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Murcko scaffold

Acetamide, N,N'-1,2-ethanediylbis[2-phenoxy- scaffold

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
24
Chemicals
23
With full pages
3
Scaffold SMILES

O=C(COc1ccccc1)NCCNC(=O)COc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Acetamide, N,N'-1,2-ethanediylbis[2-phenoxy- page
Murcko scaffold O=C(COc1ccccc1)NCCNC(=O)COc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

Acetamide, N,N'-1,2-ethanediylbis[2-phenoxy- chemical structure, C18H20N2O4, CAS 89806-94-0
Acetamide, N,N'-1,2-ethanediylbis[2-phenoxy-
CAS 89806-94-0C18H20N2O4
2-(4-Methylphenoxy)-N-[2-[[2-(4-methylphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C20H24N2O4, CAS 327071-22-7
2-(4-Methylphenoxy)-N-[2-[[2-(4-methylphenoxy)acetyl]amino]ethyl]acetamide
CAS 327071-22-7C20H24N2O4
2-(3-Methylphenoxy)-N-[2-[[2-(3-methylphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C20H24N2O4, CAS 355437-21-7
2-(3-Methylphenoxy)-N-[2-[[2-(3-methylphenoxy)acetyl]amino]ethyl]acetamide
CAS 355437-21-7C20H24N2O4
2-(4-Chloro-2-methylphenoxy)-N-[2-[[2-(4-chloro-2-methylphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C20H22Cl2N2O4, CAS 327071-43-2
2-(4-Chloro-2-methylphenoxy)-N-[2-[[2-(4-chloro-2-methylphenoxy)acetyl]amino]ethyl]acetamide
CAS 327071-43-2C20H22Cl2N2O4
2-(3,5-Dimethylphenoxy)-N-[2-[[2-(3,5-dimethylphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C22H28N2O4, CAS 398488-24-9
2-(3,5-Dimethylphenoxy)-N-[2-[[2-(3,5-dimethylphenoxy)acetyl]amino]ethyl]acetamide
CAS 398488-24-9C22H28N2O4
2-(4-Methoxyphenoxy)-N-[2-[[2-(4-methoxyphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C20H24N2O6, CAS 424809-49-4
2-(4-Methoxyphenoxy)-N-[2-[[2-(4-methoxyphenoxy)acetyl]amino]ethyl]acetamide
CAS 424809-49-4C20H24N2O6
2-(2-Methylphenoxy)-N-[2-[[2-(2-methylphenoxy)acetyl]amino]propyl]acetamide chemical structure, C21H26N2O4, CAS 327065-52-1
2-(2-Methylphenoxy)-N-[2-[[2-(2-methylphenoxy)acetyl]amino]propyl]acetamide
CAS 327065-52-1C21H26N2O4
2-(4-Chloro-2-methylphenoxy)-N-(2-{[(4-chloro-2-methylphenoxy)acetyl]amino}-1-methylethyl)acetamide chemical structure, C21H24Cl2N2O4, CAS 327071-48-7
2-(4-Chloro-2-methylphenoxy)-N-(2-{[(4-chloro-2-methylphenoxy)acetyl]amino}-1-methylethyl)acetamide
CAS 327071-48-7C21H24Cl2N2O4
2-(4-Chlorophenoxy)-N-[2-[[2-(4-chlorophenoxy)acetyl]amino]propyl]acetamide chemical structure, C19H20Cl2N2O4, CAS 315675-75-3
2-(4-Chlorophenoxy)-N-[2-[[2-(4-chlorophenoxy)acetyl]amino]propyl]acetamide
CAS 315675-75-3C19H20Cl2N2O4
2-(4-Methylphenoxy)-N-[2-[[2-(4-methylphenoxy)acetyl]amino]propyl]acetamide chemical structure, C21H26N2O4, CAS 315676-10-9
2-(4-Methylphenoxy)-N-[2-[[2-(4-methylphenoxy)acetyl]amino]propyl]acetamide
