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Murcko scaffold

Ring system with 2 rings and 26 atoms

39 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 26
Chemicals: 39
With full pages: 7

Scaffold SMILES

O=C(COC(=O)CNS(=O)(=O)C=Cc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(COC(=O)CNS(=O)(=O)C=Cc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

{[2-(Difluoromethoxy)phenyl]carbamoyl}methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C19H18F2N2O6S, CAS 735291-42-6

{[2-(Difluoromethoxy)phenyl]carbamoyl}methyl 2-(2-phenylethenesulfonamido)acetate

CAS 735291-42-6C₁₉H₁₈F₂N₂O₆S

[(2-Ethyl-6-methylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C21H24N2O5S, CAS 731827-53-5

[(2-Ethyl-6-methylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731827-53-5C₂₁H₂₄N₂O₅S

[(3,5-Dimethoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C20H22N2O7S, CAS 731827-71-7

[(3,5-Dimethoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731827-71-7C₂₀H₂₂N₂O₇S

[(2,6-Dichloro-3-methylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C19H18Cl2N2O5S, CAS 731827-75-1

[(2,6-Dichloro-3-methylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731827-75-1C₁₉H₁₈Cl₂N₂O₅S

[(5-tert-Butyl-2-methoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C23H28N2O6S, CAS 731829-03-1

[(5-tert-Butyl-2-methoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731829-03-1C₂₃H₂₈N₂O₆S

[(3,4-Dimethoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C20H22N2O7S, CAS 733795-89-6

[(3,4-Dimethoxyphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 733795-89-6C₂₀H₂₂N₂O₇S

[2-(4-Fluoro-2-nitroanilino)-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate chemical structure, C18H16FN3O7S, CAS 742112-59-0

[2-(4-Fluoro-2-nitroanilino)-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate

CAS 742112-59-0C₁₈H₁₆FN₃O₇S

[2-[4-Chloro-3-(dimethylsulfamoyl)anilino]-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate chemical structure, C20H22ClN3O7S2, CAS 731828-82-3

[2-[4-Chloro-3-(dimethylsulfamoyl)anilino]-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate

CAS 731828-82-3C₂₀H₂₂ClN₃O₇S₂

[(4-Ethoxy-2-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C20H21N3O8S, CAS 731829-55-3

[(4-Ethoxy-2-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731829-55-3C₂₀H₂₁N₃O₈S

[(5-Methoxy-2-methyl-4-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C20H21N3O8S, CAS 731829-04-2

[(5-Methoxy-2-methyl-4-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 731829-04-2C₂₀H₂₁N₃O₈S

[(2,5-Dimethoxyphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C21H24N2O7S, CAS 852685-23-5

[(2,5-Dimethoxyphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 852685-23-5C₂₁H₂₄N₂O₇S

{[4-(Trifluoromethoxy)phenyl]carbamoyl}methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C20H19F3N2O6S, CAS 852685-41-7

{[4-(Trifluoromethoxy)phenyl]carbamoyl}methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 852685-41-7C₂₀H₁₉F₃N₂O₆S

[(2,5-Dimethylphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C21H24N2O5S, CAS 853340-16-6

[(2,5-Dimethylphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 853340-16-6C₂₁H₂₄N₂O₅S

[2-[4-(Diethylsulfamoyl)anilino]-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate chemical structure, C22H27N3O7S2, CAS 1164507-96-3

[2-[4-(Diethylsulfamoyl)anilino]-2-oxoethyl] 2-[[(E)-2-phenylethenyl]sulfonylamino]acetate

CAS 1164507-96-3C₂₂H₂₇N₃O₇S₂

1-[(2-Chloro-4-nitrophenyl)carbamoyl]ethyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C20H20ClN3O7S, CAS 792961-74-1

1-[(2-Chloro-4-nitrophenyl)carbamoyl]ethyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 792961-74-1C₂₀H₂₀ClN₃O₇S

{[4-(Trifluoromethoxy)phenyl]carbamoyl}methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C19H17F3N2O6S, CAS 848332-82-1

{[4-(Trifluoromethoxy)phenyl]carbamoyl}methyl 2-(2-phenylethenesulfonamido)acetate

CAS 848332-82-1C₁₉H₁₇F₃N₂O₆S

[2-[4-Chloro-3-(trifluoromethyl)anilino]-2-oxoethyl] 2-[[(E)-2-(4-methylphenyl)ethenyl]sulfonylamino]acetate chemical structure, C20H18ClF3N2O5S, CAS 849011-85-4

[2-[4-Chloro-3-(trifluoromethyl)anilino]-2-oxoethyl] 2-[[(E)-2-(4-methylphenyl)ethenyl]sulfonylamino]acetate

CAS 849011-85-4C₂₀H₁₈ClF₃N₂O₅S

1-{[4-(Trifluoromethyl)phenyl]carbamoyl}ethyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C20H19F3N2O5S, CAS 869872-33-3

1-{[4-(Trifluoromethyl)phenyl]carbamoyl}ethyl 2-(2-phenylethenesulfonamido)acetate

CAS 869872-33-3C₂₀H₁₉F₃N₂O₅S

[(3-Sulfamoylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C18H19N3O7S2, CAS 875301-07-8

[(3-Sulfamoylphenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 875301-07-8C₁₈H₁₉N₃O₇S₂

[(4-Fluoro-3-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate chemical structure, C18H16FN3O7S, CAS 875300-68-8

[(4-Fluoro-3-nitrophenyl)carbamoyl]methyl 2-(2-phenylethenesulfonamido)acetate

CAS 875300-68-8C₁₈H₁₆FN₃O₇S

[(4-Bromo-2-fluorophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C19H18BrFN2O5S, CAS 878081-06-2

[(4-Bromo-2-fluorophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 878081-06-2C₁₉H₁₈BrFN₂O₅S

[(2-Chloro-4-fluorophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C19H18ClFN2O5S, CAS 878081-12-0

[(2-Chloro-4-fluorophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 878081-12-0C₁₉H₁₈ClFN₂O₅S

[(2-Ethoxyphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C21H24N2O6S, CAS 878081-18-6

[(2-Ethoxyphenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 878081-18-6C₂₁H₂₄N₂O₆S

[(3-Chloro-4-cyanophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate chemical structure, C20H18ClN3O5S, CAS 878083-59-1

[(3-Chloro-4-cyanophenyl)carbamoyl]methyl 2-[2-(4-methylphenyl)ethenesulfonamido]acetate

CAS 878083-59-1C₂₀H₁₈ClN₃O₅S