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Murcko scaffold

1-Phenyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one scaffold

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
33
With full pages
6
Scaffold SMILES

O=c1ccn(-c2ccccc2)c(=S)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one page
Murcko scaffold O=c1ccn(-c2ccccc2)c(=S)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

6-Amino-1-(4-methylphenyl)-2-sulfanylidenepyrimidin-4-one chemical structure, C11H11N3OS, CAS 180028-90-4
6-Amino-1-(4-methylphenyl)-2-sulfanylidenepyrimidin-4-one
CAS 180028-90-4C11H11N3OS
6-Amino-1-(2-chlorophenyl)-2,3-dihydro-2-thioxopyrimidine-4-one chemical structure, C10H8ClN3OS, CAS 180028-92-6
6-Amino-1-(2-chlorophenyl)-2,3-dihydro-2-thioxopyrimidine-4-one
CAS 180028-92-6C10H8ClN3OS
6-Amino-1-(4-chlorophenyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone chemical structure, C10H8ClN3OS, CAS 16837-11-9
6-Amino-1-(4-chlorophenyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
CAS 16837-11-9C10H8ClN3OS
6-Amino-1-(4-methylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde chemical structure, C12H11N3O2S, CAS 887580-91-8
6-Amino-1-(4-methylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
CAS 887580-91-8C12H11N3O2S
6-Amino-1-(4-methoxyphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde chemical structure, C12H11N3O3S, CAS 887581-21-7
6-Amino-1-(4-methoxyphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
CAS 887581-21-7C12H11N3O3S
6-Amino-2-thioxo-1-(m-tolyl)-2,3-dihydropyrimidin-4(1H)-one chemical structure, C11H11N3OS, CAS 347319-41-9
6-Amino-2-thioxo-1-(m-tolyl)-2,3-dihydropyrimidin-4(1H)-one
CAS 347319-41-9C11H11N3OS
6-Amino-1-(4-fluorophenyl)-2-sulfanylidenepyrimidin-4-one chemical structure, C10H8FN3OS, CAS 713507-36-9
6-Amino-1-(4-fluorophenyl)-2-sulfanylidenepyrimidin-4-one
CAS 713507-36-9C10H8FN3OS
6-Amino-1-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C10H9N3OS, CAS 15837-46-4
6-Amino-1-phenyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 15837-46-4C10H9N3OS
6-Hydroxy-3-(3-methoxyphenyl)-2-sulfanyl-3,4-dihydropyrimidin-4-one chemical structure, C11H10N2O3S, CAS 1147192-75-3
6-Hydroxy-3-(3-methoxyphenyl)-2-sulfanyl-3,4-dihydropyrimidin-4-one
CAS 1147192-75-3C11H10N2O3S
6-Amino-2-thioxo-1-(3-(trifluoromethyl)phenyl)-2,3-dihydropyrimidin-4(1H)-one chemical structure, C11H8F3N3OS, CAS 717827-97-9
6-Amino-2-thioxo-1-(3-(trifluoromethyl)phenyl)-2,3-dihydropyrimidin-4(1H)-one
CAS 717827-97-9C11H8F3N3OS
6-Amino-1-(2-methylphenyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone chemical structure, C11H11N3OS, CAS 180028-91-5
6-Amino-1-(2-methylphenyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
CAS 180028-91-5C11H11N3OS
(5E)-5-({[2-(Dimethylamino)ethyl]amino}methylidene)-1-(3-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione chemical structure, C16H20N4O3S, CAS 378757-16-5
(5E)-5-({[2-(Dimethylamino)ethyl]amino}methylidene)-1-(3-methoxyphenyl)-2-sulfanylpyrimidine-4,6(1H,5H)-dione
CAS 378757-16-5C16H20N4O3S
5-({[2-(Diethylamino)ethyl]amino}methylene)-1-(4-methylphenyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione chemical structure, C18H24N4O2S, CAS 352350-12-0
5-({[2-(Diethylamino)ethyl]amino}methylene)-1-(4-methylphenyl)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
CAS 352350-12-0C18H24N4O2S
1-Phenyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one chemical structure, C10H8N2OS, CAS 21320-99-0
1-Phenyl-2-sulfanylidene-2,3-dihydropyrimidin-4(1H)-one
CAS 21320-99-0C10H8N2OS
5-Ethyl-6-hydroxy-3-(2-methylphenyl)-2-sulfanyl-3,4-dihydropyrimidin-4-one chemical structure, C13H14N2O2S, CAS 1189867-74-0
5-Ethyl-6-hydroxy-3-(2-methylphenyl)-2-sulfanyl-3,4-dihydropyrimidin-4-one
CAS 1189867-74-0C13H14N2O2S
6-Amino-1-(4-bromophenyl)-2-sulfanylidenepyrimidin-4-one chemical structure, C10H8BrN3OS, CAS 16837-12-0
6-Amino-1-(4-bromophenyl)-2-sulfanylidenepyrimidin-4-one
CAS 16837-12-0C10H8BrN3OS
6-Amino-1-(4-iodophenyl)-2-sulfanylidenepyrimidin-4-one chemical structure, C10H8IN3OS, CAS 16837-13-1
6-Amino-1-(4-iodophenyl)-2-sulfanylidenepyrimidin-4-one
CAS 16837-13-1C10H8IN3OS
6-Amino-1-(4-methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C11H11N3O2S, CAS 180028-93-7
6-Amino-1-(4-methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 180028-93-7C11H11N3O2S
6-Amino-1-(3-methoxyphenyl)-2-sulfanylidenepyrimidin-4-one chemical structure, C11H11N3O2S, CAS 887202-03-1
6-Amino-1-(3-methoxyphenyl)-2-sulfanylidenepyrimidin-4-one
CAS 887202-03-1C11H11N3O2S
6-Amino-1-(2-methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C11H11N3O2S, CAS 180028-94-8
6-Amino-1-(2-methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 180028-94-8C11H11N3O2S
6-Amino-1-(3,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one chemical structure, C12H13N3OS, CAS 887202-10-0
6-Amino-1-(3,4-dimethylphenyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
CAS 887202-10-0C12H13N3OS
6-Amino-1-(2-methylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde chemical structure, C12H11N3O2S, CAS 887580-98-5
6-Amino-1-(2-methylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbaldehyde
CAS 887580-98-5C12H11N3O2S
1-(2,4-Dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C10H6Cl2N2O2S, CAS 340216-38-8
1-(2,4-Dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 340216-38-8C10H6Cl2N2O2S
1-(3,4-Dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one chemical structure, C10H6Cl2N2O2S, CAS 340216-43-5
1-(3,4-Dichlorophenyl)-6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
CAS 340216-43-5C10H6Cl2N2O2S