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Murcko scaffold

Ring system with 2 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
8
With full pages
3
Scaffold SMILES

O=c1nc(NN=Cc2ccccc2)cn[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1nc(NN=Cc2ccccc2)cn[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-Nitrobenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone chemical structure, C11H10N6O3, CAS 6144-43-0
2-Nitrobenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone
CAS 6144-43-0C11H10N6O3
(E)-5-(2-(4-(Dimethylamino)benzylidene)hydrazinyl)-6-methyl-1,2,4-triazin-3(2H)-one chemical structure, C13H16N6O, CAS 463958-16-9
(E)-5-(2-(4-(Dimethylamino)benzylidene)hydrazinyl)-6-methyl-1,2,4-triazin-3(2H)-one
CAS 463958-16-9C13H16N6O
3,4-Dimethoxybenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone chemical structure, C13H15N5O3, CAS 307507-51-3
3,4-Dimethoxybenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone
CAS 307507-51-3C13H15N5O3
3-Nitro-4-methoxybenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone chemical structure, C12H12N6O4, CAS 469877-27-8
3-Nitro-4-methoxybenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone
CAS 469877-27-8C12H12N6O4
(E)-2-((2-(6-Methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazono)methyl)benzoic acid chemical structure, C12H11N5O3, CAS 468752-68-3
(E)-2-((2-(6-Methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazono)methyl)benzoic acid
CAS 468752-68-3C12H11N5O3
5-[(2E)-2-(4-Hydroxy-3-methoxybenzylidene)hydrazinyl]-6-methyl-1,2,4-triazin-3-ol chemical structure, C12H13N5O3, CAS 307506-65-6
5-[(2E)-2-(4-Hydroxy-3-methoxybenzylidene)hydrazinyl]-6-methyl-1,2,4-triazin-3-ol
CAS 307506-65-6C12H13N5O3
4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone chemical structure, C12H12N6O5, CAS 307507-56-8
4-Hydroxy-3-methoxy-5-nitrobenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone
CAS 307507-56-8C12H12N6O5
4-Hydroxy-3,5-dimethoxybenzaldehyde (3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone chemical structure, C12H13N5O4, CAS 468750-05-2
4-Hydroxy-3,5-dimethoxybenzaldehyde (3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone
CAS 468750-05-2C12H13N5O4