Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 22 atoms

22 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 22
Chemicals: 22
With full pages: 3

Scaffold SMILES

O=c1oc(-c2ccccc2)nc2scc(-c3ccccc3)c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1oc(-c2ccccc2)nc2scc(-c3ccccc3)c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

5-(4-Methoxyphenyl)-2-(2-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C20H15NO3S, CAS 372978-41-1

5-(4-Methoxyphenyl)-2-(2-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 372978-41-1C₂₀H₁₅NO₃S

5-Phenyl-2-(3,4,5-trimethoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C21H17NO5S, CAS 380644-65-5

5-Phenyl-2-(3,4,5-trimethoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 380644-65-5C₂₁H₁₇NO₅S

5-(4-Ethoxyphenyl)-2-(4-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C20H14FNO3S, CAS 342382-39-2

5-(4-Ethoxyphenyl)-2-(4-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342382-39-2C₂₀H₁₄FNO₃S

5-(3,4-Dimethoxyphenyl)-2-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C21H17NO5S, CAS 342383-02-2

5-(3,4-Dimethoxyphenyl)-2-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342383-02-2C₂₁H₁₇NO₅S

2-(3,4-Dimethoxyphenyl)-5-phenylthiopheno[2,3-d]1,3-oxazin-4-one chemical structure, C20H15NO4S, CAS 307512-96-5

2-(3,4-Dimethoxyphenyl)-5-phenylthiopheno[2,3-d]1,3-oxazin-4-one

CAS 307512-96-5C₂₀H₁₅NO₄S

2-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C20H15NO4S, CAS 312940-88-8

2-(2-Methoxyphenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 312940-88-8C₂₀H₁₅NO₄S

2-(2-Fluorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12FNO3S, CAS 342379-31-1

2-(2-Fluorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342379-31-1C₁₉H₁₂FNO₃S

5-(4-Ethoxyphenyl)-2-(2-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C21H17NO4S, CAS 342382-38-1

5-(4-Ethoxyphenyl)-2-(2-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342382-38-1C₂₁H₁₇NO₄S

2-(4-Fluorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12FNO3S, CAS 372501-89-8

2-(4-Fluorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 372501-89-8C₁₉H₁₂FNO₃S

5-(4-Bromophenyl)-2-(2-fluorophenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C18H9BrFNO2S, CAS 342378-78-3

5-(4-Bromophenyl)-2-(2-fluorophenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 342378-78-3C₁₈H₉BrFNO₂S

5-(4-Ethoxyphenyl)-2-(2-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C21H17NO3S, CAS 443320-67-0

5-(4-Ethoxyphenyl)-2-(2-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 443320-67-0C₂₁H₁₇NO₃S

5-(4-Bromophenyl)-2-(4-tert-butylphenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C22H18BrNO2S, CAS 342378-65-8

5-(4-Bromophenyl)-2-(4-tert-butylphenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 342378-65-8C₂₂H₁₈BrNO₂S

5-(4-Bromophenyl)-2-(4-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C18H9BrFNO2S, CAS 312528-83-9

5-(4-Bromophenyl)-2-(4-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 312528-83-9C₁₈H₉BrFNO₂S

2-(4-tert-Butylphenyl)-5-(4-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C23H21NO2S, CAS 461436-25-9

2-(4-tert-Butylphenyl)-5-(4-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 461436-25-9C₂₃H₂₁NO₂S

5-(4-Bromophenyl)-2-(2-methylphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12BrNO2S, CAS 342382-87-0

5-(4-Bromophenyl)-2-(2-methylphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342382-87-0C₁₉H₁₂BrNO₂S

2-(4-tert-Butylphenyl)-5-phenyl-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C22H19NO2S, CAS 315694-10-1

2-(4-tert-Butylphenyl)-5-phenyl-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 315694-10-1C₂₂H₁₉NO₂S

2-(2-Bromophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12BrNO3S, CAS 312584-52-4

2-(2-Bromophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 312584-52-4C₁₉H₁₂BrNO₃S

5-(4-Chlorophenyl)-2-(2-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C18H9ClFNO2S, CAS 342382-47-2

5-(4-Chlorophenyl)-2-(2-fluorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 342382-47-2C₁₈H₉ClFNO₂S

2-(3-Bromophenyl)-5-phenylthieno[2,3-d][1,3]oxazin-4-one chemical structure, C18H10BrNO2S, CAS 312940-90-2

2-(3-Bromophenyl)-5-phenylthieno[2,3-d][1,3]oxazin-4-one

CAS 312940-90-2C₁₈H₁₀BrNO₂S

5-(4-Bromophenyl)-2-(4-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12BrNO2S, CAS 332017-56-8

5-(4-Bromophenyl)-2-(4-methylphenyl)thieno[2,3-d][1,3]oxazin-4-one

CAS 332017-56-8C₁₉H₁₂BrNO₂S

5-(4-Bromophenyl)-2-(3-chlorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C18H9BrClNO2S, CAS 312528-53-3

5-(4-Bromophenyl)-2-(3-chlorophenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 312528-53-3C₁₈H₉BrClNO₂S

2-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one chemical structure, C19H12ClNO3S, CAS 461430-91-1

2-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-thieno[2,3-d][1,3]oxazin-4-one

CAS 461430-91-1C₁₉H₁₂ClNO₃S