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Murcko scaffold

Ring system with 3 rings and 25 atoms

59 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
59
With full pages
6
Scaffold SMILES

O=C(Nc1ccccc1)c1cccc(S(=O)(=O)Nc2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1cccc(S(=O)(=O)Nc2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

N-(2,3-Dimethylphenyl)-4-methyl-3-(2-toluidinosulfonyl)benzamide chemical structure, C23H24N2O3S, CAS 791805-58-8
N-(2,3-Dimethylphenyl)-4-methyl-3-(2-toluidinosulfonyl)benzamide
CAS 791805-58-8C23H24N2O3S
3-[(2,3-Dimethylphenyl)sulfamoyl]-4-methyl-N-phenylbenzamide chemical structure, C22H22N2O3S, CAS 717896-66-7
3-[(2,3-Dimethylphenyl)sulfamoyl]-4-methyl-N-phenylbenzamide
CAS 717896-66-7C22H22N2O3S
N-(4-Ethylphenyl)-4-methyl-3-(phenylsulfamoyl)benzamide chemical structure, C22H22N2O3S, CAS 713105-85-2
N-(4-Ethylphenyl)-4-methyl-3-(phenylsulfamoyl)benzamide
CAS 713105-85-2C22H22N2O3S
4-Chloro-N-(4-methoxyphenyl)-3-(3-toluidinosulfonyl)benzamide chemical structure, C21H19ClN2O4S, CAS 791805-15-7
4-Chloro-N-(4-methoxyphenyl)-3-(3-toluidinosulfonyl)benzamide
CAS 791805-15-7C21H19ClN2O4S
4-Methoxy-3-[(4-methoxyphenyl)sulfamoyl]-N-phenylbenzamide chemical structure, C21H20N2O5S, CAS 313260-98-9
4-Methoxy-3-[(4-methoxyphenyl)sulfamoyl]-N-phenylbenzamide
CAS 313260-98-9C21H20N2O5S
4-Bromo-N-(4-bromophenyl)-3-[(2-methylphenyl)sulfamoyl]benzamide chemical structure, C20H16Br2N2O3S, CAS 312756-76-6
4-Bromo-N-(4-bromophenyl)-3-[(2-methylphenyl)sulfamoyl]benzamide
CAS 312756-76-6C20H16Br2N2O3S
N-(4-Bromophenyl)-3-[(2-methoxyphenyl)sulfamoyl]benzamide chemical structure, C20H17BrN2O4S, CAS 313550-68-4
N-(4-Bromophenyl)-3-[(2-methoxyphenyl)sulfamoyl]benzamide
CAS 313550-68-4C20H17BrN2O4S
N-(4-Bromophenyl)-2-chloro-5-[(4-chloroanilino)sulfonyl]benzamide chemical structure, C19H13BrCl2N2O3S, CAS 331653-78-2
N-(4-Bromophenyl)-2-chloro-5-[(4-chloroanilino)sulfonyl]benzamide
CAS 331653-78-2C19H13BrCl2N2O3S
3-[(4-Bromophenyl)sulfamoyl]-N-(3-nitrophenyl)benzamide chemical structure, C19H14BrN3O5S, CAS 291536-91-9
3-[(4-Bromophenyl)sulfamoyl]-N-(3-nitrophenyl)benzamide
CAS 291536-91-9C19H14BrN3O5S
N-(3-Hydroxy-phenyl)-3-(3-hydroxy-phenylsulfamoyl)-benzamide chemical structure, C19H16N2O5S, CAS 300670-24-0
N-(3-Hydroxy-phenyl)-3-(3-hydroxy-phenylsulfamoyl)-benzamide
CAS 300670-24-0C19H16N2O5S
N-(4-Bromophenyl) 3-(4-bromophenylaminosulfonyl)benzamide chemical structure, C19H14Br2N2O3S, CAS 300670-16-0
N-(4-Bromophenyl) 3-(4-bromophenylaminosulfonyl)benzamide
CAS 300670-16-0C19H14Br2N2O3S
4-({[5-(Anilinocarbonyl)-2-chlorophenyl]sulfonyl}amino)benzoic acid chemical structure, C20H15ClN2O5S, CAS 326920-82-5
