Murcko scaffold
Ring system with 1 ring and 7 atoms
87 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 87
- With full pages
- 10
Scaffold SMILES
N=C1C=CCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 87 chemicals
2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, oxime
C10H15NO
(NE)-N-(3,5,5-trimethyl-1-cyclohex-2-enylidene)hydroxylamine
C9H15NO
(1Z)-3,5,5-Trimethyl-N-(prop-2-en-1-yl)cyclohex-2-en-1-imine
CAS 6302-40-5C12H19N
N-(3-Ethoxycyclohex-2-en-1-ylidene)hydroxylamine
C8H13NO2
Cyclohexenone oxime
CAS 3349-62-0C6H9NO
3,5-Dimethyl-2-cyclohexen-1-one O-methyl oxime
C9H15NO
(Cyclohex-2-en-1-ylideneamino)urea
CAS 5672-56-0C7H11N3O
(+)-2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-one O-methyl oxime
C11H17NO
3-Methyl-2-cyclohexen-1-one O-methyl oxime
CAS 56336-07-3C8H13NO
2-Cyclohexen-1-one, 3,5-dimethyl-, oxime
CAS 67543-92-4C8H13NO
![[(3,5,5-Trimethylcyclohex-2-en-1-ylidene)amino]urea chemical structure, C10H17N3O, CAS 914910-49-9](/s/POWGERBYLYXZDD-XYOKQWHBSA-N.svg)
[(3,5,5-Trimethylcyclohex-2-en-1-ylidene)amino]urea
CAS 914910-49-9C10H17N3O
(1Z)-3,5,5-Trimethyl-2-cyclohexen-1-one oxime
C9H15NO
Isophorone semicarbazone
CAS 6293-60-3C10H17N3O
Carvone oxime
CAS 31198-76-2C10H15NO
![[(Z)-(2-Methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ylidene)amino]urea chemical structure, C11H17N3O, CAS 4581-65-1](/s/ROYUYJQRQPJMFE-RAXLEYEMSA-N.svg)
[(Z)-(2-Methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ylidene)amino]urea
CAS 4581-65-1C11H17N3O
![[(E)-(3-Methyl-6-propan-2-ylcyclohex-2-en-1-ylidene)amino]urea chemical structure, C11H19N3O, CAS 4713-41-1](/s/MMHNCDFKONMERY-RAXLEYEMSA-N.svg)
[(E)-(3-Methyl-6-propan-2-ylcyclohex-2-en-1-ylidene)amino]urea
CAS 4713-41-1C11H19N3O
(1E)-2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-one oxime
CAS 55658-55-4C10H15NO
2-Cyclohexen-1-one, 3-ethoxy-, oxime
C8H13NO2
(NZ)-N-(3-ethoxycyclohex-2-en-1-ylidene)hydroxylamine
CAS 7467-13-2C8H13NO2
![[(Z)-(3-Ethoxycyclohex-2-en-1-ylidene)amino]urea chemical structure, C9H15N3O2, CAS 6331-79-9](/s/DXUMHQSDKXSVPC-XFFZJAGNSA-N.svg)
[(Z)-(3-Ethoxycyclohex-2-en-1-ylidene)amino]urea
CAS 6331-79-9C9H15N3O2
![[(Z)-(3-Methylcyclohex-2-en-1-ylidene)amino]thiourea chemical structure, C8H13N3S, CAS 861316-71-4](/s/YSFRPMZEKVIQMF-YFHOEESVSA-N.svg)
[(Z)-(3-Methylcyclohex-2-en-1-ylidene)amino]thiourea
CAS 861316-71-4C8H13N3S
![3-[(6Z)-6-Hydroxyimino-2-methylcyclohexen-1-yl]propan-1-ol chemical structure, C10H17NO2, CAS 6684-62-4](/s/KCCBMYQKTUIAFW-KHPPLWFESA-N.svg)
3-[(6Z)-6-Hydroxyimino-2-methylcyclohexen-1-yl]propan-1-ol
CAS 6684-62-4C10H17NO2
![[(Z)-(3-Methylcyclohex-2-en-1-ylidene)amino]urea chemical structure, C8H13N3O, CAS 56967-87-4](/s/XCZHWHPKBJQSGU-YFHOEESVSA-N.svg)
[(Z)-(3-Methylcyclohex-2-en-1-ylidene)amino]urea
CAS 56967-87-4C8H13N3O
(Z)-Methyl 4-(acetoxyimino)-2-methyl-6-pentylcyclohex-2-enecarboxylate
CAS 326026-40-8C16H25NO4
- (Z)-Methyl 4-(hydroxyimino)-2-methyl-6-pentylcyclohex-2-enecarboxylate326026-49-7C14H23NO3
- (NE)-N-(3,5,5-trimethylcyclohex-2-en-1-ylidene)hydroxylamine2157-58-6C9H15NO
- [(E)-(3,5-Dimethylcyclohex-2-en-1-ylidene)amino]urea60221-05-8C9H15N3O
- 2-Cyclohexen-1-one, 6-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)-3,5,5-trimethyl-, hydrazone101564-51-6C12H16F6N2O
- N-[2-[(5Z)-5-Hydroxyimino-4-methylcyclohex-3-en-1-yl]propan-2-yl]acetamide646034-66-4C12H20N2O2
- N-[(1E,5S)-2-Methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ylidene]hydroxylamine2051-55-0C10H15NO
- (NZ)-N-[(5S)-2-methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ylidene]hydroxylamineC10H15NO
- [(E)-(5-Methyl-2-propan-2-ylcyclohex-2-en-1-ylidene)amino]urea5113-67-7C11H19N3O
- 2-Cyclohexen-1-one, 6-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)-3,5,5-trimethyl-, thiosemicarbazone101931-82-2C13H17F6N3OS
- 2-Cyclohexen-1-one, 6-(1,1,1,3,3,3-hexafluoro-2-hydroxy-2-propyl)-3,5,5-trimethyl-, semicarbazone101931-81-1C13H17F6N3O2
- 2-Cyclohexen-1-one, oxime, (Z)-2229-00-7C6H9NO
- 2-Cyclohexen-1-one, 3,5-dimethyl-, O-methyloxime56336-06-2C9H15NO
- 2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, O-methyloxime, (+)-57397-12-3C11H17NO
- (E)2,3-Dimethylcyclohex-2-en,oxime433211-45-1C8H13NO
- 3-Amino-2-cyclohexene-1-imine145191-63-5C6H10N2
- 1-Cyclohexene-1-carbonitrile, 2-amino-3,3,4,4,5,5-hexafluoro-6-imino-90408-50-7C7H3F6N3
- (1E)-3-Methoxy-N-methylcyclohex-2-en-1-imine87883-63-4C8H13NO
- Palythine67731-19-5C10H16N2O5
- 3-Ethoxy-5,5-dimethylcyclohex-2-en-1-iminium iodide957487-03-5C10H18INO
- (NE)-N-(6-methyl-3-propan-2-ylcyclohex-2-en-1-ylidene)hydroxylamine74947-08-3C10H17NO
- N-(2-Methylcyclohex-2-en-1-ylidene)hydroxylamine19150-87-9C7H11NO
- 3-Imino-5,5-dimethyl-1-cyclohexen-1-amine23008-45-9C8H14N2
- (1Z)-N,5,5-Trimethyl-3-(methylsulfanyl)cyclohex-2-en-1-imine89390-53-4C10H17NS
- 3-(Methylsulfanyl)cyclohex-2-en-1-imine106055-10-1C7H11NS
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1cccc[nH]1](/scaffold/UBQKCCHYAOITMY-UHFFFAOYSA-N/structure.svg)
