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Murcko scaffold

Ring system with 1 ring and 8 atoms

21 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
21
With full pages
7
Scaffold SMILES

C=C1SC(=O)NC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1SC(=O)NC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

5-Isopropylidene-thiazolidine-2,4-dione chemical structure, C6H7NO2S, CAS 5835-47-2
5-Isopropylidene-thiazolidine-2,4-dione
CAS 5835-47-2C6H7NO2S
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)acetic acid chemical structure, C5H3NO4S
2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)acetic acid
C5H3NO4S
(5E)-3-Methyl-5-(3-methylbutylidene)-1,3-thiazolidine-2,4-dione chemical structure, C9H13NO2S, CAS 860610-45-3
(5E)-3-Methyl-5-(3-methylbutylidene)-1,3-thiazolidine-2,4-dione
CAS 860610-45-3C9H13NO2S
(Z)-2-(2-(2,4-Dioxothiazolidin-5-ylidene)acetamido)acetic acid chemical structure, C7H6N2O5S, CAS 638136-37-5
(Z)-2-(2-(2,4-Dioxothiazolidin-5-ylidene)acetamido)acetic acid
CAS 638136-37-5C7H6N2O5S
(Z)-Ethyl 2-(2,4-dioxothiazolidin-5-ylidene)acetate chemical structure, C7H7NO4S, CAS 1397692-43-1
(Z)-Ethyl 2-(2,4-dioxothiazolidin-5-ylidene)acetate
CAS 1397692-43-1C7H7NO4S
2-[(5E)-2,4-Dioxo-1,3-thiazolidin-5-ylidene]acetic acid chemical structure, C5H3NO4S, CAS 1639050-53-5
2-[(5E)-2,4-Dioxo-1,3-thiazolidin-5-ylidene]acetic acid
CAS 1639050-53-5C5H3NO4S
(Z)-2-(2,4-Dioxothiazolidin-5-ylidene)acetic acid chemical structure, C5H3NO4S, CAS 5374-29-8
(Z)-2-(2,4-Dioxothiazolidin-5-ylidene)acetic acid
CAS 5374-29-8C5H3NO4S
(2Z)-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-ylidene)acetic acid chemical structure, C8H9NO4S, CAS 613656-85-2
(2Z)-(2,4-Dioxo-3-propyl-1,3-thiazolidin-5-ylidene)acetic acid
CAS 613656-85-2C8H9NO4S
(2Z)-(3-Ethyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)acetic acid chemical structure, C7H7NO4S, CAS 613656-84-1
(2Z)-(3-Ethyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)acetic acid
CAS 613656-84-1C7H7NO4S
Methyl 2-(2,4-dioxo-1,3-thiazolidin-5-ylidene)acetate chemical structure, C6H5NO4S, CAS 41270-57-9
Methyl 2-(2,4-dioxo-1,3-thiazolidin-5-ylidene)acetate
CAS 41270-57-9C6H5NO4S
(E)-2-(3-Methyl-2,4-dioxothiazolidin-5-ylidene)acetic acid chemical structure, C6H5NO4S
(E)-2-(3-Methyl-2,4-dioxothiazolidin-5-ylidene)acetic acid
C6H5NO4S
2-(3-Methyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)acetic acid chemical structure, C6H5NO4S, CAS 90137-11-4
2-(3-Methyl-2,4-dioxo-1,3-thiazolidin-5-ylidene)acetic acid
CAS 90137-11-4C6H5NO4S
Acetic acid, (3-methyl-2,4-dioxo-5-thiazolidinylidene)- chemical structure, C6H5NO4S
Acetic acid, (3-methyl-2,4-dioxo-5-thiazolidinylidene)-
C6H5NO4S
(5Z)-5-Heptylidene-3-methyl-1,3-thiazolidine-2,4-dione chemical structure, C11H17NO2S, CAS 866040-35-9
(5Z)-5-Heptylidene-3-methyl-1,3-thiazolidine-2,4-dione
CAS 866040-35-9C11H17NO2S
(5Z)-5-(Dimethylaminomethylidene)-3-methylsulfonyl-1,3-thiazolidine-2,4-dione chemical structure, C7H10N2O4S2, CAS 866136-89-2
(5Z)-5-(Dimethylaminomethylidene)-3-methylsulfonyl-1,3-thiazolidine-2,4-dione
CAS 866136-89-2C7H10N2O4S2
5-[(Z)-(Dimethylamino)methylidene]-3-methyl-1,3-thiazolane-2,4-dione chemical structure, C7H10N2O2S, CAS 5272-47-9
5-[(Z)-(Dimethylamino)methylidene]-3-methyl-1,3-thiazolane-2,4-dione
CAS 5272-47-9C7H10N2O2S
(Z)-Isopropyl 2-(2,4-dioxothiazolidin-5-ylidene)acetate chemical structure, C8H9NO4S, CAS 610261-11-5
(Z)-Isopropyl 2-(2,4-dioxothiazolidin-5-ylidene)acetate
CAS 610261-11-5C8H9NO4S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-hydroxyethyl)acetamide chemical structure, C7H8N2O4S
(2Z)-2-(2,4-Dioxo-1,3-thiazolidin-5-ylidene)-N-(2-hydroxyethyl)acetamide
C7H8N2O4S
2-[(2,4-Dioxo-5-thiazolidinylidene)methoxy]acetic acid chemical structure, C6H5NO5S, CAS 123021-86-3
2-[(2,4-Dioxo-5-thiazolidinylidene)methoxy]acetic acid
CAS 123021-86-3C6H5NO5S
Acetamide, 2-(2,4-dioxo-5-thiazolidinylidene)-N-(2-hydroxyethyl)- chemical structure, C7H8N2O4S, CAS 464900-87-6
Acetamide, 2-(2,4-dioxo-5-thiazolidinylidene)-N-(2-hydroxyethyl)-
CAS 464900-87-6C7H8N2O4S
Acetamide,2-(2,4-dioxo-5-thiazolidinylidene)-N-(2-hydroxyethyl)- chemical structure, C7H8N2O4S
Acetamide,2-(2,4-dioxo-5-thiazolidinylidene)-N-(2-hydroxyethyl)-
C7H8N2O4S