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Murcko scaffold

2,5-Diphenylthiophene scaffold

74 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
74
With full pages
8
Scaffold SMILES

c1ccc(-c2ccc(-c3ccccc3)s2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Diphenylthiophene page
Murcko scaffold c1ccc(-c2ccc(-c3ccccc3)s2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 74 chemicals

2,5-Diphenylthiophene chemical structure, C16H12S, CAS 1445-78-9
2,5-Diphenylthiophene
CAS 1445-78-9C16H12S
2,5-Bis(4-bromophenyl)thiophene chemical structure, C16H10Br2S, CAS 63574-85-6
2,5-Bis(4-bromophenyl)thiophene
CAS 63574-85-6C16H10Br2S
3-Nitro-2,5-bis(2,4,6-trinitrophenyl)thiophene chemical structure, C16H5N7O14S, CAS 59776-85-1
3-Nitro-2,5-bis(2,4,6-trinitrophenyl)thiophene
CAS 59776-85-1C16H5N7O14S
4-[5-(4-Carbamimidoylphenyl)-2-thienyl]benzamidine chemical structure, C18H16N4S, CAS 73819-28-0
4-[5-(4-Carbamimidoylphenyl)-2-thienyl]benzamidine
CAS 73819-28-0C18H16N4S
2,5-Bis(4-methoxyphenyl)thiophene chemical structure, C18H16O2S, CAS 55827-09-3
2,5-Bis(4-methoxyphenyl)thiophene
CAS 55827-09-3C18H16O2S
2,5-Bis(4-chlorophenyl)thiophene chemical structure, C16H10Cl2S, CAS 82366-97-0
2,5-Bis(4-chlorophenyl)thiophene
CAS 82366-97-0C16H10Cl2S
4,4'-(Thiophene-2,5-diyl)dibenzonitrile chemical structure, C18H10N2S, CAS 55368-38-2
4,4'-(Thiophene-2,5-diyl)dibenzonitrile
CAS 55368-38-2C18H10N2S
2,5-Bis(4-nitrophenyl)thiophene chemical structure, C16H10N2O4S, CAS 70010-47-8
2,5-Bis(4-nitrophenyl)thiophene
CAS 70010-47-8C16H10N2O4S
2,5-Bis(4-fluorophenyl)thiophene chemical structure, C16H10F2S, CAS 883793-48-4
2,5-Bis(4-fluorophenyl)thiophene
CAS 883793-48-4C16H10F2S
Thiophene, 3,4-diethyl-2,5-diphenyl- chemical structure, C20H20S, CAS 101306-10-9
Thiophene, 3,4-diethyl-2,5-diphenyl-
CAS 101306-10-9C20H20S
Benzonitrile, 4-[5-(4-methylphenyl)-2-thienyl]- chemical structure, C18H13NS, CAS 51775-50-9
Benzonitrile, 4-[5-(4-methylphenyl)-2-thienyl]-
CAS 51775-50-9C18H13NS
2-(4-Bromophenyl)-5-phenylthiophene chemical structure, C16H11BrS, CAS 118621-30-0
2-(4-Bromophenyl)-5-phenylthiophene
CAS 118621-30-0C16H11BrS
Thiophene, 2-(4-methylphenyl)-5-(4-nitrophenyl)- chemical structure, C17H13NO2S, CAS 61100-20-7
Thiophene, 2-(4-methylphenyl)-5-(4-nitrophenyl)-
CAS 61100-20-7C17H13NO2S
2-(4-Methylphenyl)-5-phenylthiophene chemical structure, C17H14S, CAS 158954-03-1
2-(4-Methylphenyl)-5-phenylthiophene
CAS 158954-03-1C17H14S
Thiophene, 2-(4-nitrophenyl)-5-phenyl- chemical structure, C16H11NO2S, CAS 51776-05-7
Thiophene, 2-(4-nitrophenyl)-5-phenyl-
CAS 51776-05-7C16H11NO2S
Methyl 2,5-diphenylthiophene-3-carboxylate chemical structure, C18H14O2S, CAS 20851-12-1
Methyl 2,5-diphenylthiophene-3-carboxylate
CAS 20851-12-1C18H14O2S
2-(5-Phenyl-2-thienyl)benzoic acid chemical structure, C17H12O2S, CAS 58268-06-7
2-(5-Phenyl-2-thienyl)benzoic acid
CAS 58268-06-7C17H12O2S
3,4-Thiophenedicarboxaldehyde, 2,5-diphenyl- chemical structure, C18H12O2S, CAS 59611-35-7
3,4-Thiophenedicarboxaldehyde, 2,5-diphenyl-
CAS 59611-35-7C18H12O2S
3,4-Thiophenedimethanol, 2,5-diphenyl- chemical structure, C18H16O2S, CAS 59611-38-0
3,4-Thiophenedimethanol, 2,5-diphenyl-
CAS 59611-38-0C18H16O2S
Thiophene, 2,5-bis(2,4-dinitrophenyl)- chemical structure, C16H8N4O8S, CAS 61200-48-4
Thiophene, 2,5-bis(2,4-dinitrophenyl)-
CAS 61200-48-4C16H8N4O8S
Acetamide, N-[4-[5-(4-methylphenyl)-2-thienyl]phenyl]- chemical structure, C19H17NOS, CAS 61100-21-8
Acetamide, N-[4-[5-(4-methylphenyl)-2-thienyl]phenyl]-
CAS 61100-21-8C19H17NOS
2,5-Bis(4-methylphenyl)thiophene chemical structure, C18H16S, CAS 82366-98-1
2,5-Bis(4-methylphenyl)thiophene
CAS 82366-98-1C18H16S
2,5-Diphenyl-3-thiophenethiol chemical structure, C16H12S2, CAS 101306-13-2
2,5-Diphenyl-3-thiophenethiol
CAS 101306-13-2C16H12S2
2,5-Bis(2-formylphenyl)thiophene chemical structure, C18H12O2S, CAS 107793-02-2
2,5-Bis(2-formylphenyl)thiophene
CAS 107793-02-2C18H12O2S