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Murcko scaffold

Ring system with 4 rings and 28 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
5
With full pages
2
Scaffold SMILES

O=C(C=Cc1cn(-c2ccccc2)nc1-c1ccccc1)NCc1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cn(-c2ccccc2)nc1-c1ccccc1)NCc1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

3-(3-(4-Bromophenyl)-1-PH-1H-pyrazol-4-yl)-2-cyano-N-(2-furylmethyl)acrylamide chemical structure, C24H17BrN4O2, CAS 769143-62-6
3-(3-(4-Bromophenyl)-1-PH-1H-pyrazol-4-yl)-2-cyano-N-(2-furylmethyl)acrylamide
CAS 769143-62-6C24H17BrN4O2
2-Cyano-N-(2-furylmethyl)-3-(3-(3-nitrophenyl)-1-PH-1H-pyrazol-4-yl)acrylamide chemical structure, C24H17N5O4, CAS 769143-60-4
2-Cyano-N-(2-furylmethyl)-3-(3-(3-nitrophenyl)-1-PH-1H-pyrazol-4-yl)acrylamide
CAS 769143-60-4C24H17N5O4
(E)-2-Cyano-N-(furan-2-ylmethyl)-3-[3-[4-(3-methylbutoxy)phenyl]-1-phenylpyrazol-4-yl]prop-2-enamide chemical structure, C29H28N4O3, CAS 380867-90-3
(E)-2-Cyano-N-(furan-2-ylmethyl)-3-[3-[4-(3-methylbutoxy)phenyl]-1-phenylpyrazol-4-yl]prop-2-enamide
CAS 380867-90-3C29H28N4O3
(Z)-2-Cyano-3-[3-(3,4-dimethoxyphenyl)-1-phenylpyrazol-4-yl]-N-(furan-2-ylmethyl)prop-2-enamide chemical structure, C26H22N4O4, CAS 1019064-68-6
(Z)-2-Cyano-3-[3-(3,4-dimethoxyphenyl)-1-phenylpyrazol-4-yl]-N-(furan-2-ylmethyl)prop-2-enamide
CAS 1019064-68-6C26H22N4O4
(E)-2-Cyano-N-(furan-2-ylmethyl)-3-[1-phenyl-3-(4-propoxyphenyl)pyrazol-4-yl]prop-2-enamide chemical structure, C27H24N4O3, CAS 882220-49-7
(E)-2-Cyano-N-(furan-2-ylmethyl)-3-[1-phenyl-3-(4-propoxyphenyl)pyrazol-4-yl]prop-2-enamide
CAS 882220-49-7C27H24N4O3