CAS 315676-10-9C21H26N2O4
2-(2-Methoxyphenoxy)-N-[2-[[2-(2-methoxyphenoxy)acetyl]amino]propyl]acetamide chemical structure, C21H26N2O6, CAS 433326-55-7
2-(2-Methoxyphenoxy)-N-[2-[[2-(2-methoxyphenoxy)acetyl]amino]propyl]acetamide
CAS 433326-55-7C21H26N2O6
2-(4-tert-Butylphenoxy)-N-[2-[[2-(4-tert-butylphenoxy)acetyl]amino]propyl]acetamide chemical structure, C27H38N2O4, CAS 494830-68-1
2-(4-tert-Butylphenoxy)-N-[2-[[2-(4-tert-butylphenoxy)acetyl]amino]propyl]acetamide
CAS 494830-68-1C27H38N2O4
N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide) chemical structure, C26H36N2O4, CAS 494830-67-0
N,N'-(Ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)
CAS 494830-67-0C26H36N2O4
2-(4-Chloro-2-methylphenoxy)-N-[2-[2-(4-chloro-2-methylphenoxy)propanoylamino]ethyl]propanamide chemical structure, C22H26Cl2N2O4, CAS 547728-21-2
2-(4-Chloro-2-methylphenoxy)-N-[2-[2-(4-chloro-2-methylphenoxy)propanoylamino]ethyl]propanamide
CAS 547728-21-2C22H26Cl2N2O4
2-Phenoxy-N-[2-(2-phenoxybutanoylamino)ethyl]butanamide chemical structure, C22H28N2O4, CAS 548482-41-3
2-Phenoxy-N-[2-(2-phenoxybutanoylamino)ethyl]butanamide
CAS 548482-41-3C22H28N2O4
2-(2,6-Dimethylphenoxy)-N-[2-[[2-(2,6-dimethylphenoxy)acetyl]amino]ethyl]acetamide chemical structure, C22H28N2O4, CAS 651294-97-2
2-(2,6-Dimethylphenoxy)-N-[2-[[2-(2,6-dimethylphenoxy)acetyl]amino]ethyl]acetamide
CAS 651294-97-2C22H28N2O4
Acetamide, N,N'-1,2-ethanediylbis[2-(2,4-dichlorophenoxy)- chemical structure, C18H16Cl4N2O4, CAS 141776-92-3
Acetamide, N,N'-1,2-ethanediylbis[2-(2,4-dichlorophenoxy)-
CAS 141776-92-3C18H16Cl4N2O4
N,N'-Propane-1,2-diylbis[2-(4-bromophenoxy)acetamide] chemical structure, C19H20Br2N2O4, CAS 446826-26-2
N,N'-Propane-1,2-diylbis[2-(4-bromophenoxy)acetamide]
CAS 446826-26-2C19H20Br2N2O4
2-(4-Fluorophenoxy)-N-[2-[[2-(4-fluorophenoxy)acetyl]amino]ethyl]acetamide chemical structure, C18H18F2N2O4, CAS 865270-98-0
2-(4-Fluorophenoxy)-N-[2-[[2-(4-fluorophenoxy)acetyl]amino]ethyl]acetamide
CAS 865270-98-0C18H18F2N2O4
Acetamide, N,N'-1,2-ethanediylbis[2-(2-nitrophenoxy)- chemical structure, C18H18N4O8, CAS 97848-25-4
Acetamide, N,N'-1,2-ethanediylbis[2-(2-nitrophenoxy)-
CAS 97848-25-4C18H18N4O8
2-Phenoxy-N-[2-[(2-phenoxyacetyl)amino]propyl]acetamide chemical structure, C19H22N2O4, CAS 327059-04-1
2-Phenoxy-N-[2-[(2-phenoxyacetyl)amino]propyl]acetamide
CAS 327059-04-1C19H22N2O4
N,N'-(Ethane-1,2-diyl)bis[2-(2-formylphenoxy)acetamide] chemical structure, C20H20N2O6, CAS 141944-98-1
N,N'-(Ethane-1,2-diyl)bis[2-(2-formylphenoxy)acetamide]
CAS 141944-98-1C20H20N2O6
N,N'-(Ethane-1,2-diyl)bis(N-methyl-2-phenoxyacetamide) chemical structure, C20H24N2O4, CAS 89806-95-1
N,N'-(Ethane-1,2-diyl)bis(N-methyl-2-phenoxyacetamide)
CAS 89806-95-1C20H24N2O4