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Murcko scaffold

Ring system with 5 rings and 28 atoms

20 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
20
With full pages
1
Scaffold SMILES

c1cc2cc(c1)Sc1cccc(c1)Sc1cccc(c1)Sc1cccc(c1)S2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2cc(c1)Sc1cccc(c1)Sc1cccc(c1)Sc1cccc(c1)S2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

4-tert-Butylthiacalix(4)arene chemical structure, C40H48O4S4, CAS 182496-55-5
4-tert-Butylthiacalix(4)arene
CAS 182496-55-5C40H48O4S4
12,32,52,72-Tetramethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane chemical structure, C28H24O4S4, CAS 219797-71-4
12,32,52,72-Tetramethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane
CAS 219797-71-4C28H24O4S4
15,35,55,75-Tetra-tert-butyl-12,32,52,72-tetramethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane chemical structure, C44H56O4S4, CAS 182496-68-0
15,35,55,75-Tetra-tert-butyl-12,32,52,72-tetramethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane
CAS 182496-68-0C44H56O4S4
Agn-PC-0LP4U9 chemical structure, C56H72O12S4, CAS 210706-03-9
Agn-PC-0LP4U9
CAS 210706-03-9C56H72O12S4
Thiacalix(4)arene chemical structure, C24H16O4S4, CAS 182496-69-1
Thiacalix(4)arene
CAS 182496-69-1C24H16O4S4
Sulfonato-thiacalix[4]arene chemical structure, C24H16O16S8, CAS 237770-97-7
Sulfonato-thiacalix[4]arene
CAS 237770-97-7C24H16O16S8
Agn-PC-0ncnfs chemical structure, C24H12Na4O16S8, CAS 211561-04-5
Agn-PC-0ncnfs
CAS 211561-04-5C24H12Na4O16S8
15,35,55,75-Tetrakis(2,4,4-trimethylpentan-2-yl)-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol chemical structure, C56H80O4S4, CAS 182496-64-6
15,35,55,75-Tetrakis(2,4,4-trimethylpentan-2-yl)-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol
CAS 182496-64-6C56H80O4S4
15,35,55,75-Tetrakis(chloromethyl)-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol chemical structure, C28H20Cl4O4S4, CAS 244087-92-1
15,35,55,75-Tetrakis(chloromethyl)-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol
CAS 244087-92-1C28H20Cl4O4S4
15,35,55,75-Tetra-tert-butyl-32,72-dimethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diol chemical structure, C42H52O4S4, CAS 500316-93-8
15,35,55,75-Tetra-tert-butyl-32,72-dimethoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diol
CAS 500316-93-8C42H52O4S4
2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dihydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetic acid chemical structure, C44H52O8S4, CAS 209472-17-3
2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dihydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetic acid
CAS 209472-17-3C44H52O8S4
12,32,52,72-Tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrasulfonate,stereoisomer chemical structure, C24H12O16S8-4, CAS 499991-98-9
12,32,52,72-Tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrasulfonate,stereoisomer
CAS 499991-98-9C24H12O16S8-4
15,35,55,75-Tetrabromo-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol chemical structure, C24H12Br4O4S4, CAS 182496-70-4
15,35,55,75-Tetrabromo-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetraol
CAS 182496-70-4C24H12Br4O4S4
2,2',2'',2'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetraacetic acid chemical structure, C48H56O12S4, CAS 749252-53-7
2,2',2'',2'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetraacetic acid
CAS 749252-53-7C48H56O12S4
Diethyl 2,2'-((15,35,55,75-tetra-tert-butyl-32,72-dihydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetate chemical structure, C48H60O8S4, CAS 252253-24-0
Diethyl 2,2'-((15,35,55,75-tetra-tert-butyl-32,72-dihydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetate
CAS 252253-24-0C48H60O8S4
((12,32,52,72-Tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrayl)tetrakis(methylene))tetrakis(phosphonic acid) chemical structure, C28H28O16P4S4, CAS 1208334-97-7
((12,32,52,72-Tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrayl)tetrakis(methylene))tetrakis(phosphonic acid)
CAS 1208334-97-7C28H28O16P4S4
2,2',2'',2'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetra(acetohydrazide) chemical structure, C48H64N8O8S4, CAS 942601-55-0
2,2',2'',2'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetra(acetohydrazide)
CAS 942601-55-0C48H64N8O8S4
Octaethyl ((12,32,52,72-tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrayl)tetrakis(methylene))tetrakis(phosphonate) chemical structure, C44H60O16P4S4, CAS 610253-93-5
Octaethyl ((12,32,52,72-tetrahydroxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-15,35,55,75-tetrayl)tetrakis(methylene))tetrakis(phosphonate)
CAS 610253-93-5C44H60O16P4S4
2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dipropoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))bis(ethan-1-amine),stereoisomer chemical structure, C50H70N2O4S4, CAS 931407-18-0
2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dipropoxy-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))bis(ethan-1-amine),stereoisomer
CAS 931407-18-0C50H70N2O4S4
3,3',3'',3'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetrakis(propan-1-amine),stereoisomer chemical structure, C52H76N4O4S4, CAS 1423621-83-3
3,3',3'',3'''-((15,35,55,75-Tetra-tert-butyl-2,4,6,8-tetrathia-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetrakis(propan-1-amine),stereoisomer
CAS 1423621-83-3C52H76N4O4S4