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Murcko scaffold

2-((2,5-Diphenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide scaffold

45 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 28
Chemicals: 45
With full pages: 3

Scaffold SMILES

O=C(CSc1nc(-c2ccccc2)[nH]c1-c1ccccc1)NCc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-((2,5-Diphenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide page

Murcko scaffold O=C(CSc1nc(-c2ccccc2)[nH]c1-c1ccccc1)NCc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2-{[2-(3,4-Dimethoxyphenyl)-5-phenyl-1H-imidazol-4-yl]thio}-N-(2-furylmethyl)acetamide chemical structure, C24H23N3O4S, CAS 901233-32-7

2-{[2-(3,4-Dimethoxyphenyl)-5-phenyl-1H-imidazol-4-yl]thio}-N-(2-furylmethyl)acetamide

CAS 901233-32-7C₂₄H₂₃N₃O₄S

N-(Furan-2-ylmethyl)-2-[[2-(3-methoxyphenyl)-5-(4-methoxyphenyl)-1H-imidazol-4-yl]sulfanyl]acetamide chemical structure, C24H23N3O4S, CAS 901257-75-8

N-(Furan-2-ylmethyl)-2-[[2-(3-methoxyphenyl)-5-(4-methoxyphenyl)-1H-imidazol-4-yl]sulfanyl]acetamide

CAS 901257-75-8C₂₄H₂₃N₃O₄S

N-(Furan-2-ylmethyl)-2-[[2-(4-methylsulfanylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl]acetamide chemical structure, C23H21N3O2S2, CAS 901233-47-4

N-(Furan-2-ylmethyl)-2-[[2-(4-methylsulfanylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl]acetamide

CAS 901233-47-4C₂₃H₂₁N₃O₂S₂

2-((5-(3,4-Dimethoxyphenyl)-2-phenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide chemical structure, C24H23N3O4S, CAS 901234-82-0

2-((5-(3,4-Dimethoxyphenyl)-2-phenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide

CAS 901234-82-0C₂₄H₂₃N₃O₄S

2-((2,5-Diphenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide chemical structure, C22H19N3O2S, CAS 901233-02-1

2-((2,5-Diphenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide

CAS 901233-02-1C₂₂H₁₉N₃O₂S

N-[(Furan-2-yl)methyl]-2-{[2-(4-methylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C23H21N3O2S, CAS 901233-07-6

N-[(Furan-2-yl)methyl]-2-{[2-(4-methylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-07-6C₂₃H₂₁N₃O₂S

N-[(Furan-2-yl)methyl]-2-{[2-(3-methylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C23H21N3O2S, CAS 901233-12-3

N-[(Furan-2-yl)methyl]-2-{[2-(3-methylphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-12-3C₂₃H₂₁N₃O₂S

2-((2-(4-Ethylphenyl)-5-phenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide chemical structure, C24H23N3O2S, CAS 901233-17-8

2-((2-(4-Ethylphenyl)-5-phenyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide

CAS 901233-17-8C₂₄H₂₃N₃O₂S

N-[(Furan-2-yl)methyl]-2-{[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C23H21N3O3S, CAS 901233-22-5

N-[(Furan-2-yl)methyl]-2-{[2-(4-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-22-5C₂₃H₂₁N₃O₃S

N-(2-Furylmethyl)-2-{[2-(3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]thio}acetamide chemical structure, C23H21N3O3S, CAS 901233-27-0

N-(2-Furylmethyl)-2-{[2-(3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]thio}acetamide

CAS 901233-27-0C₂₃H₂₁N₃O₃S

2-{[2-(4-Ethoxy-3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C25H25N3O4S, CAS 901233-37-2

2-{[2-(4-Ethoxy-3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-37-2C₂₅H₂₅N₃O₄S

2-{[2-(4-Ethoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C24H23N3O3S, CAS 901233-42-9

2-{[2-(4-Ethoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-42-9C₂₄H₂₃N₃O₃S

2-{[2-(4-Fluorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C22H18FN3O2S, CAS 901233-53-2

2-{[2-(4-Fluorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-53-2C₂₂H₁₈FN₃O₂S

2-{[2-(3-Fluorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C22H18FN3O2S, CAS 901233-59-8

2-{[2-(3-Fluorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-59-8C₂₂H₁₈FN₃O₂S

2-{[2-(4-Chlorophenyl)-5-phenyl-1H-imidazol-4-yl]thio}-N-(2-furylmethyl)acetamide chemical structure, C22H18ClN3O2S, CAS 901233-64-5

2-{[2-(4-Chlorophenyl)-5-phenyl-1H-imidazol-4-yl]thio}-N-(2-furylmethyl)acetamide

CAS 901233-64-5C₂₂H₁₈ClN₃O₂S

2-{[2-(3-Chlorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C22H18ClN3O2S, CAS 931938-39-5

2-{[2-(3-Chlorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 931938-39-5C₂₂H₁₈ClN₃O₂S

N-[(Furan-2-yl)methyl]-2-{[5-(4-methylphenyl)-2-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C23H21N3O2S, CAS 901233-69-0

N-[(Furan-2-yl)methyl]-2-{[5-(4-methylphenyl)-2-phenyl-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-69-0C₂₃H₂₁N₃O₂S

2-((2,5-di-p-Tolyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide chemical structure, C24H23N3O2S, CAS 901233-74-7

2-((2,5-di-p-Tolyl-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide

CAS 901233-74-7C₂₄H₂₃N₃O₂S

2-{[2-(4-Ethylphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C25H25N3O2S, CAS 901233-78-1

2-{[2-(4-Ethylphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-78-1C₂₅H₂₅N₃O₂S

N-[(Furan-2-yl)methyl]-2-{[2-(4-methoxyphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C24H23N3O3S, CAS 901233-82-7

N-[(Furan-2-yl)methyl]-2-{[2-(4-methoxyphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-82-7C₂₄H₂₃N₃O₃S

N-[(Furan-2-yl)methyl]-2-{[2-(3-methoxyphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}acetamide chemical structure, C24H23N3O3S, CAS 901233-87-2

N-[(Furan-2-yl)methyl]-2-{[2-(3-methoxyphenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}acetamide

CAS 901233-87-2C₂₄H₂₃N₃O₃S

2-((2-(3,4-Dimethoxyphenyl)-5-(p-tolyl)-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide chemical structure, C25H25N3O4S, CAS 901233-92-9

2-((2-(3,4-Dimethoxyphenyl)-5-(p-tolyl)-1H-imidazol-4-yl)thio)-N-(furan-2-ylmethyl)acetamide

CAS 901233-92-9C₂₅H₂₅N₃O₄S

2-{[2-(4-Fluorophenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C23H20FN3O2S, CAS 901233-97-4

2-{[2-(4-Fluorophenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901233-97-4C₂₃H₂₀FN₃O₂S

2-{[2-(4-Chlorophenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide chemical structure, C23H20ClN3O2S, CAS 901234-02-4

2-{[2-(4-Chlorophenyl)-5-(4-methylphenyl)-1H-imidazol-4-yl]sulfanyl}-N-[(furan-2-yl)methyl]acetamide

CAS 901234-02-4C₂₃H₂₀ClN₃O₂S