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Murcko scaffold

2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro- scaffold

77 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
77
With full pages
6
Scaffold SMILES

O=C1Cc2ccccc2CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro- page
Murcko scaffold O=C1Cc2ccccc2CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro- chemical structure, C10H11NO, CAS 15987-50-5
2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-
CAS 15987-50-5C10H11NO
2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-3-(3-(dimethylamino)propyl)-, monohydrochloride chemical structure, C15H23ClN2O, CAS 20904-21-6
2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-3-(3-(dimethylamino)propyl)-, monohydrochloride
CAS 20904-21-6C15H23ClN2O
2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-1,5,7,8-tetrahydroxy- chemical structure, C10H11NO5, CAS 23824-39-7
2H-3-Benzazepin-2-one, 1,3,4,5-tetrahydro-1,5,7,8-tetrahydroxy-
CAS 23824-39-7C10H11NO5
2,3,4,5-Tetrahydro-8-hydroxy-4-oxo-1H-3-benzazepine-2-carboxylic acid chemical structure, C11H11NO4, CAS 17639-47-3
2,3,4,5-Tetrahydro-8-hydroxy-4-oxo-1H-3-benzazepine-2-carboxylic acid
CAS 17639-47-3C11H11NO4
1H-3-Benzazepine-2-carboxylic acid, 2,3,4,5-tetrahydro-8-methoxy-4-oxo-, methyl ester chemical structure, C13H15NO4, CAS 17639-49-5
1H-3-Benzazepine-2-carboxylic acid, 2,3,4,5-tetrahydro-8-methoxy-4-oxo-, methyl ester
CAS 17639-49-5C13H15NO4
3-Methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one chemical structure, C11H13NO, CAS 73644-95-8
3-Methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
CAS 73644-95-8C11H13NO
Semagacestat chemical structure, C19H27N3O4, CAS 425386-60-3
Semagacestat
CAS 425386-60-3C19H27N3O4
7,8-Dimethoxy-3-[3-(methylamino)propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one chemical structure, C16H24N2O3, CAS 85175-77-5
7,8-Dimethoxy-3-[3-(methylamino)propyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CAS 85175-77-5C16H24N2O3
7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one chemical structure, C12H15NO3, CAS 20925-64-8
7,8-Dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one
CAS 20925-64-8C12H15NO3
8-Chloro-1-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one chemical structure, C11H12ClNO, CAS 824430-77-5
8-Chloro-1-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
CAS 824430-77-5C11H12ClNO
7-Hydroxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one chemical structure, C10H11NO2, CAS 17639-44-0
7-Hydroxy-1,3,4,5-tetrahydro-benzo[d]azepin-2-one
CAS 17639-44-0C10H11NO2
3-Methyl-5-propyl-2,5-dihydro-1H-3-benzazepin-4-one chemical structure, C14H19NO, CAS 73644-96-9
3-Methyl-5-propyl-2,5-dihydro-1H-3-benzazepin-4-one
CAS 73644-96-9C14H19NO
(2-Oxo-2,3,4,5-tetrahydro-1H-benzo[D]azepin-1-yl)-carbamic acid methyl ester chemical structure, C12H14N2O3, CAS 74581-23-0
(2-Oxo-2,3,4,5-tetrahydro-1H-benzo[D]azepin-1-yl)-carbamic acid methyl ester
CAS 74581-23-0C12H14N2O3
Carbamic acid, (2,3,4,5-tetrahydro-7,8-dimethoxy-2-oxo-1H-3-benzazepin-1-yl)-, methyl ester chemical structure, C14H18N2O5, CAS 74581-24-1
Carbamic acid, (2,3,4,5-tetrahydro-7,8-dimethoxy-2-oxo-1H-3-benzazepin-1-yl)-, methyl ester
CAS 74581-24-1C14H18N2O5
3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one chemical structure, C15H20ClNO3, CAS 85175-65-1
3-(3-Chloropropyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CAS 85175-65-1C15H20ClNO3
7,8-Dimethoxy-3-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride chemical structure, C16H25ClN2O3, CAS 85175-52-6
7,8-Dimethoxy-3-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride
CAS 85175-52-6C16H25ClN2O3
8-Methoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one chemical structure, C11H13NO2, CAS 37682-06-7
8-Methoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CAS 37682-06-7C11H13NO2
7-Bromo-8-methoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one chemical structure, C11H12BrNO2, CAS 96254-74-9
7-Bromo-8-methoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CAS 96254-74-9C11H12BrNO2
7-Methoxy-4,5-dihydro-1H-benzo[D]azepin-2(3H)-one chemical structure, C11H13NO2, CAS 17639-45-1
7-Methoxy-4,5-dihydro-1H-benzo[D]azepin-2(3H)-one
CAS 17639-45-1C11H13NO2
8-Methoxy-7-nitro-1,3,4,5-tetrahydro-benzo[d]azepin-2-one chemical structure, C11H12N2O4, CAS 96254-54-5
8-Methoxy-7-nitro-1,3,4,5-tetrahydro-benzo[d]azepin-2-one
CAS 96254-54-5C11H12N2O4
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-8-methoxy-2H-3-benzazepin-2-one chemical structure, C14H18ClNO2, CAS 85175-86-6
3-(3-Chloropropyl)-1,3,4,5-tetrahydro-8-methoxy-2H-3-benzazepin-2-one
CAS 85175-86-6C14H18ClNO2
1-Chloro-4,4-dimethyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one chemical structure, C12H14ClNO, CAS 184590-72-5
1-Chloro-4,4-dimethyl-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one
CAS 184590-72-5C12H14ClNO
8-Methoxy-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one chemical structure, C12H15NO2, CAS 118616-04-9
8-Methoxy-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
CAS 118616-04-9C12H15NO2
1-Amino-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one chemical structure, C11H14N2O, CAS 253324-91-3
1-Amino-3-methyl-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one
CAS 253324-91-3C11H14N2O