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Murcko scaffold

Ring system with 2 rings and 8 atoms

28 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 8
Chemicals: 28
With full pages: 6

Scaffold SMILES

O=C1CC2SC=CN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1CC2SC=CN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

Ritipenem chemical structure, C10H12N2O6S, CAS 84845-57-8

CAS 84845-57-8C₁₀H₁₂N₂O₆S

Sch 34343 chemical structure, C11H14N2O6S2, CAS 95415-91-1

CAS 95415-91-1C₁₁H₁₄N₂O₆S₂

(5R,6S)-3-(Aminomethyl)-6-((1R)-1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid chemical structure, C9H12N2O4S, CAS 107740-67-0

(5R,6S)-3-(Aminomethyl)-6-((1R)-1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid

CAS 107740-67-0C₉H₁₂N₂O₄S

2-(2-Fluoroethylthio)-6-(1-hydroxyethyl)penem-3-carboxylate chemical structure, C8H9NO4S, CAS 91685-69-7

2-(2-Fluoroethylthio)-6-(1-hydroxyethyl)penem-3-carboxylate

CAS 91685-69-7C₈H₉NO₄S

(Acetyloxy)methyl 6-(1-hydroxyethyl)-3-((hydroxy(imino)methoxy)methyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate chemical structure, C13H16N2O8S, CAS 99376-22-4

(Acetyloxy)methyl 6-(1-hydroxyethyl)-3-((hydroxy(imino)methoxy)methyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate

CAS 99376-22-4C₁₃H₁₆N₂O₈S

Sch 33755 chemical structure, C10H14N2O4S2, CAS 72888-55-2

CAS 72888-55-2C₁₀H₁₄N₂O₄S₂

(Acetyloxy)methyl (5R,6S)-3-(((aminocarbonyl)oxy)methyl)-6-((1R)-1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate chemical structure, C13H16N2O8S, CAS 87238-52-6

(Acetyloxy)methyl (5R,6S)-3-(((aminocarbonyl)oxy)methyl)-6-((1R)-1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate

CAS 87238-52-6C₁₃H₁₆N₂O₈S

(5R)-3-Methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C7H7NO3S, CAS 69126-89-2

(5R)-3-Methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 69126-89-2C₇H₇NO₃S

Sch 29482 chemical structure, C10H13NO4S2, CAS 77646-83-4

CAS 77646-83-4C₁₀H₁₃NO₄S₂

(5R,6S)-3-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C11H14N2O6S2, CAS 92008-67-8

(5R,6S)-3-[(2S)-2-Amino-2-carboxyethyl]sulfanyl-6-[(1R)-1-hydroxyethyl]-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 92008-67-8C₁₁H₁₄N₂O₆S₂

(5S)-7-Oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C6H5NO3S, CAS 69126-85-8

(5S)-7-Oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 69126-85-8C₆H₅NO₃S

(5R)-7-Oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C6H5NO3S, CAS 69126-94-9

(5R)-7-Oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 69126-94-9C₆H₅NO₃S

3-{[(2-Aminoethyl)sulfanyl]methyl}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C9H12N2O3S2, CAS 79598-61-1

3-{[(2-Aminoethyl)sulfanyl]methyl}-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 79598-61-1C₉H₁₂N₂O₃S₂

Ritipenem sodium chemical structure, C10H11N2NaO6S, CAS 84845-58-9

Ritipenem sodium

CAS 84845-58-9C₁₀H₁₁N₂NaO₆S

SCH34343 sodium chemical structure, C11H13N2NaO6S2, CAS 94392-35-5

SCH34343 sodium

CAS 94392-35-5C₁₁H₁₃N₂NaO₆S₂

Sodium (5R-(5alpha,6alpha(R*)))-3-(ethylthio)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate chemical structure, C10H12NNaO4S2, CAS 77646-84-5

Sodium (5R-(5alpha,6alpha(R*)))-3-(ethylthio)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylate

CAS 77646-84-5C₁₀H₁₂NNaO₄S₂

Penem chemical structure, C5H5NOS, CAS 83961-74-4

CAS 83961-74-4C₅H₅NOS

Sch 33440 chemical structure, C11H16N2O4S2, CAS 81036-52-4

CAS 81036-52-4C₁₁H₁₆N₂O₄S₂

6-alpha-Hydroxyethyl-2-acetoxymethyl-2-penem-3-carboxylic acid chemical structure, C11H13NO6S, CAS 83572-65-0

6-alpha-Hydroxyethyl-2-acetoxymethyl-2-penem-3-carboxylic acid

CAS 83572-65-0C₁₁H₁₃NO₆S

Allyl [5R-[5alpha,6alpha(R*)]]-3-(ethylthio)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate chemical structure, C13H17NO4S2, CAS 76496-44-1

Allyl [5R-[5alpha,6alpha(R*)]]-3-(ethylthio)-6-(1-hydroxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

CAS 76496-44-1C₁₃H₁₇NO₄S₂

(5R,6R)-6-Amino-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C7H8N2O3S, CAS 64195-73-9

(5R,6R)-6-Amino-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 64195-73-9C₇H₈N₂O₃S

(5S,6R)-3-Ethyl-6-hydroxy-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C8H9NO4S

(5S,6R)-3-Ethyl-6-hydroxy-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

(5S,6R)-6-Acetyl-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid chemical structure, C9H9NO4S, CAS 784999-23-1

(5S,6R)-6-Acetyl-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

CAS 784999-23-1C₉H₉NO₄S

RefChem:296461 chemical structure, C20H33NO4S2Si, CAS 93603-76-0

CAS 93603-76-0C₂₀H₃₃NO₄S₂Si