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Murcko scaffold

Ring system with 2 rings and 16 atoms

15 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 16
Chemicals: 15
With full pages: 3

Scaffold SMILES

O=C(C=Cc1ccccn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(C=Cc1ccccn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1-(2-Hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one chemical structure, C14H11NO2, CAS 2875-24-3

1-(2-Hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one

CAS 2875-24-3C₁₄H₁₁NO₂

WR-190433 chemical structure, C14H11NO, CAS 5325-66-6

CAS 5325-66-6C₁₄H₁₁NO

4'-Amino-3-(2-pyridyl)acrylophenone chemical structure, C14H12N2O, CAS 5325-89-3

4'-Amino-3-(2-pyridyl)acrylophenone

CAS 5325-89-3C₁₄H₁₂N₂O

4'-Chloro-3-(2-pyridyl)acrylophenone chemical structure, C14H10ClNO, CAS 5337-52-0

4'-Chloro-3-(2-pyridyl)acrylophenone

CAS 5337-52-0C₁₄H₁₀ClNO

1-(5-Chloro-2-hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one chemical structure, C14H10ClNO2, CAS 5250-17-9

1-(5-Chloro-2-hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one

CAS 5250-17-9C₁₄H₁₀ClNO₂

(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-pyridin-2-ylprop-2-en-1-one chemical structure, C15H13NO3, CAS 6344-90-7

(E)-1-(2-Hydroxy-4-methoxyphenyl)-3-pyridin-2-ylprop-2-en-1-one

CAS 6344-90-7C₁₅H₁₃NO₃

1-(4-Methoxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one chemical structure, C15H13NO2, CAS 71858-72-5

1-(4-Methoxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one

CAS 71858-72-5C₁₅H₁₃NO₂

(E)-1-(3-Chloro-2-hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one chemical structure, C14H10ClNO2, CAS 720676-82-4

(E)-1-(3-Chloro-2-hydroxyphenyl)-3-pyridin-2-ylprop-2-en-1-one

CAS 720676-82-4C₁₄H₁₀ClNO₂

(E)-1-(3,5-Dichloro-2-hydroxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one chemical structure, C14H9Cl2NO2, CAS 5289-99-6

(E)-1-(3,5-Dichloro-2-hydroxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one

CAS 5289-99-6C₁₄H₉Cl₂NO₂

3-(6-Carbamoyl-2-pyridyl)-1-phenyl-2-propen-1-one chemical structure, C15H12N2O2, CAS 132390-69-3

3-(6-Carbamoyl-2-pyridyl)-1-phenyl-2-propen-1-one

CAS 132390-69-3C₁₅H₁₂N₂O₂

1-(2-Bromophenyl)-3-(pyridin-2-yl)prop-2-en-1-one chemical structure, C14H10BrNO, CAS 104061-74-7

1-(2-Bromophenyl)-3-(pyridin-2-yl)prop-2-en-1-one

CAS 104061-74-7C₁₄H₁₀BrNO

1-(4-Nitrophenyl)-3-(pyridin-2-yl)prop-2-en-1-one chemical structure, C14H10N2O3, CAS 18096-97-4

1-(4-Nitrophenyl)-3-(pyridin-2-yl)prop-2-en-1-one

CAS 18096-97-4C₁₄H₁₀N₂O₃

1-(3-Methoxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one chemical structure, C15H13NO2, CAS 104061-75-8

1-(3-Methoxyphenyl)-3-(pyridin-2-yl)prop-2-en-1-one

CAS 104061-75-8C₁₅H₁₃NO₂

1-(4-Fluorophenyl)-3-(6-methylpyridin-2-yl)prop-2-en-1-one chemical structure, C15H12FNO, CAS 61864-66-2

1-(4-Fluorophenyl)-3-(6-methylpyridin-2-yl)prop-2-en-1-one

CAS 61864-66-2C₁₅H₁₂FNO

(E)-1-[2,4-Dimethoxy-5-(3-methylbut-2-enyl)phenyl]-3-pyridin-2-ylprop-2-en-1-one chemical structure, C21H23NO3, CAS 3085517-19-4

(E)-1-[2,4-Dimethoxy-5-(3-methylbut-2-enyl)phenyl]-3-pyridin-2-ylprop-2-en-1-one

CAS 3085517-19-4C₂₁H₂₃NO₃