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Murcko scaffold

4-Phenyl-2-pyrrolidinone scaffold

606 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
606
With full pages
51
Scaffold SMILES

O=C1CC(c2ccccc2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-pyrrolidinone page
Murcko scaffold O=C1CC(c2ccccc2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 606 chemicals

4-Phenyl-4-isopropyl-2-pyrrolidone chemical structure, C13H17NO, CAS 22196-68-5
4-Phenyl-4-isopropyl-2-pyrrolidone
CAS 22196-68-5C13H17NO
4-Phenyl-5,5-dicarbethoxy-2-pyrrolidinone chemical structure, C16H19NO5, CAS 13992-75-1
4-Phenyl-5,5-dicarbethoxy-2-pyrrolidinone
CAS 13992-75-1C16H19NO5
4-Phenyl-2-pyrrolidinone chemical structure, C10H11NO, CAS 1198-97-6
4-Phenyl-2-pyrrolidinone
CAS 1198-97-6C10H11NO
Fonturacetam chemical structure, C12H14N2O2, CAS 77472-70-9
Fonturacetam
CAS 77472-70-9C12H14N2O2
4-(4-Chlorophenyl)-2-pyrrolidinone chemical structure, C10H10ClNO, CAS 22518-27-0
4-(4-Chlorophenyl)-2-pyrrolidinone
CAS 22518-27-0C10H10ClNO
Ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate chemical structure, C13H15NO3, CAS 52450-32-5
Ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate
CAS 52450-32-5C13H15NO3
(4R)-4-Phenylpyrrolidin-2-one chemical structure, C10H11NO, CAS 71657-88-0
(4R)-4-Phenylpyrrolidin-2-one
CAS 71657-88-0C10H11NO
Methyl 2-oxo-4-phenylpyrrolidine-3-carboxylate chemical structure, C12H13NO3, CAS 55790-17-5
Methyl 2-oxo-4-phenylpyrrolidine-3-carboxylate
CAS 55790-17-5C12H13NO3
(3S)-5-Oxo-3-phenyl-D-proline ethyl ester chemical structure, C13H15NO3, CAS 246231-99-2
(3S)-5-Oxo-3-phenyl-D-proline ethyl ester
CAS 246231-99-2C13H15NO3
Ethyl (2S,3S)-5-oxo-3-phenylpyrrolidine-2-carboxylate chemical structure, C13H15NO3, CAS 13992-77-3
Ethyl (2S,3S)-5-oxo-3-phenylpyrrolidine-2-carboxylate
CAS 13992-77-3C13H15NO3
(4S)-4-Methyl-4-phenyl-pyrrolidin-2-one chemical structure, C11H13NO, CAS 2070871-52-0
(4S)-4-Methyl-4-phenyl-pyrrolidin-2-one
CAS 2070871-52-0C11H13NO
(3S,4R)-4-(4-Methoxyphenyl)-2-oxo-pyrrolidine-3-carboxylic acid chemical structure, C12H13NO4, CAS 1784747-73-4
(3S,4R)-4-(4-Methoxyphenyl)-2-oxo-pyrrolidine-3-carboxylic acid
CAS 1784747-73-4C12H13NO4
(3R,4S)-4-(4-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid chemical structure, C12H13NO4, CAS 1784747-95-0
(3R,4S)-4-(4-Methoxyphenyl)-2-oxopyrrolidine-3-carboxylic acid
CAS 1784747-95-0C12H13NO4
(S)-4-Phenylpyrrolidin-2-one chemical structure, C10H11NO, CAS 62624-45-7
(S)-4-Phenylpyrrolidin-2-one
CAS 62624-45-7C10H11NO
(3R,4S)-2-Oxo-4-phenylpyrrolidine-3-carboxylic acid chemical structure, C11H11NO3, CAS 71639-15-1
(3R,4S)-2-Oxo-4-phenylpyrrolidine-3-carboxylic acid
CAS 71639-15-1C11H11NO3
(R)-4-(4-Methoxyphenyl)pyrrolidin-2-one chemical structure, C11H13NO2, CAS 894421-65-9
(R)-4-(4-Methoxyphenyl)pyrrolidin-2-one
CAS 894421-65-9C11H13NO2
(S)-4-(4-Methoxyphenyl)pyrrolidin-2-one chemical structure, C11H13NO2, CAS 854777-02-9
(S)-4-(4-Methoxyphenyl)pyrrolidin-2-one
CAS 854777-02-9C11H13NO2
Fonturacetam, (R)- chemical structure, C12H14N2O2, CAS 949925-07-9
Fonturacetam, (R)-
CAS 949925-07-9C12H14N2O2
1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4S)- chemical structure, C12H14N2O2, CAS 949925-08-0
1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4S)-
CAS 949925-08-0C12H14N2O2
Methyl (3R,4S)-4-(4-methoxyphenyl)-2-oxo-pyrrolidine-3-carboxylate chemical structure, C13H15NO4, CAS 1784747-51-8
Methyl (3R,4S)-4-(4-methoxyphenyl)-2-oxo-pyrrolidine-3-carboxylate
CAS 1784747-51-8C13H15NO4
(S)-4-(4-Fluorophenyl)pyrrolidin-2-one chemical structure, C10H10FNO, CAS 2227107-77-7
(S)-4-(4-Fluorophenyl)pyrrolidin-2-one
CAS 2227107-77-7C10H10FNO
Methyl (3R,4S)-2-oxo-4-phenylpyrrolidine-3-carboxylate chemical structure, C12H13NO3, CAS 1784747-50-7
Methyl (3R,4S)-2-oxo-4-phenylpyrrolidine-3-carboxylate
CAS 1784747-50-7C12H13NO3
Methyl (3S,4R)-2-oxo-4-phenylpyrrolidine-3-carboxylate chemical structure, C12H13NO3, CAS 2055104-88-4
Methyl (3S,4R)-2-oxo-4-phenylpyrrolidine-3-carboxylate
CAS 2055104-88-4C12H13NO3
(R)-4-(4-Chlorophenyl)pyrrolidin-2-one chemical structure, C10H10ClNO, CAS 123632-35-9
(R)-4-(4-Chlorophenyl)pyrrolidin-2-one
CAS 123632-35-9C10H10ClNO