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Murcko scaffold

1'-Benzylspiro[chroman-2,4'-piperidin]-4-one scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
9
With full pages
1
Scaffold SMILES

O=C1CC2(CCN(Cc3ccccc3)CC2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1'-Benzylspiro[chroman-2,4'-piperidin]-4-one page
Murcko scaffold O=C1CC2(CCN(Cc3ccccc3)CC2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1'-Benzylspiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H21NO2, CAS 77264-89-2
1'-Benzylspiro[chroman-2,4'-piperidin]-4-one
CAS 77264-89-2C20H21NO2
1'-Benzyl-7-methoxy-spiro[chromane-2,4'-piperidine]-4-one chemical structure, C21H23NO3, CAS 868361-89-1
1'-Benzyl-7-methoxy-spiro[chromane-2,4'-piperidine]-4-one
CAS 868361-89-1C21H23NO3
1'-Benzyl-6-methoxyspiro[chroman-2,4'-piperidin]-4-one chemical structure, C21H23NO3, CAS 81109-71-9
1'-Benzyl-6-methoxyspiro[chroman-2,4'-piperidin]-4-one
CAS 81109-71-9C21H23NO3
1'-Benzyl-6-chlorospiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H20ClNO2, CAS 81122-68-1
1'-Benzyl-6-chlorospiro[chroman-2,4'-piperidin]-4-one
CAS 81122-68-1C20H20ClNO2
1'-Benzyl-6-bromospiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H20BrNO2, CAS 81109-72-0
1'-Benzyl-6-bromospiro[chroman-2,4'-piperidin]-4-one
CAS 81109-72-0C20H20BrNO2
1'-Benzyl-6-methylspiro[chromane-2,4'-piperidin]-4-one chemical structure, C21H23NO2, CAS 909072-47-5
1'-Benzyl-6-methylspiro[chromane-2,4'-piperidin]-4-one
CAS 909072-47-5C21H23NO2
1'-Benzyl-8-chlorospiro[chroman-2,4'-piperidin]-4-one chemical structure, C20H20ClNO2, CAS 1262757-25-4
1'-Benzyl-8-chlorospiro[chroman-2,4'-piperidin]-4-one
CAS 1262757-25-4C20H20ClNO2
1'-Benzyl-6-chlorospiro[chroman-2,4'-piperidin]-4-one hydrochloride chemical structure, C20H21Cl2NO2, CAS 81109-67-3
1'-Benzyl-6-chlorospiro[chroman-2,4'-piperidin]-4-one hydrochloride
CAS 81109-67-3C20H21Cl2NO2
1'-Benzyl-6-bromospiro[chromene-2,4'-piperidin]-4(3H)-one hydrochloride chemical structure, C20H21BrClNO2, CAS 81109-68-4
1'-Benzyl-6-bromospiro[chromene-2,4'-piperidin]-4(3H)-one hydrochloride
CAS 81109-68-4C20H21BrClNO2