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Murcko scaffold

2-Phenyl-1-(2-thienyl)ethanone scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
17
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-1-(2-thienyl)ethanone page
Murcko scaffold O=C(Cc1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-Phenyl-1-(2-thienyl)ethanone chemical structure, C12H10OS, CAS 13196-28-6
2-Phenyl-1-(2-thienyl)ethanone
CAS 13196-28-6C12H10OS
1-(5-Bromothiophen-2-yl)-2-phenylethan-1-one chemical structure, C12H9BrOS, CAS 56824-81-8
1-(5-Bromothiophen-2-yl)-2-phenylethan-1-one
CAS 56824-81-8C12H9BrOS
2-(4-Isobutylphenyl)-1-(2-thienyl)propan-1-one chemical structure, C17H20OS, CAS 261178-32-9
2-(4-Isobutylphenyl)-1-(2-thienyl)propan-1-one
CAS 261178-32-9C17H20OS
2-(4-Bromophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile chemical structure, C13H8BrNOS, CAS 561305-83-7
2-(4-Bromophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile
CAS 561305-83-7C13H8BrNOS
2-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile chemical structure, C13H7Cl2NOS, CAS 561305-84-8
2-(2,4-Dichlorophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile
CAS 561305-84-8C13H7Cl2NOS
2-Phenyl-1-(2-thienyl)-1,4-pentanedione chemical structure, C15H14O2S, CAS 59086-29-2
2-Phenyl-1-(2-thienyl)-1,4-pentanedione
CAS 59086-29-2C15H14O2S
1-(3-Bromo-2-thienyl)-2-(2-nitrophenyl)ethanone chemical structure, C12H8BrNO3S, CAS 38078-79-4
1-(3-Bromo-2-thienyl)-2-(2-nitrophenyl)ethanone
CAS 38078-79-4C12H8BrNO3S
4-[2-Oxo-2-(thiophen-2-yl)ethyl]benzonitrile chemical structure, C13H9NOS, CAS 90013-81-3
4-[2-Oxo-2-(thiophen-2-yl)ethyl]benzonitrile
CAS 90013-81-3C13H9NOS
2-(4-Chlorophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile chemical structure, C13H8ClNOS, CAS 96514-30-6
2-(4-Chlorophenyl)-3-oxo-3-(thiophen-2-yl)propanenitrile
CAS 96514-30-6C13H8ClNOS
4-Acetoxybenzyl 2-thienyl ketone chemical structure, C14H12O3S, CAS 126496-55-7
4-Acetoxybenzyl 2-thienyl ketone
CAS 126496-55-7C14H12O3S
[2-(2-Oxo-2-thiophen-2-ylethyl)phenyl] acetate chemical structure, C14H12O3S, CAS 898766-62-6
[2-(2-Oxo-2-thiophen-2-ylethyl)phenyl] acetate
CAS 898766-62-6C14H12O3S
[3-(2-Oxo-2-thiophen-2-ylethyl)phenyl] acetate chemical structure, C14H12O3S, CAS 898766-65-9
[3-(2-Oxo-2-thiophen-2-ylethyl)phenyl] acetate
CAS 898766-65-9C14H12O3S
2-(2-Chlorophenyl)-1-(thiophen-2-yl)ethan-1-one chemical structure, C12H9ClOS, CAS 1094251-98-5
2-(2-Chlorophenyl)-1-(thiophen-2-yl)ethan-1-one
CAS 1094251-98-5C12H9ClOS
Ketone, benzyl 5-ethyl-2-thienyl (5CI) chemical structure, C14H14OS, CAS 651328-51-7
Ketone, benzyl 5-ethyl-2-thienyl (5CI)
CAS 651328-51-7C14H14OS
1-(5-Chloro-2-thienyl)-2-phenylethanone chemical structure, C12H9ClOS, CAS 651291-53-1
1-(5-Chloro-2-thienyl)-2-phenylethanone
CAS 651291-53-1C12H9ClOS
1-(3-Methylthiophen-2-yl)-2-phenylethan-1-one chemical structure, C13H12OS, CAS 1184270-90-3
1-(3-Methylthiophen-2-yl)-2-phenylethan-1-one
CAS 1184270-90-3C13H12OS
2-(3-Chlorophenyl)-1-(5-chlorothiophen-2-yl)ethanone chemical structure, C12H8Cl2OS, CAS 1248289-00-0
2-(3-Chlorophenyl)-1-(5-chlorothiophen-2-yl)ethanone
CAS 1248289-00-0C12H8Cl2OS