CompoundList
Sign in
Murcko scaffold

N-Benzyl-6-hydroxypyrimidine-4-carboxamide scaffold

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
23
With full pages
3
Scaffold SMILES

O=C(NCc1ccccc1)c1cc(=O)[nH]cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzyl-6-hydroxypyrimidine-4-carboxamide page
Murcko scaffold O=C(NCc1ccccc1)c1cc(=O)[nH]cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

2-(2-Aminopropan-2-yl)-4-((4-fluorobenzyl)carbamoyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-5-yl pivalate chemical structure, C21H27FN4O4, CAS 1172131-64-4
2-(2-Aminopropan-2-yl)-4-((4-fluorobenzyl)carbamoyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-5-yl pivalate
CAS 1172131-64-4C21H27FN4O4
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide chemical structure, C16H19FN4O3, CAS 518048-03-8
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
CAS 518048-03-8C16H19FN4O3
Methyl [[1-[4-[[(4-Fluorobenzyl)amino]carbonyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]-1-methylethyl]amino](oxo)acetate chemical structure, C19H21FN4O6, CAS 518048-04-9
Methyl [[1-[4-[[(4-Fluorobenzyl)amino]carbonyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]-1-methylethyl]amino](oxo)acetate
CAS 518048-04-9C19H21FN4O6
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-Amino-2-oxoacetic Acid) Raltegravir chemical structure, C18H19FN4O6, CAS 1064706-98-4
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-Amino-2-oxoacetic Acid) Raltegravir
CAS 1064706-98-4C18H19FN4O6
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide-d3 chemical structure, C16H19FN4O3, CAS 1189508-85-7
2-(1-Amino-1-methylethyl)-N-(4-fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide-d3
CAS 1189508-85-7C16H19FN4O3
Raltegravir EP impurity F chemical structure, C22H27FN6O6
Raltegravir EP impurity F
C22H27FN6O6
Raltegravir potassium impurity F [EP] chemical structure, C22H27FN6O6, CAS 2138805-56-6
Raltegravir potassium impurity F [EP]
CAS 2138805-56-6C22H27FN6O6
Raltegravir -ethoxyacethydrazone chemical structure, C22H27FN6O6
Raltegravir -ethoxyacethydrazone
C22H27FN6O6
Raltegravir amine monohydrate chemical structure, C16H21FN4O4, CAS 1926131-90-9
Raltegravir amine monohydrate
CAS 1926131-90-9C16H21FN4O4
2-[2-(Dimethylamino)propan-2-yl]-N-[(4-fluorophenyl)methyl]-5,6-dihydroxypyrimidine-4-carboxamide chemical structure, C17H21FN4O3, CAS 519028-36-5
2-[2-(Dimethylamino)propan-2-yl]-N-[(4-fluorophenyl)methyl]-5,6-dihydroxypyrimidine-4-carboxamide
CAS 519028-36-5C17H21FN4O3
N-(4-Fluorobenzyl)-6-hydroxypyrimidine-4-carboxamide chemical structure, C12H10FN3O2, CAS 2034447-20-4
N-(4-Fluorobenzyl)-6-hydroxypyrimidine-4-carboxamide
CAS 2034447-20-4C12H10FN3O2
N-Benzyl-6-hydroxypyrimidine-4-carboxamide chemical structure, C12H11N3O2, CAS 2034474-47-8
N-Benzyl-6-hydroxypyrimidine-4-carboxamide
CAS 2034474-47-8C12H11N3O2
N-(4-Chlorobenzyl)-6-hydroxypyrimidine-4-carboxamide chemical structure, C12H10ClN3O2, CAS 2034621-19-5
N-(4-Chlorobenzyl)-6-hydroxypyrimidine-4-carboxamide
CAS 2034621-19-5C12H10ClN3O2
N-(2-Chlorobenzyl)-6-hydroxypyrimidine-4-carboxamide chemical structure, C12H10ClN3O2, CAS 2034621-23-1
N-(2-Chlorobenzyl)-6-hydroxypyrimidine-4-carboxamide
CAS 2034621-23-1C12H10ClN3O2
6-Hydroxy-N-(1-phenylethyl)pyrimidine-4-carboxamide chemical structure, C13H13N3O2, CAS 2034233-40-2
6-Hydroxy-N-(1-phenylethyl)pyrimidine-4-carboxamide
CAS 2034233-40-2C13H13N3O2
6-Hydroxy-N-(2-(trifluoromethoxy)benzyl)pyrimidine-4-carboxamide chemical structure, C13H10F3N3O3, CAS 2034447-73-7
6-Hydroxy-N-(2-(trifluoromethoxy)benzyl)pyrimidine-4-carboxamide
CAS 2034447-73-7C13H10F3N3O3
N-(2,6-Difluorobenzyl)-6-hydroxypyrimidine-4-carboxamide chemical structure, C12H9F2N3O2, CAS 2034226-74-7
N-(2,6-Difluorobenzyl)-6-hydroxypyrimidine-4-carboxamide
CAS 2034226-74-7C12H9F2N3O2
N-(2,4-Dimethoxybenzyl)-6-hydroxypyrimidine-4-carboxamide chemical structure, C14H15N3O4, CAS 2034361-48-1
N-(2,4-Dimethoxybenzyl)-6-hydroxypyrimidine-4-carboxamide
CAS 2034361-48-1C14H15N3O4
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir chemical structure, C19H24FN5O3, CAS 1193687-85-2
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) (E)-2-(N,N-Dimethylformimidamide) Raltegravir
CAS 1193687-85-2C19H24FN5O3
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir chemical structure, C20H23FN6O6, CAS 1391918-17-4
2-Des(5-methyl-1,3,4-oxadiazole-2-carboxamide) 2-(2-(2-Acetylhydrazinyl)-2-oxoacetamide) Raltegravir
CAS 1391918-17-4C20H23FN6O6
N1-[1-[4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]ethanediamide chemical structure, C18H20FN5O5, CAS 1193687-86-3
N1-[1-[4-[[[(4-Fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]ethanediamide
CAS 1193687-86-3C18H20FN5O5
Ethyl 2-[[1-[4-[[[(4-fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]amino]-2-oxoacetate chemical structure, C20H23FN4O6, CAS 1193687-88-5
Ethyl 2-[[1-[4-[[[(4-fluorophenyl)methyl]amino]carbonyl]-1,6-dihydro-5-hydroxy-1-methyl-6-oxo-2-pyrimidinyl]-1-methylethyl]amino]-2-oxoacetate
CAS 1193687-88-5C20H23FN4O6
N-(4-Fluorobenzyl)-2-(2-(2-hydrazineyl-2-oxoacetamido)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide chemical structure, C18H21FN6O5, CAS 2525279-49-4
N-(4-Fluorobenzyl)-2-(2-(2-hydrazineyl-2-oxoacetamido)propan-2-yl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide
CAS 2525279-49-4C18H21FN6O5