CAS 877810-88-3
1'-(3-Chlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-88-3C20H18ClNO3
1'-(2-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18BrNO3, CAS 877810-90-7
1'-(2-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-90-7C20H18BrNO3
1'-(3-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18BrNO3, CAS 877810-91-8
1'-(3-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-91-8C20H18BrNO3
1'-(4-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H18BrNO3, CAS 877810-92-9
1'-(4-Bromobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-92-9C20H18BrNO3
1'-(3,4-Difluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H17F2NO3, CAS 877810-94-1
1'-(3,4-Difluorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-94-1C20H17F2NO3
1'-(2,4-Dichlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H17Cl2NO3, CAS 877810-95-2
1'-(2,4-Dichlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-95-2C20H17Cl2NO3
1'-(2,5-Dichlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H17Cl2NO3, CAS 877810-96-3
1'-(2,5-Dichlorobenzoyl)spiro[chroman-2,4'-piperidin]-4-one
CAS 877810-96-3C20H17Cl2NO3
1'-(2-Chloro-6-fluorobenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one chemical structure, C20H17ClFNO3, CAS 877810-97-4
1'-(2-Chloro-6-fluorobenzoyl)-3,4-dihydrospiro[1-benzopyran-2,4'-piperidine]-4-one
CAS 877810-97-4C20H17ClFNO3