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Murcko scaffold

Ring system with 3 rings and 24 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
12
With full pages
7
Scaffold SMILES

O=S(=O)(Nc1nccc(C=Cc2ccccc2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1nccc(C=Cc2ccccc2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-Amino-N-[4-[(E)-2-(4-chlorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H15ClN4O2S, CAS 299936-78-0
4-Amino-N-[4-[(E)-2-(4-chlorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 299936-78-0C18H15ClN4O2S
4-Amino-N-[4-[(E)-2-(2-fluorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H15FN4O2S, CAS 330828-06-3
4-Amino-N-[4-[(E)-2-(2-fluorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 330828-06-3C18H15FN4O2S
4-Amino-N-[4-[(E)-2-(4-fluorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H15FN4O2S, CAS 332861-56-0
4-Amino-N-[4-[(E)-2-(4-fluorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 332861-56-0C18H15FN4O2S
4-Amino-N-{4-[(E)-2-(3-chlorophenyl)ethenyl]pyrimidin-2-yl}benzenesulfonamide chemical structure, C18H15ClN4O2S, CAS 299935-60-7
4-Amino-N-{4-[(E)-2-(3-chlorophenyl)ethenyl]pyrimidin-2-yl}benzenesulfonamide
CAS 299935-60-7C18H15ClN4O2S
4-Amino-N-[4-[(E)-2-(2,4-dichlorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H14Cl2N4O2S, CAS 351162-23-7
4-Amino-N-[4-[(E)-2-(2,4-dichlorophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 351162-23-7C18H14Cl2N4O2S
4-Amino-N-[4-[(E)-2-(3-bromophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H15BrN4O2S, CAS 354538-04-8
4-Amino-N-[4-[(E)-2-(3-bromophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 354538-04-8C18H15BrN4O2S
4-Amino-N-[4-[(E)-2-(4-nitrophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide chemical structure, C18H15N5O4S, CAS 351163-20-7
4-Amino-N-[4-[(E)-2-(4-nitrophenyl)ethenyl]pyrimidin-2-yl]benzenesulfonamide
CAS 351163-20-7C18H15N5O4S
N-[4-[[4-[(E)-2-(2-Chlorophenyl)ethenyl]pyrimidin-2-yl]sulfamoyl]phenyl]propanamide chemical structure, C21H19ClN4O3S, CAS 374914-06-4
N-[4-[[4-[(E)-2-(2-Chlorophenyl)ethenyl]pyrimidin-2-yl]sulfamoyl]phenyl]propanamide
CAS 374914-06-4C21H19ClN4O3S
N-[4-({4-[(E)-2-(4-chlorophenyl)ethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]acetamide chemical structure, C20H17ClN4O3S, CAS 1164475-52-8
N-[4-({4-[(E)-2-(4-chlorophenyl)ethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]acetamide
CAS 1164475-52-8C20H17ClN4O3S
N-[4-({4-[(E)-2-(2-fluorophenyl)ethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]-2-methylpropanamide chemical structure, C22H21FN4O3S, CAS 523991-60-8
N-[4-({4-[(E)-2-(2-fluorophenyl)ethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]-2-methylpropanamide
CAS 523991-60-8C22H21FN4O3S
N-{4-[({4-[2-(3,4-Dimethoxyphenyl)vinyl]-2-pyrimidinyl}amino)sulfonyl]phenyl}hexanamide chemical structure, C26H30N4O5S, CAS 523991-57-3
N-{4-[({4-[2-(3,4-Dimethoxyphenyl)vinyl]-2-pyrimidinyl}amino)sulfonyl]phenyl}hexanamide
CAS 523991-57-3C26H30N4O5S
2-Methyl-N-[4-({4-[(E)-2-phenylethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]propanamide chemical structure, C22H22N4O3S, CAS 1164548-15-5
2-Methyl-N-[4-({4-[(E)-2-phenylethenyl]pyrimidin-2-yl}sulfamoyl)phenyl]propanamide
CAS 1164548-15-5C22H22N4O3S