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Murcko scaffold

Ring system with 3 rings and 17 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
33
With full pages
10
Scaffold SMILES

S=c1[nH]nc(-c2cc[nH]n2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2cc[nH]n2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

5-(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H14ClN5S, CAS 512808-30-9
5-(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512808-30-9C14H14ClN5S
5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H15N5S, CAS 512808-78-5
5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512808-78-5C14H15N5S
5-(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H16ClN5OS, CAS 512809-02-8
5-(4-Chloro-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512809-02-8C15H16ClN5OS
5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H17N5OS, CAS 512809-12-0
5-(1,5-Dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512809-12-0C15H17N5OS
5-(4-Chloro-1-methyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H12ClN5S, CAS 512810-84-3
5-(4-Chloro-1-methyl-1H-pyrazol-3-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512810-84-3C13H12ClN5S
3-(4-Chloro-1-methylpyrazol-3-yl)-4-phenyl-1H-1,2,4-triazole-5-thione chemical structure, C12H10ClN5S, CAS 512811-03-9
3-(4-Chloro-1-methylpyrazol-3-yl)-4-phenyl-1H-1,2,4-triazole-5-thione
CAS 512811-03-9C12H10ClN5S
5-(4-Chloro-1-methyl-1H-pyrazol-3-yl)-4-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H12ClN5OS, CAS 494790-63-5
5-(4-Chloro-1-methyl-1H-pyrazol-3-yl)-4-(2-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 494790-63-5C13H12ClN5OS
3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C14H14ClN5S, CAS 957299-02-4
3-(4-Chloro-2,5-dimethylpyrazol-3-yl)-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione
CAS 957299-02-4C14H14ClN5S
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H17N5OS, CAS 512808-52-5
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512808-52-5C15H17N5OS
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H12FN5S, CAS 512808-38-7
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS 512808-38-7C13H12FN5S
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H15N5S, CAS 512808-46-7
5-(1,3-Dimethyl-1H-pyrazol-5-yl)-4-(4-methylphenyl)-4H-1,2,4-triazole-3-thiol
CAS 512808-46-7C14H15N5S
5-(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H11ClFN5S, CAS 512810-77-4
5-(4-Chloro-1,3-dimethyl-1H-pyrazol-5-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS 512810-77-4C13H11ClFN5S
5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H11BrFN5S, CAS 512812-05-4
5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-fluorophenyl)-4H-1,2,4-triazole-3-thiol
CAS 512812-05-4C13H11BrFN5S
5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H16BrN5OS, CAS 494790-36-2
5-(4-Bromo-1,5-dimethyl-1H-pyrazol-3-yl)-4-(4-ethoxyphenyl)-4H-1,2,4-triazole-3-thiol
CAS 494790-36-2C15H16BrN5OS
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C16H19N5OS, CAS 879450-80-3
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(4-methoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 879450-80-3C16H19N5OS
4-(2,5-Dimethoxyphenyl)-3-(1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H13N5O2S, CAS 879462-48-3
4-(2,5-Dimethoxyphenyl)-3-(1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione
CAS 879462-48-3C13H13N5O2S
5-(5-Methyl-1H-pyrazol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiol chemical structure, C12H11N5S, CAS 1022902-08-4
5-(5-Methyl-1H-pyrazol-3-yl)-4-phenyl-4H-1,2,4-triazole-3-thiol
CAS 1022902-08-4C12H11N5S
2-[4-[3-(4-Bromo-2,5-dimethylpyrazol-3-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]acetic acid chemical structure, C15H14BrN5O2S, CAS 879469-34-8
2-[4-[3-(4-Bromo-2,5-dimethylpyrazol-3-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]acetic acid
CAS 879469-34-8C15H14BrN5O2S
4-(2-Chlorophenyl)-3-(1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione chemical structure, C11H8ClN5S, CAS 1035974-30-1
4-(2-Chlorophenyl)-3-(1H-pyrazol-5-yl)-1H-1,2,4-triazole-5-thione
CAS 1035974-30-1C11H8ClN5S
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(4-chlorophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H16ClN5S, CAS 879567-71-2
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(4-chlorophenyl)-1H-1,2,4-triazole-5-thione
CAS 879567-71-2C15H16ClN5S
4-[3-(4-Chloro-1-ethylpyrazol-3-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]benzenesulfonamide chemical structure, C13H13ClN6O2S2, CAS 879448-40-5
4-[3-(4-Chloro-1-ethylpyrazol-3-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]benzenesulfonamide
CAS 879448-40-5C13H13ClN6O2S2
3-(4-Chloro-1-ethylpyrazol-3-yl)-4-(2,5-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H16ClN5O2S, CAS 879449-11-3
3-(4-Chloro-1-ethylpyrazol-3-yl)-4-(2,5-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 879449-11-3C15H16ClN5O2S
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(2-fluorophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C15H16FN5S, CAS 879429-59-1
3-(5-tert-Butyl-1H-pyrazol-3-yl)-4-(2-fluorophenyl)-1H-1,2,4-triazole-5-thione
CAS 879429-59-1C15H16FN5S
3-(2,5-Dimethylpyrazol-3-yl)-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione chemical structure, C14H15N5OS, CAS 512808-83-2
3-(2,5-Dimethylpyrazol-3-yl)-4-(2-methoxyphenyl)-1H-1,2,4-triazole-5-thione
CAS 512808-83-2C14H15N5OS