Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 16 atoms

31 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 31
With full pages: 4

Scaffold SMILES

c1ccc(Cn2nnc3cncnc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc(Cn2nnc3cncnc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine, 3-[(2-chlorophenyl)methyl]- chemical structure, C11H9ClN6, CAS 832112-89-7

3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine, 3-[(2-chlorophenyl)methyl]-

CAS 832112-89-7C₁₁H₉ClN₆

3-(2-Chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl methyl sulfide chemical structure, C12H10ClN5S, CAS 501370-44-1

3-(2-Chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl methyl sulfide

CAS 501370-44-1C₁₂H₁₀ClN₅S

3-(4-Fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl methyl sulfide chemical structure, C12H10FN5S, CAS 686301-61-1

3-(4-Fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl methyl sulfide

CAS 686301-61-1C₁₂H₁₀FN₅S

3-Benzyl-N-(2-methoxyethyl)triazolo[4,5-d]pyrimidin-7-amine chemical structure, C14H16N6O, CAS 606108-08-1

3-Benzyl-N-(2-methoxyethyl)triazolo[4,5-d]pyrimidin-7-amine

CAS 606108-08-1C₁₄H₁₆N₆O

2-(3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino)-ethanol chemical structure, C13H14N6O, CAS 159599-43-6

2-(3-Benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-ylamino)-ethanol

CAS 159599-43-6C₁₃H₁₄N₆O

3-Benzyl-N-butyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine chemical structure, C15H18N6, CAS 606108-12-7

3-Benzyl-N-butyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine

CAS 606108-12-7C₁₅H₁₈N₆

N,N-Diethyl-2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamide chemical structure, C17H19FN6OS, CAS 863458-08-6

N,N-Diethyl-2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamide

CAS 863458-08-6C₁₇H₁₉FN₆OS

2-[3-[(4-Fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetamide chemical structure, C13H11FN6OS, CAS 863453-17-2

2-[3-[(4-Fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetamide

CAS 863453-17-2C₁₃H₁₁FN₆OS

Ethyl 2-(2-((3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamido)acetate chemical structure, C17H18N6O3S, CAS 896678-12-9

Ethyl 2-(2-((3-benzyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamido)acetate

CAS 896678-12-9C₁₇H₁₈N₆O₃S

1-((3-(4-Methylbenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propan-2-one chemical structure, C15H15N5OS, CAS 896678-24-3

1-((3-(4-Methylbenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propan-2-one

CAS 896678-24-3C₁₅H₁₅N₅OS

Ethyl 2-[[2-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetyl]amino]acetate chemical structure, C17H17FN6O3S, CAS 863457-98-1

Ethyl 2-[[2-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetyl]amino]acetate

CAS 863457-98-1C₁₇H₁₇FN₆O₃S

Methyl 2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetate chemical structure, C14H12FN5O2S, CAS 863458-26-8

Methyl 2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetate

CAS 863458-26-8C₁₄H₁₂FN₅O₂S

Ethyl 2-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetate chemical structure, C15H14FN5O2S, CAS 863458-27-9

Ethyl 2-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetate

CAS 863458-27-9C₁₅H₁₄FN₅O₂S

Ethyl 4-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanyl-3-oxobutanoate chemical structure, C17H16FN5O3S, CAS 863458-32-6

Ethyl 4-[3-[(4-fluorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanyl-3-oxobutanoate

CAS 863458-32-6C₁₇H₁₆FN₅O₃S

Ethyl 2-(2-((3-(2-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamido)acetate chemical structure, C17H17FN6O3S, CAS 863458-82-6

Ethyl 2-(2-((3-(2-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetamido)acetate

CAS 863458-82-6C₁₇H₁₇FN₆O₃S

2-((3-(2-Fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetic acid chemical structure, C13H10FN5O2S, CAS 863459-03-4

2-((3-(2-Fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)acetic acid

CAS 863459-03-4C₁₃H₁₀FN₅O₂S

Ethyl 2-[3-[(4-chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetate chemical structure, C15H14ClN5O2S, CAS 896678-47-0

Ethyl 2-[3-[(4-chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylacetate

CAS 896678-47-0C₁₅H₁₄ClN₅O₂S

1-[3-[(4-Chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylpropan-2-one chemical structure, C14H12ClN5OS, CAS 941911-63-3

1-[3-[(4-Chlorophenyl)methyl]triazolo[4,5-d]pyrimidin-7-yl]sulfanylpropan-2-one

CAS 941911-63-3C₁₄H₁₂ClN₅OS

3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-3-[(2-fluorophenyl)methyl]- chemical structure, C11H7ClFN5, CAS 119222-29-6

3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-3-[(2-fluorophenyl)methyl]-

CAS 119222-29-6C₁₁H₇ClFN₅

3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-3-[(2-chlorophenyl)methyl]- chemical structure, C11H7Cl2N5, CAS 201541-70-0

3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-3-[(2-chlorophenyl)methyl]-

CAS 201541-70-0C₁₁H₇Cl₂N₅

3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C11H8ClN5, CAS 21410-06-0

3-Benzyl-7-chloro-3H-[1,2,3]triazolo[4,5-d]pyrimidine

CAS 21410-06-0C₁₁H₈ClN₅

Ethyl 2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propanoate chemical structure, C16H16FN5O2S, CAS 863458-28-0

Ethyl 2-((3-(4-fluorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propanoate

CAS 863458-28-0C₁₆H₁₆FN₅O₂S

Ethyl 2-((3-(4-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propanoate chemical structure, C16H16ClN5O2S, CAS 896678-49-2

Ethyl 2-((3-(4-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)thio)propanoate

CAS 896678-49-2C₁₆H₁₆ClN₅O₂S

3-Benzyl-7-chloro-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C12H10ClN5, CAS 592520-20-2

3-Benzyl-7-chloro-5-methyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine

CAS 592520-20-2C₁₂H₁₀ClN₅