Murcko scaffold
Calix(4)arene scaffold
91 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 91
- With full pages
- 9
Scaffold SMILES
c1cc2cc(c1)Cc1cccc(c1)Cc1cccc(c1)Cc1cccc(c1)C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 91 chemicals
![4-tert-Butylcalix[4]arene chemical structure, C44H56O4, CAS 60705-62-6](/s/NVKLTRSBZLYZHK-UHFFFAOYSA-N.svg)
4-tert-Butylcalix[4]arene
CAS 60705-62-6C44H56O4
![P-Isopropylcalix[4]arene chemical structure, C40H48O4, CAS 97998-55-5](/s/UHLRPXXFPYMCAE-UHFFFAOYSA-N.svg)
P-Isopropylcalix[4]arene
CAS 97998-55-5C40H48O4
![5,11,17,23-Tetrakis(1,1,3,3-tetramethylbutyl)calix[4]arene-25,26,27,28-tetrol chemical structure, C60H88O4, CAS 42607-92-1](/s/KCUQVAUQRGDGKP-UHFFFAOYSA-N.svg)
5,11,17,23-Tetrakis(1,1,3,3-tetramethylbutyl)calix[4]arene-25,26,27,28-tetrol
CAS 42607-92-1C60H88O4
25,26,27,28-Tetrahydroxycalix(4)arene
CAS 74568-07-3C28H24O4
![4-Sulfonic calix[4]arene hydrate 95% chemical structure, C28H42O25S4, CAS 139553-70-1](/s/SYNGAYKUCBFIDV-UHFFFAOYSA-N.svg)
4-Sulfonic calix[4]arene hydrate 95%
CAS 139553-70-1C28H42O25S4
![25,26,27,28-Tetrahydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid chemical structure, C28H24O16S4, CAS 112269-92-8](/s/JFYBCAFLVNKHHG-UHFFFAOYSA-N.svg)
25,26,27,28-Tetrahydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid
CAS 112269-92-8C28H24O16S4
1,3-Dimethoxy-4-tert-butylcalix(4)arene
CAS 122406-45-5C46H60O4
Sodium ionophore X
CAS 97600-39-0C60H80O12
![4,6,10,12,16,18,22,24,25,26,27,28-Dodecamethylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-5,11,17,23-tetrol chemical structure, C40H48O4, CAS 145572-23-2](/s/WAKLCZAHNJRGDW-UHFFFAOYSA-N.svg)
4,6,10,12,16,18,22,24,25,26,27,28-Dodecamethylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-5,11,17,23-tetrol
CAS 145572-23-2C40H48O4
![28-Ethoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3(28),4,6,9,11,13(27),15,17,19(26),21(25),22-dodecaene-25,26,27-triol chemical structure, C30H28O4, CAS 138240-24-1](/s/SHFDWVUQUZVZKN-UHFFFAOYSA-N.svg)
28-Ethoxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3(28),4,6,9,11,13(27),15,17,19(26),21(25),22-dodecaene-25,26,27-triol
CAS 138240-24-1C30H28O4
![25,27-Dipropoxycalix[4]arene chemical structure, C34H36O4, CAS 162301-48-6](/s/JJYQEKZDWWUIQB-UHFFFAOYSA-N.svg)
25,27-Dipropoxycalix[4]arene
CAS 162301-48-6C34H36O4
![25,26,27,28-Tetrapropoxycalix[4]arene chemical structure, C40H48O4, CAS 147782-22-7](/s/YDRMWZTYFKKFIT-UHFFFAOYSA-N.svg)
25,26,27,28-Tetrapropoxycalix[4]arene
CAS 147782-22-7C40H48O4
![5,11,17,23-Tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaene-25,26,27,28-tetrol chemical structure, C40H52N4O4, CAS 115421-52-8](/s/CHOMEDBXBPXALL-UHFFFAOYSA-N.svg)
5,11,17,23-Tetrakis[(dimethylamino)methyl]pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaene-25,26,27,28-tetrol
CAS 115421-52-8C40H52N4O4
2,2',2'',2'''-((15,35,55,75-Tetra-tert-butyl-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,32,52,72-tetrayl)tetrakis(oxy))tetraacetic acid
CAS 113215-72-8C52H64O12
Calixarene
CAS 97600-40-3C56H72O12
![2,8,14,20-Tetrapentylcalixresorc[4]arene chemical structure, C48H64O8, CAS 120663-39-0](/s/LRJAHNNLOBUXBG-UHFFFAOYSA-N.svg)
2,8,14,20-Tetrapentylcalixresorc[4]arene
CAS 120663-39-0C48H64O8
![5,11,17,23-Tetrakis(diethylaminomethyl)-2,8,14,20-tetramethylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-4,6,10,12,16,18,22,24-octol chemical structure, C52H76N4O8, CAS 134868-25-0](/s/GKJKJEDPMZXNQP-UHFFFAOYSA-N.svg)
