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Murcko scaffold

2,5-Piperidinedione scaffold

26 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
26
With full pages
7
Scaffold SMILES

O=C1CCC(=O)NC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Piperidinedione page
Murcko scaffold O=C1CCC(=O)NC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2,5-Piperidinedione chemical structure, C5H7NO2, CAS 52065-78-8
2,5-Piperidinedione
CAS 52065-78-8C5H7NO2
1,4,4-Trimethylpiperidine-2,5-dione chemical structure, C8H13NO2, CAS 2377033-55-9
1,4,4-Trimethylpiperidine-2,5-dione
CAS 2377033-55-9C8H13NO2
1-Methylpiperidine-2,5-dione chemical structure, C6H9NO2, CAS 408309-25-1
1-Methylpiperidine-2,5-dione
CAS 408309-25-1C6H9NO2
1-(2-Propen-1-yl)-2,5-piperidinedione chemical structure, C8H11NO2, CAS 564484-67-9
1-(2-Propen-1-yl)-2,5-piperidinedione
CAS 564484-67-9C8H11NO2
(S)-3,6-Dioxopiperidine-2-carboxylic acid chemical structure, C6H7NO4, CAS 2733623-78-2
(S)-3,6-Dioxopiperidine-2-carboxylic acid
CAS 2733623-78-2C6H7NO4
6,6-Dimethylpiperidine-2,5-dione chemical structure, C7H11NO2, CAS 1803612-31-8
6,6-Dimethylpiperidine-2,5-dione
CAS 1803612-31-8C7H11NO2
3,3-Dimethylpiperidine-2,5-dione chemical structure, C7H11NO2, CAS 2059987-11-8
3,3-Dimethylpiperidine-2,5-dione
CAS 2059987-11-8C7H11NO2
Piperidine-2,5-dione hydrochloride chemical structure, C5H8ClNO2, CAS 1956318-65-2
Piperidine-2,5-dione hydrochloride
CAS 1956318-65-2C5H8ClNO2
1,3,3-Trimethylpiperidine-2,5-dione chemical structure, C8H13NO2, CAS 2325969-61-5
1,3,3-Trimethylpiperidine-2,5-dione
CAS 2325969-61-5C8H13NO2
1-(Prop-2-yn-1-yl)piperidine-2,5-dione chemical structure, C8H9NO2, CAS 2247107-31-7
1-(Prop-2-yn-1-yl)piperidine-2,5-dione
CAS 2247107-31-7C8H9NO2
4,4-Dimethylpiperidine-2,5-dione chemical structure, C7H11NO2, CAS 2377033-27-5
4,4-Dimethylpiperidine-2,5-dione
CAS 2377033-27-5C7H11NO2
3-Methyl-3-(propan-2-yl)piperidine-2,5-dione chemical structure, C9H15NO2, CAS 2219407-99-3
3-Methyl-3-(propan-2-yl)piperidine-2,5-dione
CAS 2219407-99-3C9H15NO2
3-(Methanesulfonylmethyl)-3-methylpiperidine-2,5-dione chemical structure, C8H13NO4S, CAS 2219370-59-7
3-(Methanesulfonylmethyl)-3-methylpiperidine-2,5-dione
CAS 2219370-59-7C8H13NO4S
3-Ethyl-3-methylpiperidine-2,5-dione chemical structure, C8H13NO2, CAS 2219375-59-2
3-Ethyl-3-methylpiperidine-2,5-dione
CAS 2219375-59-2C8H13NO2
3-Methyl-3-propylpiperidine-2,5-dione chemical structure, C9H15NO2, CAS 2219408-68-9
3-Methyl-3-propylpiperidine-2,5-dione
CAS 2219408-68-9C9H15NO2
3-(Butan-2-yl)-3-methylpiperidine-2,5-dione chemical structure, C10H17NO2, CAS 2219370-66-6
3-(Butan-2-yl)-3-methylpiperidine-2,5-dione
CAS 2219370-66-6C10H17NO2
3-[(Dimethylamino)methyl]-3-methylpiperidine-2,5-dione chemical structure, C9H16N2O2, CAS 2219407-74-4
3-[(Dimethylamino)methyl]-3-methylpiperidine-2,5-dione
CAS 2219407-74-4C9H16N2O2
3-(3-Methoxypropyl)-3-methylpiperidine-2,5-dione chemical structure, C10H17NO3, CAS 2219372-19-5
3-(3-Methoxypropyl)-3-methylpiperidine-2,5-dione
CAS 2219372-19-5C10H17NO3
3-Butyl-3-(propan-2-yl)piperidine-2,5-dione chemical structure, C12H21NO2, CAS 2219408-41-8
3-Butyl-3-(propan-2-yl)piperidine-2,5-dione
CAS 2219408-41-8C12H21NO2
3,3-Diethylpiperidine-2,5-dione chemical structure, C9H15NO2, CAS 2219375-76-3
3,3-Diethylpiperidine-2,5-dione
CAS 2219375-76-3C9H15NO2
3-(3,3-Dimethylbutyl)-3-methylpiperidine-2,5-dione chemical structure, C12H21NO2, CAS 2219375-84-3
3-(3,3-Dimethylbutyl)-3-methylpiperidine-2,5-dione
CAS 2219375-84-3C12H21NO2
3-tert-Butyl-3-methylpiperidine-2,5-dione chemical structure, C10H17NO2, CAS 2219379-25-4
3-tert-Butyl-3-methylpiperidine-2,5-dione
CAS 2219379-25-4C10H17NO2
tert-Butyl N-methyl-N-[(3-methyl-2,5-dioxopiperidin-3-yl)methyl]carbamate chemical structure, C13H22N2O4, CAS 2219368-61-1
tert-Butyl N-methyl-N-[(3-methyl-2,5-dioxopiperidin-3-yl)methyl]carbamate
CAS 2219368-61-1C13H22N2O4
3-Ethyl-3-(2,2,2-trifluoroethyl)piperidine-2,5-dione chemical structure, C9H12F3NO2, CAS 2219368-97-3
3-Ethyl-3-(2,2,2-trifluoroethyl)piperidine-2,5-dione
CAS 2219368-97-3C9H12F3NO2