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Murcko scaffold

2-(Piperidin-4-yl)-1H-1,3-benzodiazole scaffold

90 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
90
With full pages
9
Scaffold SMILES

c1ccc2[nH]c(C3CCNCC3)nc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperidin-4-yl)-1H-1,3-benzodiazole page
Murcko scaffold c1ccc2[nH]c(C3CCNCC3)nc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

5,6-Dichloro-2-(piperidin-4-yl)-1H-1,3-benzodiazole chemical structure, C12H13Cl2N3, CAS 578708-01-7
5,6-Dichloro-2-(piperidin-4-yl)-1H-1,3-benzodiazole
CAS 578708-01-7C12H13Cl2N3
1H-Benzimidazole, 5,6-dichloro-1-ethyl-2-(4-piperidinyl)- chemical structure, C14H17Cl2N3, CAS 578708-02-8
1H-Benzimidazole, 5,6-dichloro-1-ethyl-2-(4-piperidinyl)-
CAS 578708-02-8C14H17Cl2N3
2-(Piperidin-4-yl)-1H-1,3-benzodiazole chemical structure, C12H15N3, CAS 38385-95-4
2-(Piperidin-4-yl)-1H-1,3-benzodiazole
CAS 38385-95-4C12H15N3
6-Nitro-2-piperidin-4-yl-1H-benzimidazole chemical structure, C12H14N4O2, CAS 521298-40-8
6-Nitro-2-piperidin-4-yl-1H-benzimidazole
CAS 521298-40-8C12H14N4O2
Ethyl N-{[4-(1H-benzimidazol-2-yl)piperidin-1-yl]carbonothioyl}glycinate chemical structure, C17H22N4O2S, CAS 590378-28-2
Ethyl N-{[4-(1H-benzimidazol-2-yl)piperidin-1-yl]carbonothioyl}glycinate
CAS 590378-28-2C17H22N4O2S
1-Piperidinecarbothioamide, 4-(1H-benzimidazol-2-yl)-N-propyl- chemical structure, C16H22N4S, CAS 605629-33-2
1-Piperidinecarbothioamide, 4-(1H-benzimidazol-2-yl)-N-propyl-
CAS 605629-33-2C16H22N4S
1-Piperidinecarbothioamide, 4-(5,6-dimethyl-1H-benzimidazol-2-yl)-N-propyl- chemical structure, C18H26N4S, CAS 605629-36-5
1-Piperidinecarbothioamide, 4-(5,6-dimethyl-1H-benzimidazol-2-yl)-N-propyl-
CAS 605629-36-5C18H26N4S
4-(1H-Benzimidazol-2-yl)-N-prop-2-enylpiperidine-1-carbothioamide chemical structure, C16H20N4S, CAS 606083-65-2
4-(1H-Benzimidazol-2-yl)-N-prop-2-enylpiperidine-1-carbothioamide
CAS 606083-65-2C16H20N4S
4-(5,6-Dimethyl-1H-benzimidazol-2-yl)-N-prop-2-enylpiperidine-1-carbothioamide chemical structure, C18H24N4S, CAS 606083-67-4
4-(5,6-Dimethyl-1H-benzimidazol-2-yl)-N-prop-2-enylpiperidine-1-carbothioamide
CAS 606083-67-4C18H24N4S
1-Piperidinecarbothioamide, 4-(5,6-dimethyl-1H-benzimidazol-2-yl)-N-[3-(1-methylethoxy)propyl]- chemical structure, C21H32N4OS, CAS 606083-71-0
1-Piperidinecarbothioamide, 4-(5,6-dimethyl-1H-benzimidazol-2-yl)-N-[3-(1-methylethoxy)propyl]-
CAS 606083-71-0C21H32N4OS
1-Piperidinecarboxamide, 4-(1H-benzimidazol-2-yl)-N-propyl- chemical structure, C16H22N4O, CAS 606083-72-1