5,11,17,23-Tetrakis(diethylaminomethyl)-2,8,14,20-tetramethylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15,17,19(26),21,23-dodecaene-4,6,10,12,16,18,22,24-octol
CAS 134868-25-0C52H76N4O8
C-Methylcalix(4)resorcinarene
CAS 65338-98-9C32H32O8
C-Undecylcalix(4)resorcinarene Monohydrate
CAS 112247-07-1C72H112O8
![2-[[5,11,17,23-Tetratert-butyl-26,27,28-tris(2-ethoxy-2-oxoethoxy)-25-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3(28),4,6,9,11,13(27),15,17,19(26),21(25),22-dodecaenyl]oxy]acetic acid chemical structure, C58H76O12, CAS 136734-88-8](/s/PQTBXQCIEGVAHL-UHFFFAOYSA-N.svg)
2-[[5,11,17,23-Tetratert-butyl-26,27,28-tris(2-ethoxy-2-oxoethoxy)-25-pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3(28),4,6,9,11,13(27),15,17,19(26),21(25),22-dodecaenyl]oxy]acetic acid
CAS 136734-88-8C58H76O12
Lead ionophore IV
CAS 145237-46-3C60H84N4O4S4
![tert-Butylcalix[4]arene-tetrakis(N,N-dimethylacetamide) chemical structure, C60H84N4O8, CAS 145237-45-2](/s/FTXOVFAXHOOZQB-UHFFFAOYSA-N.svg)
tert-Butylcalix[4]arene-tetrakis(N,N-dimethylacetamide)
CAS 145237-45-2C60H84N4O8
Silver ionophore IV
CAS 145237-25-8C50H68O4S2
15,35,55,75-Tetra-tert-butyl-32,72-bis(prop-2-yn-1-yloxy)-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diol
CAS 178231-98-6C50H60O4
- Agn-PC-0LP50F7233-23-0C34H32O4
- Diethyl 2,2'-((32,72-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetate142267-55-8C36H36O8
- Azaniumylidynetungsten, bis(5,11,17,23-tetratert-butylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(24),3,5,7(28),9,11,13(27),15(26),16,18,21(25),22-dodecaene-25,26,27,28-tetrol)7232-40-8C88H114N2O8W2+2
- 25,26,27,28-Tetramethoxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene99095-68-8C32H32O4
- 26,28-Dihydroxy-25,27-dipropoxycalix(4)arene-5,17-dicarboxaldehyde (cone conformer)163437-36-3C36H36O6
- 26,28-Dimethoxycalix[4]arene-25,27-diol142433-64-5C30H28O4
- 5,17-Diallyl-25,26,27,28-tetrahydroxycalix[4]arene125065-75-0C34H32O4
- 25,26,27,28-Tetrakis(hexyloxy)pentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaen157612-56-1C52H72O4
- p-Chloromethyl-methoxy-calix[4]arene139934-98-8C36H36Cl4O4
- Agn-PC-0NC9AL109051-62-9C28H20N4O12
- O(1),O(3)-Bis(ethoxycarbonylmethyl)-p-tert-butylcalix[4]arene97600-49-2C52H68O8
- 15,35,55,75-Tetraiodo-12,32,52,72-tetrapropoxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane913330-92-4C40H44I4O4
- 25,27-Bis(2-aminoethoxy)-5,11,17,23-tetra-t-butyl-26,28-dihydroxycalix[4]arene154204-25-8C48H66N2O4
- 4-tert-Butyl-calix[4]arene tetra-N-propyl ether126372-90-5C56H80O4
- 1,2,3,4-Tetrakis(methoxycarbonylethoxy)calix[4]arene97600-43-6C44H48O12
- 15,35,55,75-Tetra-tert-butyl-32,52,72-tripropoxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphan-12-ol133301-64-1C53H74O4
- 5,11,17,23-Tetrakis(formyl)-25,26,27,28-tetrahydroxy calix[4]arene266354-15-8C32H24O8
- 2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetyl chloride152442-09-6C48H58Cl2O6
- Dimethyl 2,2'-((15,35,55,75-tetra-tert-butyl-32,72-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))diacetate136157-96-5C50H64O8
- 5,11,17,23-Tetra-t-butyl-25,26,27,28-tetramethoxycalix[4]arene105880-81-7C48H64O4
- 2,2'-((15,35,55,75-Tetra-tert-butyl-32,72-dihydroxy-1,3,5,7(1,3)-tetrabenzenacyclooctaphane-12,52-diyl)bis(oxy))di(acetohydrazide)302956-66-7C48H64N4O6
- Tetrapentyloxy-hydroxycalix[4]arene888496-27-3C48H64O8
- 5,11,17,23-Tetra-t-butyl-25,27-dihydroxy-26,28-dipropoxy-calix[4]arene137693-26-6C50H68O4
- Calix(4)arene281-54-9C28H24
Related scaffolds
Same ring framework with different atoms or bond orders