4-({[5-(Anilinocarbonyl)-2-chlorophenyl]sulfonyl}amino)benzoic acid
CAS 326920-82-5C20H15ClN2O5S
4-Chloro-3-[(2-methylphenyl)sulfamoyl]-N-phenylbenzamide chemical structure, C20H17ClN2O3S, CAS 333431-41-7
4-Chloro-3-[(2-methylphenyl)sulfamoyl]-N-phenylbenzamide
CAS 333431-41-7C20H17ClN2O3S
2-{4-Bromo-3-[(4-chlorophenyl)sulfamoyl]benzamido}benzoic acid chemical structure, C20H14BrClN2O5S, CAS 307332-01-0
2-{4-Bromo-3-[(4-chlorophenyl)sulfamoyl]benzamido}benzoic acid
CAS 307332-01-0C20H14BrClN2O5S
4-Bromo-N-(4-bromophenyl)-3-[(4-chloroanilino)sulfonyl]benzamide chemical structure, C19H13Br2ClN2O3S, CAS 324061-07-6
4-Bromo-N-(4-bromophenyl)-3-[(4-chloroanilino)sulfonyl]benzamide
CAS 324061-07-6C19H13Br2ClN2O3S
4-Bromo-N-(4-bromophenyl)-3-[(4-methoxyphenyl)sulfamoyl]benzamide chemical structure, C20H16Br2N2O4S, CAS 312756-77-7
4-Bromo-N-(4-bromophenyl)-3-[(4-methoxyphenyl)sulfamoyl]benzamide
CAS 312756-77-7C20H16Br2N2O4S
4-Bromo-3-[(4-fluorophenyl)sulfamoyl]-N-(3-nitrophenyl)benzamide chemical structure, C19H13BrFN3O5S, CAS 339004-05-6
4-Bromo-3-[(4-fluorophenyl)sulfamoyl]-N-(3-nitrophenyl)benzamide
CAS 339004-05-6C19H13BrFN3O5S
2-({3-[(3-Acetylanilino)sulfonyl]benzoyl}amino)benzoic acid chemical structure, C22H18N2O6S, CAS 314043-31-7
2-({3-[(3-Acetylanilino)sulfonyl]benzoyl}amino)benzoic acid
CAS 314043-31-7C22H18N2O6S
2-[[4-Bromo-3-[(4-methylphenyl)sulfamoyl]benzoyl]amino]benzoic acid chemical structure, C21H17BrN2O5S, CAS 331653-67-9
2-[[4-Bromo-3-[(4-methylphenyl)sulfamoyl]benzoyl]amino]benzoic acid
CAS 331653-67-9C21H17BrN2O5S
Ethyl 4-[[4-chloro-3-[(2,4-dimethylphenyl)sulfamoyl]benzoyl]amino]benzoate chemical structure, C24H23ClN2O5S, CAS 5413-12-7
Ethyl 4-[[4-chloro-3-[(2,4-dimethylphenyl)sulfamoyl]benzoyl]amino]benzoate
CAS 5413-12-7C24H23ClN2O5S
4-Chloro-3-[(2,3-dimethylphenyl)sulfamoyl]-N-(4-ethylphenyl)benzamide chemical structure, C23H23ClN2O3S, CAS 825657-42-9
4-Chloro-3-[(2,3-dimethylphenyl)sulfamoyl]-N-(4-ethylphenyl)benzamide
CAS 825657-42-9C23H23ClN2O3S
4-Chloro-N-[4-(cyanomethyl)phenyl]-3-(phenylsulfamoyl)benzamide chemical structure, C21H16ClN3O3S, CAS 825658-91-1
4-Chloro-N-[4-(cyanomethyl)phenyl]-3-(phenylsulfamoyl)benzamide
CAS 825658-91-1C21H16ClN3O3S
4-Chloro-N-[4-(cyanomethyl)phenyl]-3-[(4-methylphenyl)sulfamoyl]benzamide chemical structure, C22H18ClN3O3S, CAS 717827-93-5
4-Chloro-N-[4-(cyanomethyl)phenyl]-3-[(4-methylphenyl)sulfamoyl]benzamide
CAS 717827-93-5C22H18ClN3O3S
4-Chloro-3-[(2,3-dimethylphenyl)sulfamoyl]-N-[3-(methylsulfanyl)phenyl]benzamide chemical structure, C22H21ClN2O3S2, CAS 832106-69-1
4-Chloro-3-[(2,3-dimethylphenyl)sulfamoyl]-N-[3-(methylsulfanyl)phenyl]benzamide
CAS 832106-69-1C22H21ClN2O3S2