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Murcko scaffold

Ring system with 2 rings and 9 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
11
With full pages
6
Scaffold SMILES

C1=COc2n[nH]cc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=COc2n[nH]cc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

6-Amino-3-ethyl-4-isopropyl-2,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C12H16N4O, CAS 496771-70-1
6-Amino-3-ethyl-4-isopropyl-2,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile
CAS 496771-70-1C12H16N4O
6-Amino-3,4-dipropyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C13H18N4O, CAS 612513-77-6
6-Amino-3,4-dipropyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 612513-77-6C13H18N4O
6-Amino-3,4-diisopropyl-2,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C13H18N4O, CAS 499210-47-8
6-Amino-3,4-diisopropyl-2,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile
CAS 499210-47-8C13H18N4O
6-Amino-3-tert-butyl-4-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C14H20N4O, CAS 497079-88-6
6-Amino-3-tert-butyl-4-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 497079-88-6C14H20N4O
6-Amino-3-(methoxymethyl)-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C12H16N4O2, CAS 445391-05-9
6-Amino-3-(methoxymethyl)-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 445391-05-9C12H16N4O2
Ethyl 2-(6-amino-5-cyano-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)acetate chemical structure, C14H18N4O3, CAS 445391-06-0
Ethyl 2-(6-amino-5-cyano-4-propan-2-yl-2,4-dihydropyrano[2,3-c]pyrazol-3-yl)acetate
CAS 445391-06-0C14H18N4O3
6-Amino-4-isopropyl-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C13H18N4O, CAS 337500-49-9
6-Amino-4-isopropyl-3-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 337500-49-9C13H18N4O
6-Amino-3-methyl-4-(2-methylpropyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C12H16N4O, CAS 275360-71-9
6-Amino-3-methyl-4-(2-methylpropyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 275360-71-9C12H16N4O
6-Amino-3-methyl-4-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C11H14N4O, CAS 612513-58-3
6-Amino-3-methyl-4-propyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 612513-58-3C11H14N4O
6-Amino-4-ethyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C10H12N4O, CAS 612513-75-4
6-Amino-4-ethyl-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 612513-75-4C10H12N4O
6-Amino-3-methyl-4-nonyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile chemical structure, C17H26N4O, CAS 402953-87-1
6-Amino-3-methyl-4-nonyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
CAS 402953-87-1C17H26N4O