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Murcko scaffold

Ring system with 3 rings and 21 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
5
With full pages
0
Scaffold SMILES

O=C(Cc1ccc(-c2ccccc2)cc1)Nc1nccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccc(-c2ccccc2)cc1)Nc1nccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

N-Methyl-N-(4-methyl-5-sulfamoyl-thiazol-2-yl)-2-(4-phenylphenyl)acetamide chemical structure, C19H19N3O3S2, CAS 348086-70-4
N-Methyl-N-(4-methyl-5-sulfamoyl-thiazol-2-yl)-2-(4-phenylphenyl)acetamide
CAS 348086-70-4C19H19N3O3S2
2-(2-Fluorobiphenyl-4-yl)-N-(1,3-thiazol-2-yl)propanamide chemical structure, C18H15FN2OS, CAS 921114-72-9
2-(2-Fluorobiphenyl-4-yl)-N-(1,3-thiazol-2-yl)propanamide
CAS 921114-72-9C18H15FN2OS
Orb1944086 chemical structure, C20H19F2N3O2S2, CAS 2305750-23-4
Orb1944086
CAS 2305750-23-4C20H19F2N3O2S2
Adibelivir hydrochloride chemical structure, C20H20ClF2N3O2S2, CAS 2954725-84-7
Adibelivir hydrochloride
CAS 2954725-84-7C20H20ClF2N3O2S2
Orb3236681 chemical structure, C20H20ClF2N3O2S2
Orb3236681
C20H20ClF2N3O2S2