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Murcko scaffold

2-N,6-N-diphenylpyridine-2,6-dicarboxamide scaffold

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
25
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(C(=O)Nc2ccccc2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-N,6-N-diphenylpyridine-2,6-dicarboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1cccc(C(=O)Nc2ccccc2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Pyridine-2,6-dicarboxamide, N,N'-bis(3-trifluoromethylphenyl)- chemical structure, C21H13F6N3O2, CAS 312592-76-0
Pyridine-2,6-dicarboxamide, N,N'-bis(3-trifluoromethylphenyl)-
CAS 312592-76-0C21H13F6N3O2
N2,N6-Bis(2-methylphenyl)-2,6-pyridinedicarboxamide chemical structure, C21H19N3O2, CAS 335215-65-1
N2,N6-Bis(2-methylphenyl)-2,6-pyridinedicarboxamide
CAS 335215-65-1C21H19N3O2
2-N,6-N-bis(2,6-dimethylphenyl)pyridine-2,6-dicarboxamide chemical structure, C23H23N3O2, CAS 438454-86-5
2-N,6-N-bis(2,6-dimethylphenyl)pyridine-2,6-dicarboxamide
CAS 438454-86-5C23H23N3O2
2-N,6-N-bis(5-chloro-2-methoxyphenyl)pyridine-2,6-dicarboxamide chemical structure, C21H17Cl2N3O4, CAS 547720-42-3
2-N,6-N-bis(5-chloro-2-methoxyphenyl)pyridine-2,6-dicarboxamide
CAS 547720-42-3C21H17Cl2N3O4
2-N,6-N-diphenylpyridine-2,6-dicarboxamide chemical structure, C19H15N3O2, CAS 61414-14-0
2-N,6-N-diphenylpyridine-2,6-dicarboxamide
CAS 61414-14-0C19H15N3O2
2-N,6-N-bis(2-carbamoylphenyl)pyridine-2,6-dicarboxamide chemical structure, C21H17N5O4, CAS 548466-91-7
2-N,6-N-bis(2-carbamoylphenyl)pyridine-2,6-dicarboxamide
CAS 548466-91-7C21H17N5O4
Propyl 4-[[6-[(4-propoxycarbonylphenyl)carbamoyl]pyridine-2-carbonyl]amino]benzoate chemical structure, C27H27N3O6, CAS 547750-93-6
Propyl 4-[[6-[(4-propoxycarbonylphenyl)carbamoyl]pyridine-2-carbonyl]amino]benzoate
CAS 547750-93-6C27H27N3O6
N,N'-Bis(2,6-diethylphenyl)pyridine-2,6-dicarboxamide chemical structure, C27H31N3O2, CAS 548787-99-1
N,N'-Bis(2,6-diethylphenyl)pyridine-2,6-dicarboxamide
CAS 548787-99-1C27H31N3O2
2-N,6-N-bis(2-ethylphenyl)pyridine-2,6-dicarboxamide chemical structure, C23H23N3O2, CAS 547748-89-0
2-N,6-N-bis(2-ethylphenyl)pyridine-2,6-dicarboxamide
CAS 547748-89-0C23H23N3O2
2,6-Pyridinedicarboxamide, N,N'-bis(2-mercaptophenyl)- chemical structure, C19H15N3O2S2, CAS 223130-58-3
2,6-Pyridinedicarboxamide, N,N'-bis(2-mercaptophenyl)-
CAS 223130-58-3C19H15N3O2S2
n2,n6-Bis(2,6-diisopropylphenyl)pyridine-2,6-dicarboxamide chemical structure, C31H39N3O2, CAS 210155-53-6
n2,n6-Bis(2,6-diisopropylphenyl)pyridine-2,6-dicarboxamide
CAS 210155-53-6C31H39N3O2
N~2~,N~6~-Bis(2-hydroxyphenyl)pyridine-2,6-dicarboxamide chemical structure, C19H15N3O4, CAS 96308-77-9
