Murcko scaffold
Ring system with 3 rings and 20 atoms
28 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 28
- With full pages
- 1
Scaffold SMILES
O=C(COc1ccccc1)Nc1coc2ccccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 28 of 28 chemicals
![3-[[2-(4-Fluorophenoxy)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl ester chemical structure, C19H16FNO5, CAS 847406-63-7](/s/JJGFZJWPTMPRCJ-UHFFFAOYSA-N.svg)
3-[[2-(4-Fluorophenoxy)-1-oxoethyl]amino]-2-benzofurancarboxylic acid ethyl ester
CAS 847406-63-7C19H16FNO5
Ethyl 3-(2-(3-methoxyphenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-41-1C20H19NO6
3-(2-(2,4-Dichlorophenoxy)acetamido)benzofuran-2-carboxamide
CAS 477295-09-3C17H12Cl2N2O4
Ethyl 3-(2-phenoxyacetamido)benzofuran-2-carboxylate
CAS 477500-75-7C19H17NO5
3-(2-(4-Chlorophenoxy)acetamido)benzofuran-2-carboxamide
CAS 477294-63-6C17H13ClN2O4
3-(2-Phenoxyacetamido)benzofuran-2-carboxamide
CAS 477294-67-0C17H14N2O4
Ethyl 3-(2-(4-chlorophenoxy)acetamido)benzofuran-2-carboxylate
CAS 477500-78-0C19H16ClNO5
Ethyl 3-(2-(4-chlorophenoxy)-2-methylpropanamido)benzofuran-2-carboxylate
CAS 847405-99-6C21H20ClNO5
Ethyl 3-(2-(2-methoxyphenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-39-7C20H19NO6
Ethyl 3-(2-(4-methoxyphenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-44-4C20H19NO6
Ethyl 3-(2-(4-ethoxyphenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-47-7C21H21NO6
Ethyl 3-(2-(o-tolyloxy)acetamido)benzofuran-2-carboxylate
CAS 847406-50-2C20H19NO5
Ethyl 3-(2-(m-tolyloxy)acetamido)benzofuran-2-carboxylate
CAS 847406-53-5C20H19NO5
Ethyl 3-(2-(p-tolyloxy)acetamido)benzofuran-2-carboxylate
CAS 847406-56-8C20H19NO5
Ethyl 3-(2-(4-isopropylphenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-59-1C22H23NO5
Ethyl 3-(2-(2-fluorophenoxy)acetamido)benzofuran-2-carboxylate
CAS 847406-61-5C19H16FNO5
![3-[2-(2-Methoxyphenoxy)acetamido]-1-benzofuran-2-carboxamide chemical structure, C18H16N2O5, CAS 898373-64-3](/s/NQUWKWJDEVNBDQ-UHFFFAOYSA-N.svg)
3-[2-(2-Methoxyphenoxy)acetamido]-1-benzofuran-2-carboxamide
CAS 898373-64-3C18H16N2O5
![3-[2-(4-Methoxyphenoxy)acetamido]-1-benzofuran-2-carboxamide chemical structure, C18H16N2O5, CAS 898373-68-7](/s/LJITWIXHFNMREE-UHFFFAOYSA-N.svg)
3-[2-(4-Methoxyphenoxy)acetamido]-1-benzofuran-2-carboxamide
CAS 898373-68-7C18H16N2O5
3-(2-(4-Ethoxyphenoxy)acetamido)benzofuran-2-carboxamide
CAS 898373-70-1C19H18N2O5
3-(2-(o-Tolyloxy)acetamido)benzofuran-2-carboxamide
CAS 898373-72-3C18H16N2O4
3-(2-(m-Tolyloxy)acetamido)benzofuran-2-carboxamide
CAS 898373-74-5C18H16N2O4
3-(2-(p-Tolyloxy)acetamido)benzofuran-2-carboxamide
CAS 898373-76-7C18H16N2O4
3-(2-(4-Isopropylphenoxy)acetamido)benzofuran-2-carboxamide
CAS 898373-78-9C20H20N2O4
3-(2-(2-Fluorophenoxy)acetamido)benzofuran-2-carboxamide
CAS 898373-80-3C17H13FN2O4
- 3-(2-(4-Fluorophenoxy)acetamido)benzofuran-2-carboxamide898354-77-3C17H13FN2O4
- Ethyl 3-(2-(2,4-dichlorophenoxy)acetamido)benzofuran-2-carboxylate477501-11-4C19H15Cl2NO5
- Ethyl 3-(2-phenoxypropanamido)benzofuran-2-carboxylate847405-95-2C20H19NO5
- 3-(2-Phenoxypropanamido)benzofuran-2-carboxamide898373-58-5C18H16N2O4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc(CNCCc2c[nH]c3ccccc23)cc1](/scaffold/PRRZWJAGZHENJJ-UHFFFAOYSA-N/structure.svg)
c1ccc(CNCCc2c[nH]c3ccccc23)cc15 chemicals![Scaffold O=C(NCCc1c[nH]c2ccccc12)c1ccccc1](/scaffold/KTEDBFKQSUUOQJ-UHFFFAOYSA-N/structure.svg)
O=C(NCCc1c[nH]c2ccccc12)c1ccccc13 chemicals
O=C(Nc1ncccn1)NS(=O)(=O)c1cnc2ccccn122 chemicals
c1ccc(OCCCn2cnc3ccccc32)cc12 chemicals
O=C(NN=Cc1ccccc1)c1csc2c1CCCC22 chemicals
O=S(=O)(NN=Cc1cnc2ccccn12)c1ccccc11 chemical![Scaffold O=C1CCCC(CNCCc2c[nH]c3ccccc23)C1](/scaffold/FZMSQHVNZMVUEG-UHFFFAOYSA-N/structure.svg)
O=C1CCCC(CNCCc2c[nH]c3ccccc23)C11 chemical
O=C(OCC(=O)N1CCc2ccccc21)c1cccnc11 chemical![Scaffold O=C(NN=Cc1c[nH]c2ccccc12)c1ccccc1](/scaffold/GPZLLYBQEWHEKL-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1c[nH]c2ccccc12)c1ccccc11 chemical![Scaffold O=C(NN=Cc1ccccc1)c1c[nH]c2ccccc12](/scaffold/HDFBNYFWMWAGMI-UHFFFAOYSA-N/structure.svg)
O=C(NN=Cc1ccccc1)c1c[nH]c2ccccc121 chemical![Scaffold O=C(NCc1ccccc1)C(=O)c1c[nH]c2ccccc12](/scaffold/HWOWPGLTTSFLOQ-UHFFFAOYSA-N/structure.svg)
O=C(NCc1ccccc1)C(=O)c1c[nH]c2ccccc121 chemical![Scaffold O=C(C=Cc1c[nH]c2ccccc12)Nc1ccccc1](/scaffold/IPCJNZFDVCMNOB-UHFFFAOYSA-N/structure.svg)
O=C(C=Cc1c[nH]c2ccccc12)Nc1ccccc11 chemical