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Murcko scaffold

Ring system with 2 rings and 11 atoms

73 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
73
With full pages
8
Scaffold SMILES

c1nnc(N2CCCCC2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nnc(N2CCCCC2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 73 chemicals

1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine chemical structure, C8H10F3N3S, CAS 694475-26-8
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine
CAS 694475-26-8C8H10F3N3S
5-Piperidin-1-yl-1,3,4-thiadiazol-2-amine chemical structure, C7H12N4S, CAS 71125-46-7
5-Piperidin-1-yl-1,3,4-thiadiazol-2-amine
CAS 71125-46-7C7H12N4S
5-(2-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine chemical structure, C8H14N4S, CAS 71125-47-8
5-(2-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine
CAS 71125-47-8C8H14N4S
5-(4-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine chemical structure, C8H14N4S, CAS 71125-48-9
5-(4-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine
CAS 71125-48-9C8H14N4S
5-(2,6-Dimethylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine chemical structure, C9H16N4S, CAS 71125-49-0
5-(2,6-Dimethylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine
CAS 71125-49-0C9H16N4S
5-(3-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine chemical structure, C8H14N4S, CAS 941867-25-0
5-(3-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine
CAS 941867-25-0C8H14N4S
Ethyl 1-(5-amino-1,3,4-thiadiazol-2-yl)piperidine-4-carboxylate chemical structure, C10H16N4O2S, CAS 897769-61-8
Ethyl 1-(5-amino-1,3,4-thiadiazol-2-yl)piperidine-4-carboxylate
CAS 897769-61-8C10H16N4O2S
1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-4-carboxylic acid chemical structure, C8H12N4O2S, CAS 923203-15-0
1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidine-4-carboxylic acid
CAS 923203-15-0C8H12N4O2S
2-[1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-2-yl]ethanol chemical structure, C9H16N4OS, CAS 941867-29-4
2-[1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-2-yl]ethanol
CAS 941867-29-4C9H16N4OS
1-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-(2-hydroxyethyl)piperidine chemical structure, C10H17N3OS, CAS 314064-66-9
1-(5-Methyl-1,3,4-thiadiazol-2-yl)-4-(2-hydroxyethyl)piperidine
CAS 314064-66-9C10H17N3OS
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carboxylic acid chemical structure, C9H10F3N3O2S, CAS 950603-35-7
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carboxylic acid
CAS 950603-35-7C9H10F3N3O2S
{1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl}methanol chemical structure, C9H12F3N3OS, CAS 950603-36-8
{1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl}methanol
CAS 950603-36-8C9H12F3N3OS
Ethyl 1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carboxylate chemical structure, C11H14F3N3O2S, CAS 950603-38-0
Ethyl 1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carboxylate
CAS 950603-38-0C11H14F3N3O2S
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carbaldehyde chemical structure, C9H10F3N3OS, CAS 958443-35-1
1-[5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidine-4-carbaldehyde
CAS 958443-35-1C9H10F3N3OS
N-Methyl-1-{1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl}methanamine chemical structure, C10H15F3N4S, CAS 958443-36-2
N-Methyl-1-{1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]piperidin-4-yl}methanamine
CAS 958443-36-2C10H15F3N4S
1-(1,3,4-Thiadiazol-2-yl)piperidin-4-ol chemical structure, C7H11N3OS, CAS 1344117-51-6
1-(1,3,4-Thiadiazol-2-yl)piperidin-4-ol
CAS 1344117-51-6C7H11N3OS
(1-(1,3,4-Thiadiazol-2-yl)piperidin-4-yl)methanamine chemical structure, C8H14N4S, CAS 1339187-84-6
(1-(1,3,4-Thiadiazol-2-yl)piperidin-4-yl)methanamine
CAS 1339187-84-6C8H14N4S
[1-(1,3,4-Thiadiazol-2-yl)piperidin-4-yl]methanol chemical structure, C8H13N3OS, CAS 1341373-11-2
[1-(1,3,4-Thiadiazol-2-yl)piperidin-4-yl]methanol
CAS 1341373-11-2C8H13N3OS
1-(1,3,4-Thiadiazol-2-yl)piperidine-4-carboxylic acid chemical structure, C8H11N3O2S, CAS 1408451-83-1
1-(1,3,4-Thiadiazol-2-yl)piperidine-4-carboxylic acid
CAS 1408451-83-1C8H11N3O2S
1-(1,3,4-Thiadiazol-2-yl)piperidin-4-amine chemical structure, C7H12N4S, CAS 1341425-33-9
1-(1,3,4-Thiadiazol-2-yl)piperidin-4-amine
CAS 1341425-33-9C7H12N4S
1-(5-Bromo-1,3,4-thiadiazol-2-yl)piperidine chemical structure, C7H10BrN3S, CAS 1357147-48-8
1-(5-Bromo-1,3,4-thiadiazol-2-yl)piperidine
CAS 1357147-48-8C7H10BrN3S
1-(5-Bromo-1,3,4-thiadiazol-2-yl)piperidin-4-ol chemical structure, C7H10BrN3OS, CAS 1020658-54-1
1-(5-Bromo-1,3,4-thiadiazol-2-yl)piperidin-4-ol
CAS 1020658-54-1C7H10BrN3OS
1-(5-Bromo-1,3,4-thiadiazol-2-yl)-N-methyl-4-piperidinecarboxamide chemical structure, C9H13BrN4OS, CAS 1341457-15-5
1-(5-Bromo-1,3,4-thiadiazol-2-yl)-N-methyl-4-piperidinecarboxamide
CAS 1341457-15-5C9H13BrN4OS
1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-4-ol chemical structure, C7H12N4OS, CAS 1020658-53-0
1-(5-Amino-1,3,4-thiadiazol-2-yl)piperidin-4-ol
CAS 1020658-53-0C7H12N4OS