N~2~,N~6~-Bis(2-hydroxyphenyl)pyridine-2,6-dicarboxamide
CAS 96308-77-9C19H15N3O4
N~2~,N~6~-Bis(2-aminophenyl)pyridine-2,6-dicarboxamide chemical structure, C19H17N5O2, CAS 373614-45-0
N~2~,N~6~-Bis(2-aminophenyl)pyridine-2,6-dicarboxamide
CAS 373614-45-0C19H17N5O2
4-{[(6-{[(4-Carboxyphenyl)amino]carbonyl}pyridin-2-yl)carbonyl]amino}benzoic acid chemical structure, C21H15N3O6, CAS 441314-18-7
4-{[(6-{[(4-Carboxyphenyl)amino]carbonyl}pyridin-2-yl)carbonyl]amino}benzoic acid
CAS 441314-18-7C21H15N3O6
N2,N6-diphenyl-4-(trifluoromethyl)pyridine-2,6-dicarboxamide chemical structure, C20H14F3N3O2, CAS 1092344-79-0
N2,N6-diphenyl-4-(trifluoromethyl)pyridine-2,6-dicarboxamide
CAS 1092344-79-0C20H14F3N3O2
N2,N6-bis(4-chlorophenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide chemical structure, C20H12Cl2F3N3O2, CAS 1092344-82-5
N2,N6-bis(4-chlorophenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide
CAS 1092344-82-5C20H12Cl2F3N3O2
N2,N6-bis(2-chlorophenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide chemical structure, C20H12Cl2F3N3O2, CAS 1092344-85-8
N2,N6-bis(2-chlorophenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide
CAS 1092344-85-8C20H12Cl2F3N3O2
N2,N6-bis(3-methoxyphenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide chemical structure, C22H18F3N3O4, CAS 1092344-88-1
N2,N6-bis(3-methoxyphenyl)-4-(trifluoromethyl)pyridine-2,6-dicarboxamide
CAS 1092344-88-1C22H18F3N3O4
4-(Trifluoromethyl)-N2,N6-bis[3-(trifluoromethyl)phenyl]pyridine-2,6-dicarboxamide chemical structure, C22H12F9N3O2, CAS 1092344-72-3
4-(Trifluoromethyl)-N2,N6-bis[3-(trifluoromethyl)phenyl]pyridine-2,6-dicarboxamide
CAS 1092344-72-3C22H12F9N3O2
2,2'-[Pyridine-2,6-diylbis(carbonylazanediyl)]dibenzoic acid chemical structure, C21H15N3O6, CAS 63458-77-5
2,2'-[Pyridine-2,6-diylbis(carbonylazanediyl)]dibenzoic acid
CAS 63458-77-5C21H15N3O6
N,N'-Diethyl-N,N'-di(para)tolyldipicolinamide chemical structure, C25H27N3O2, CAS 920282-21-9
N,N'-Diethyl-N,N'-di(para)tolyldipicolinamide
CAS 920282-21-9C25H27N3O2
N~2~,N~6~-Dimethyl-N~2~,N~6~-diphenylpyridine-2,6-dicarboxamide chemical structure, C21H19N3O2, CAS 95937-89-6
N~2~,N~6~-Dimethyl-N~2~,N~6~-diphenylpyridine-2,6-dicarboxamide
CAS 95937-89-6C21H19N3O2
N~2~,N~6~-Bis[2-(methylsulfanyl)phenyl]pyridine-2,6-dicarboxamide chemical structure, C21H19N3O2S2, CAS 380366-85-8
N~2~,N~6~-Bis[2-(methylsulfanyl)phenyl]pyridine-2,6-dicarboxamide
CAS 380366-85-8C21H19N3O2S2
N2,N6-bis(4-aminophenyl)-2,6-Pyridinedicarboxamide chemical structure, C19H17N5O2, CAS 1372048-27-5
N2,N6-bis(4-aminophenyl)-2,6-Pyridinedicarboxamide
CAS 1372048-27-5C19H17N5O2