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Murcko scaffold

Ring system with 4 rings and 26 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
4
With full pages
1
Scaffold SMILES

O=C(Nc1ccccc1)C1NCC(c2ccccc2)C1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1NCC(c2ccccc2)C1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Methyl 4-((2r,3s,4r,5s)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoate chemical structure, C32H31Cl2F2N3O4, CAS 1229705-05-8
Methyl 4-((2r,3s,4r,5s)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoate
CAS 1229705-05-8C32H31Cl2F2N3O4
Idasanutlin chemical structure, C31H29Cl2F2N3O4, CAS 1229705-06-9
Idasanutlin
CAS 1229705-06-9C31H29Cl2F2N3O4
Idasanutlin (enantiomer) chemical structure, C31H29Cl2F2N3O4, CAS 2994298-12-1
Idasanutlin (enantiomer)
CAS 2994298-12-1C31H29Cl2F2N3O4
Ethyl 4-[[(4R)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoate chemical structure, C33H33Cl2F2N3O4, CAS 2034194-95-9
Ethyl 4-[[(4R)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoate
CAS 2034194-95-9C33H33Cl2F2N3O4