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Murcko scaffold

Ring system with 3 rings and 25 atoms

18 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 25
Chemicals: 18
With full pages: 8

Scaffold SMILES

O=C(Nc1cccc(S(=O)(=O)Nc2ccccc2)c1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1cccc(S(=O)(=O)Nc2ccccc2)c1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

6-Chloro-N-{3-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C19H16ClN3O4S, CAS 745068-51-3

6-Chloro-N-{3-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 745068-51-3C₁₉H₁₆ClN₃O₄S

N-[5-[(3-Bromo-4-methoxyphenyl)sulfamoyl]-2-chlorophenyl]-2-chloropyridine-3-carboxamide chemical structure, C19H14BrCl2N3O4S, CAS 721891-31-2

N-[5-[(3-Bromo-4-methoxyphenyl)sulfamoyl]-2-chlorophenyl]-2-chloropyridine-3-carboxamide

CAS 721891-31-2C₁₉H₁₄BrCl₂N₃O₄S

5-Bromo-N-[4-methoxy-3-[(4-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide chemical structure, C20H18BrN3O5S, CAS 571160-95-7

5-Bromo-N-[4-methoxy-3-[(4-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide

CAS 571160-95-7C₂₀H₁₈BrN₃O₅S

2-Chloro-N-{2-chloro-5-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C19H15Cl2N3O4S, CAS 748146-99-8

2-Chloro-N-{2-chloro-5-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 748146-99-8C₁₉H₁₅Cl₂N₃O₄S

6-Chloro-N-{4-methoxy-3-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C20H18ClN3O5S, CAS 783315-09-3

6-Chloro-N-{4-methoxy-3-[(4-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 783315-09-3C₂₀H₁₈ClN₃O₅S

6-Chloro-N-(3-{[3-(trifluoromethyl)phenyl]sulfamoyl}phenyl)pyridine-3-carboxamide chemical structure, C19H13ClF3N3O3S, CAS 786716-58-3

6-Chloro-N-(3-{[3-(trifluoromethyl)phenyl]sulfamoyl}phenyl)pyridine-3-carboxamide

CAS 786716-58-3C₁₉H₁₃ClF₃N₃O₃S

N-{3-[(3-Bromo-4-ethoxyphenyl)sulfamoyl]-4-methoxyphenyl}-2-chloropyridine-3-carboxamide chemical structure, C21H19BrClN3O5S, CAS 721890-86-4

N-{3-[(3-Bromo-4-ethoxyphenyl)sulfamoyl]-4-methoxyphenyl}-2-chloropyridine-3-carboxamide

CAS 721890-86-4C₂₁H₁₉BrClN₃O₅S

5-Bromo-N-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide chemical structure, C19H16BrN3O4S, CAS 786721-51-5

5-Bromo-N-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide

CAS 786721-51-5C₁₉H₁₆BrN₃O₄S

N-{3-[Methyl(phenyl)sulfamoyl]phenyl}-2-(methylsulfanyl)pyridine-3-carboxamide chemical structure, C20H19N3O3S2, CAS 756845-42-8

N-{3-[Methyl(phenyl)sulfamoyl]phenyl}-2-(methylsulfanyl)pyridine-3-carboxamide

CAS 756845-42-8C₂₀H₁₉N₃O₃S₂

6-Chloro-N-[4-(diethylamino)-3-[(2-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide chemical structure, C23H25ClN4O4S, CAS 757213-47-1

6-Chloro-N-[4-(diethylamino)-3-[(2-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide

CAS 757213-47-1C₂₃H₂₅ClN₄O₄S

2-Chloro-N-[5-[(2,5-dichlorophenyl)sulfamoyl]-2-(diethylamino)phenyl]pyridine-3-carboxamide chemical structure, C22H21Cl3N4O3S, CAS 729560-90-1

2-Chloro-N-[5-[(2,5-dichlorophenyl)sulfamoyl]-2-(diethylamino)phenyl]pyridine-3-carboxamide

CAS 729560-90-1C₂₂H₂₁Cl₃N₄O₃S

5,6-Dichloro-N-{3-[(2-chlorophenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C18H12Cl3N3O3S, CAS 782453-73-0

5,6-Dichloro-N-{3-[(2-chlorophenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 782453-73-0C₁₈H₁₂Cl₃N₃O₃S

6-Chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide chemical structure, C18H13Cl2N3O3S, CAS 790706-49-9

6-Chloro-N-[3-[(2-chlorophenyl)sulfamoyl]phenyl]-3-pyridinecarboxamide

CAS 790706-49-9C₁₈H₁₃Cl₂N₃O₃S

2-Chloro-N-[4-(diethylamino)-3-[(4-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide chemical structure, C23H25ClN4O4S, CAS 851103-49-6

2-Chloro-N-[4-(diethylamino)-3-[(4-methoxyphenyl)sulfamoyl]phenyl]pyridine-3-carboxamide

CAS 851103-49-6C₂₃H₂₅ClN₄O₄S

6-Chloro-N-{4-chloro-3-[(2-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C19H15Cl2N3O4S, CAS 731816-13-0

6-Chloro-N-{4-chloro-3-[(2-methoxyphenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 731816-13-0C₁₉H₁₅Cl₂N₃O₄S

6-Chloro-N-{3-[(4-chlorophenyl)sulfamoyl]phenyl}pyridine-3-carboxamide chemical structure, C18H13Cl2N3O3S, CAS 326870-94-4

6-Chloro-N-{3-[(4-chlorophenyl)sulfamoyl]phenyl}pyridine-3-carboxamide

CAS 326870-94-4C₁₈H₁₃Cl₂N₃O₃S

5,6-Dichloro-N-[5-[ethyl(phenyl)sulfamoyl]-2-methoxyphenyl]pyridine-3-carboxamide chemical structure, C21H19Cl2N3O4S, CAS 872194-40-6

5,6-Dichloro-N-[5-[ethyl(phenyl)sulfamoyl]-2-methoxyphenyl]pyridine-3-carboxamide

CAS 872194-40-6C₂₁H₁₉Cl₂N₃O₄S

N-{3-[(4-Bromophenyl)sulfamoyl]phenyl}-6-chloropyridine-3-carboxamide chemical structure, C18H13BrClN3O3S, CAS 1012922-02-9

N-{3-[(4-Bromophenyl)sulfamoyl]phenyl}-6-chloropyridine-3-carboxamide

CAS 1012922-02-9C₁₈H₁₃BrClN₃O₃S