CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 13 atoms

83 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
83
With full pages
3
Scaffold SMILES

O=C1ON=CC1=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1ON=CC1=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 83 chemicals

(4Z)-4-Benzylidene-3-methylisoxazol-5(4H)-one chemical structure, C11H9NO2, CAS 36298-55-2
(4Z)-4-Benzylidene-3-methylisoxazol-5(4H)-one
CAS 36298-55-2C11H9NO2
5(4H)-Isoxazolone, 4-[(4-chlorophenyl)methylene]-3-methyl- chemical structure, C11H8ClNO2
5(4H)-Isoxazolone, 4-[(4-chlorophenyl)methylene]-3-methyl-
C11H8ClNO2
5(4H)-Isoxazolone, 4-[(2-methoxyphenyl)methylene]-3-methyl- chemical structure, C12H11NO3
5(4H)-Isoxazolone, 4-[(2-methoxyphenyl)methylene]-3-methyl-
C12H11NO3
5(4H)-Isoxazolone, 4-[(4-methoxyphenyl)methylene]-3-methyl- chemical structure, C12H11NO3, CAS 17975-46-1
5(4H)-Isoxazolone, 4-[(4-methoxyphenyl)methylene]-3-methyl-
CAS 17975-46-1C12H11NO3
5(4H)-Isoxazolone, 3-methyl-4-[(4-nitrophenyl)methylene]-, (Z)- chemical structure, C11H8N2O4, CAS 61588-02-1
5(4H)-Isoxazolone, 3-methyl-4-[(4-nitrophenyl)methylene]-, (Z)-
CAS 61588-02-1C11H8N2O4
(4Z)-4-[[4-(Diethylamino)phenyl]methylidene]-3-methyl-1,2-oxazol-5-one chemical structure, C15H18N2O2, CAS 452963-40-5
(4Z)-4-[[4-(Diethylamino)phenyl]methylidene]-3-methyl-1,2-oxazol-5-one
CAS 452963-40-5C15H18N2O2
4-[(2-Fluorophenyl)methylidene]-3-methyl-1,2-oxazol-5-one chemical structure, C11H8FNO2, CAS 6496-44-2
4-[(2-Fluorophenyl)methylidene]-3-methyl-1,2-oxazol-5-one
CAS 6496-44-2C11H8FNO2
(4Z)-4-[[4-(Dimethylamino)phenyl]methylidene]-3-methyl-1,2-oxazol-5-one chemical structure, C13H14N2O2, CAS 452963-42-7
(4Z)-4-[[4-(Dimethylamino)phenyl]methylidene]-3-methyl-1,2-oxazol-5-one
CAS 452963-42-7C13H14N2O2
(4Z)-4-[(3-Hydroxy-4-methoxyphenyl)methylidene]-3-methyl-1,2-oxazol-5-one chemical structure, C12H11NO4, CAS 312319-02-1
(4Z)-4-[(3-Hydroxy-4-methoxyphenyl)methylidene]-3-methyl-1,2-oxazol-5-one
CAS 312319-02-1C12H11NO4
2-Isoxazolin-5-one, 4-benzylidene-3-methyl- chemical structure, C11H9NO2, CAS 16430-09-4
2-Isoxazolin-5-one, 4-benzylidene-3-methyl-
CAS 16430-09-4C11H9NO2
4-(4-Chlorobenzylidene)-3-methylisoxazol-5(4H)-one chemical structure, C11H8ClNO2, CAS 17975-47-2
4-(4-Chlorobenzylidene)-3-methylisoxazol-5(4H)-one
CAS 17975-47-2C11H8ClNO2
(4E)-4-(2-Methoxybenzylidene)-3-methylisoxazol-5(4H)-one chemical structure, C12H11NO3, CAS 61365-95-5
(4E)-4-(2-Methoxybenzylidene)-3-methylisoxazol-5(4H)-one
CAS 61365-95-5C12H11NO3
(4Z)-3-Methyl-4-[(4-nitrophenyl)methylene]isoxazol-5-one chemical structure, C11H8N2O4
(4Z)-3-Methyl-4-[(4-nitrophenyl)methylene]isoxazol-5-one
C11H8N2O4
(4E)-4-Benzylidene-3-(chloromethyl)isoxazol-5(4H)-one chemical structure, C11H8ClNO2, CAS 1142198-85-3
(4E)-4-Benzylidene-3-(chloromethyl)isoxazol-5(4H)-one
CAS 1142198-85-3C11H8ClNO2
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one chemical structure, C11H7Cl2NO2, CAS 1142198-92-2
(4E)-4-(3-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one
CAS 1142198-92-2C11H7Cl2NO2
(4E)-4-(4-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one chemical structure, C11H7Cl2NO2, CAS 1142198-93-3
(4E)-4-(4-Chlorobenzylidene)-3-(chloromethyl)isoxazol-5(4H)-one
CAS 1142198-93-3C11H7Cl2NO2
(4E)-3-(Chloromethyl)-4-[(2,3-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one chemical structure, C13H12ClNO4, CAS 1142199-02-7
(4E)-3-(Chloromethyl)-4-[(2,3-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one
CAS 1142199-02-7C13H12ClNO4
(4E)-3-(Chloromethyl)-4-[(2,4-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one chemical structure, C13H12ClNO4, CAS 1142199-04-9
(4E)-3-(Chloromethyl)-4-[(2,4-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one
CAS 1142199-04-9C13H12ClNO4
(4E)-3-(Chloromethyl)-4-[(2,5-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one chemical structure, C13H12ClNO4, CAS 1142199-06-1
(4E)-3-(Chloromethyl)-4-[(2,5-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one
CAS 1142199-06-1C13H12ClNO4
(4E)-3-(Chloromethyl)-4-[(3,4-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one chemical structure, C13H12ClNO4, CAS 1142199-09-4
(4E)-3-(Chloromethyl)-4-[(3,4-dimethoxyphenyl)methylidene]-1,2-oxazol-5-one
CAS 1142199-09-4C13H12ClNO4
(4E)-3-(Chloromethyl)-4-[4-(dimethylamino)-benzylidene]isoxazol-5(4H)-one chemical structure, C13H13ClN2O2, CAS 1142199-10-7
(4E)-3-(Chloromethyl)-4-[4-(dimethylamino)-benzylidene]isoxazol-5(4H)-one
CAS 1142199-10-7C13H13ClN2O2
(4E)-3-(Chloromethyl)-4-(4-methoxybenzylidene)-isoxazol-5(4H)-one chemical structure, C12H10ClNO3, CAS 1142199-12-9
(4E)-3-(Chloromethyl)-4-(4-methoxybenzylidene)-isoxazol-5(4H)-one
CAS 1142199-12-9C12H10ClNO3
(4E)-3-(Chloromethyl)-4-(2-methoxybenzylidene)isoxazol-5(4H)-one chemical structure, C12H10ClNO3, CAS 1142199-13-0
(4E)-3-(Chloromethyl)-4-(2-methoxybenzylidene)isoxazol-5(4H)-one
CAS 1142199-13-0C12H10ClNO3
(4E)-3-(Chloromethyl)-4-(3-methoxybenzylidene)-isoxazol-5(4H)-one chemical structure, C12H10ClNO3
(4E)-3-(Chloromethyl)-4-(3-methoxybenzylidene)-isoxazol-5(4H)-one
C12H10ClNO3