1-Piperidinecarboxamide, 4-(1H-benzimidazol-2-yl)-N-propyl-
CAS 606083-72-1C16H22N4O
1-Piperidinecarboxamide, 4-(5-methyl-1H-benzimidazol-2-yl)-N-propyl- chemical structure, C17H24N4O, CAS 606083-74-3
1-Piperidinecarboxamide, 4-(5-methyl-1H-benzimidazol-2-yl)-N-propyl-
CAS 606083-74-3C17H24N4O
1-Piperidinecarboxamide, 4-(5-chloro-1H-benzimidazol-2-yl)-N-propyl- chemical structure, C16H21ClN4O, CAS 606083-75-4
1-Piperidinecarboxamide, 4-(5-chloro-1H-benzimidazol-2-yl)-N-propyl-
CAS 606083-75-4C16H21ClN4O
1-Methyl-2-piperidin-4-yl-1H-benzoimidazole chemical structure, C13H17N3, CAS 180160-86-5
1-Methyl-2-piperidin-4-yl-1H-benzoimidazole
CAS 180160-86-5C13H17N3
2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide chemical structure, C16H22N4O, CAS 272769-49-0
2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide
CAS 272769-49-0C16H22N4O
2-(1-Methyl-4-piperidyl)benzimidazole chemical structure, C13H17N3, CAS 51784-76-0
2-(1-Methyl-4-piperidyl)benzimidazole
CAS 51784-76-0C13H17N3
1-(2-Ethoxyethyl)-2-(1-methyl-4-piperidyl)benzimidazole chemical structure, C17H25N3O, CAS 110963-55-8
1-(2-Ethoxyethyl)-2-(1-methyl-4-piperidyl)benzimidazole
CAS 110963-55-8C17H25N3O
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole chemical structure, C16H23N3O, CAS 110963-63-8
1-(2-Ethoxyethyl)-2-(piperidin-4-yl)-1H-benzo[d]imidazole
CAS 110963-63-8C16H23N3O
1-[4-(1H-Benzimidazol-2-yl)piperidin-1-yl]-2-ethylbutan-1-one chemical structure, C18H25N3O, CAS 919057-24-2
1-[4-(1H-Benzimidazol-2-yl)piperidin-1-yl]-2-ethylbutan-1-one
CAS 919057-24-2C18H25N3O
6-Chloro-2-(piperidin-4-yl)-1H-benzo[D]imidazole chemical structure, C12H14ClN3, CAS 578709-06-5
6-Chloro-2-(piperidin-4-yl)-1H-benzo[D]imidazole
CAS 578709-06-5C12H14ClN3
5-Methyl-2-piperidin-4-yl-1H-benzoimidazole dihydrochloride chemical structure, C13H19Cl2N3, CAS 1054552-13-4
5-Methyl-2-piperidin-4-yl-1H-benzoimidazole dihydrochloride
CAS 1054552-13-4C13H19Cl2N3
5-Methyl-2-piperidin-4-yl-1H-benzoimidazole chemical structure, C13H17N3, CAS 295790-48-6
5-Methyl-2-piperidin-4-yl-1H-benzoimidazole
CAS 295790-48-6C13H17N3
Methyl N-{[4-(1H-benzimidazol-2-yl)piperidin-1-yl]carbonyl}glycinate chemical structure, C16H20N4O3, CAS 929839-54-3
Methyl N-{[4-(1H-benzimidazol-2-yl)piperidin-1-yl]carbonyl}glycinate
CAS 929839-54-3C16H20N4O3
4-(1H-Benzo[d]imidazol-2-yl)-N,N-dimethylpiperidine-1-sulfonamide chemical structure, C14H20N4O2S, CAS 887886-66-0
4-(1H-Benzo[d]imidazol-2-yl)-N,N-dimethylpiperidine-1-sulfonamide
CAS 887886-66-0C14H20N4O2S