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Murcko scaffold

Ring system with 3 rings and 16 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
18
With full pages
5
Scaffold SMILES

c1ccc(-n2cccc2-c2cccs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2cccc2-c2cccs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Phenol, 2-(2-methyl-5-(2-thienyl)-1H-pyrrol-1-yl)- chemical structure, C15H13NOS, CAS 91318-39-7
Phenol, 2-(2-methyl-5-(2-thienyl)-1H-pyrrol-1-yl)-
CAS 91318-39-7C15H13NOS
3-(1-(4-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)propanoic acid chemical structure, C17H14ClNO2S, CAS 677018-60-9
3-(1-(4-Chlorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)propanoic acid
CAS 677018-60-9C17H14ClNO2S
3-[1-(3-Chloro-4-methylphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C18H16ClNO2S, CAS 432508-97-9
3-[1-(3-Chloro-4-methylphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid
CAS 432508-97-9C18H16ClNO2S
3-(1-(5-Chloro-2-methylphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)propanoic acid chemical structure, C18H16ClNO2S, CAS 683809-22-5
3-(1-(5-Chloro-2-methylphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl)propanoic acid
CAS 683809-22-5C18H16ClNO2S
3-[1-(2-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C17H14FNO2S, CAS 443667-02-5
3-[1-(2-Fluorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid
CAS 443667-02-5C17H14FNO2S
3-[1-(4-Hydroxyphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C17H15NO3S, CAS 432522-99-1
3-[1-(4-Hydroxyphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid
CAS 432522-99-1C17H15NO3S
3-{1-[4-(Dimethylamino)phenyl]-5-(thiophen-2-yl)-1H-pyrrol-2-yl}propanoic acid chemical structure, C19H20N2O2S, CAS 693798-21-9
3-{1-[4-(Dimethylamino)phenyl]-5-(thiophen-2-yl)-1H-pyrrol-2-yl}propanoic acid
CAS 693798-21-9C19H20N2O2S
3-[1-(4-Acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acid chemical structure, C19H17NO3S, CAS 693808-15-0
3-[1-(4-Acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acid
CAS 693808-15-0C19H17NO3S
3-[1-(3-Acetylphenyl)-5-(2-thienyl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C19H17NO3S, CAS 693813-04-6
3-[1-(3-Acetylphenyl)-5-(2-thienyl)-1H-pyrrol-2-yl]propanoic acid
CAS 693813-04-6C19H17NO3S
4-[2-(2-Carboxyethyl)-5-thiophen-2-ylpyrrol-1-yl]benzoic acid chemical structure, C18H15NO4S, CAS 693821-70-4
4-[2-(2-Carboxyethyl)-5-thiophen-2-ylpyrrol-1-yl]benzoic acid
CAS 693821-70-4C18H15NO4S
3-[1-(4-Bromophenyl)-5-(2-thienyl)pyrrol-2-yl]propanoic acid chemical structure, C17H14BrNO2S, CAS 676639-23-9
3-[1-(4-Bromophenyl)-5-(2-thienyl)pyrrol-2-yl]propanoic acid
CAS 676639-23-9C17H14BrNO2S
3-(5-(Thiophen-2-yl)-1-(2-(trifluoromethyl)phenyl)-1H-pyrrol-2-yl)propanoic acid chemical structure, C18H14F3NO2S, CAS 432533-60-3
3-(5-(Thiophen-2-yl)-1-(2-(trifluoromethyl)phenyl)-1H-pyrrol-2-yl)propanoic acid
CAS 432533-60-3C18H14F3NO2S
3-{1-[4-(Ethoxycarbonyl)phenyl]-5-(thiophen-2-yl)-1H-pyrrol-2-yl}propanoic acid chemical structure, C20H19NO4S, CAS 682759-81-5
3-{1-[4-(Ethoxycarbonyl)phenyl]-5-(thiophen-2-yl)-1H-pyrrol-2-yl}propanoic acid
CAS 682759-81-5C20H19NO4S
3-[1-(2,5-Dichlorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C17H13Cl2NO2S, CAS 682348-22-7
3-[1-(2,5-Dichlorophenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid
CAS 682348-22-7C17H13Cl2NO2S
3-[1-(3,4-Dichlorophenyl)-5-(2-thienyl)pyrrol-2-yl]propanoic acid chemical structure, C17H13Cl2NO2S, CAS 682348-23-8
3-[1-(3,4-Dichlorophenyl)-5-(2-thienyl)pyrrol-2-yl]propanoic acid
CAS 682348-23-8C17H13Cl2NO2S
3-[1-(5-Chloro-2-methoxyphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid chemical structure, C18H16ClNO3S, CAS 678189-28-1
3-[1-(5-Chloro-2-methoxyphenyl)-5-(thiophen-2-yl)-1H-pyrrol-2-yl]propanoic acid
CAS 678189-28-1C18H16ClNO3S
1H-Pyrrole, 1-(4-chlorophenyl)-2-methyl-5-(2-thienyl)- chemical structure, C15H12ClNS, CAS 91307-06-1
1H-Pyrrole, 1-(4-chlorophenyl)-2-methyl-5-(2-thienyl)-
CAS 91307-06-1C15H12ClNS
1H-Pyrrole, 1-(2,4-dimethoxyphenyl)-2-(2-thienyl)- chemical structure, C16H15NO2S, CAS 849403-53-8
1H-Pyrrole, 1-(2,4-dimethoxyphenyl)-2-(2-thienyl)-
CAS 849403-53-8C16H15NO2S