CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

21 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
21
With full pages
7
Scaffold SMILES

S=C(Nc1ccccc1)NN1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=C(Nc1ccccc1)NN1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

1-(4-Fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H17FN4S, CAS 297160-54-4
1-(4-Fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 297160-54-4C12H17FN4S
1-(4-Chloro-2-methylphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C13H19ClN4S, CAS 444285-26-1
1-(4-Chloro-2-methylphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 444285-26-1C13H19ClN4S
1-(2,3-Dimethylphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C14H22N4S, CAS 326015-96-7
1-(2,3-Dimethylphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 326015-96-7C14H22N4S
1-(3,5-Dimethoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C14H22N4O2S, CAS 443664-31-1
1-(3,5-Dimethoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 443664-31-1C14H22N4O2S
(E)-N'-(2,5-Dimethoxyphenyl)-N-(4-methylpiperazin-1-yl)carbamimidothioic acid chemical structure, C14H22N4O2S, CAS 326016-23-3
(E)-N'-(2,5-Dimethoxyphenyl)-N-(4-methylpiperazin-1-yl)carbamimidothioic acid
CAS 326016-23-3C14H22N4O2S
1-(3-Fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H17FN4S, CAS 757195-98-5
1-(3-Fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 757195-98-5C12H17FN4S
1-(2-Methoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C13H20N4OS, CAS 491639-80-6
1-(2-Methoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 491639-80-6C13H20N4OS
1-(3-Methylphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C13H20N4S, CAS 326015-62-7
1-(3-Methylphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 326015-62-7C13H20N4S
1-(2,4-Dichlorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H16Cl2N4S, CAS 405067-94-9
1-(2,4-Dichlorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 405067-94-9C12H16Cl2N4S
1-(3-Methoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C13H20N4OS, CAS 482301-01-9
1-(3-Methoxyphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 482301-01-9C13H20N4OS
4-({[(4-Methylpiperazin-1-yl)amino]carbonothioyl}amino)benzenesulfonamide chemical structure, C12H19N5O2S2, CAS 664969-63-5
4-({[(4-Methylpiperazin-1-yl)amino]carbonothioyl}amino)benzenesulfonamide
CAS 664969-63-5C12H19N5O2S2
1-(2,3-Dichlorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H16Cl2N4S, CAS 708238-51-1
1-(2,3-Dichlorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 708238-51-1C12H16Cl2N4S
1-(4-Methylpiperazin-1-yl)-3-[4-(propan-2-yl)phenyl]thiourea chemical structure, C15H24N4S, CAS 502879-29-0
1-(4-Methylpiperazin-1-yl)-3-[4-(propan-2-yl)phenyl]thiourea
CAS 502879-29-0C15H24N4S
1-(3-Chloro-4-fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H16ClFN4S, CAS 725220-78-0
1-(3-Chloro-4-fluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 725220-78-0C12H16ClFN4S
1-(4-Bromophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H17BrN4S, CAS 31204-36-1
1-(4-Bromophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 31204-36-1C12H17BrN4S
1-(4-Butylphenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C16H26N4S, CAS 692771-63-4
1-(4-Butylphenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 692771-63-4C16H26N4S
1-[4-(Difluoromethoxy)phenyl]-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C13H18F2N4OS, CAS 454210-17-4
1-[4-(Difluoromethoxy)phenyl]-3-(4-methylpiperazin-1-yl)thiourea
CAS 454210-17-4C13H18F2N4OS
1-(4-Methylpiperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)thiourea chemical structure, C15H24N4O3S, CAS 890174-42-2
1-(4-Methylpiperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)thiourea
CAS 890174-42-2C15H24N4O3S
1-(3,5-Difluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea chemical structure, C12H16F2N4S, CAS 838898-94-5
1-(3,5-Difluorophenyl)-3-(4-methylpiperazin-1-yl)thiourea
CAS 838898-94-5C12H16F2N4S
1-(4-Methylpiperazin-1-yl)-3-(4-nitrophenyl)thiourea chemical structure, C12H17N5O2S, CAS 6092-07-5
1-(4-Methylpiperazin-1-yl)-3-(4-nitrophenyl)thiourea
CAS 6092-07-5C12H17N5O2S
N-(4-Butoxyphenyl)-N'-(4-methylpiperazin-1-yl)thiourea chemical structure, C16H26N4OS, CAS 28439-87-4
N-(4-Butoxyphenyl)-N'-(4-methylpiperazin-1-yl)thiourea
CAS 28439-87-4C16H26N4OS