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Murcko scaffold

Ring system with 3 rings and 20 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1csc2c1CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1csc2c1CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

N'-(3-Fluorobenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C16H15FN2OS, CAS 444924-95-2
N'-(3-Fluorobenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 444924-95-2C16H15FN2OS
N-[(E)-(4-Chloro-3-nitrophenyl)methylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C16H14ClN3O3S, CAS 444926-06-1
N-[(E)-(4-Chloro-3-nitrophenyl)methylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 444926-06-1C16H14ClN3O3S
N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C20H25N3OS, CAS 444930-35-2
N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 444930-35-2C20H25N3OS
Methyl 4-[(E)-(4,5,6,7-tetrahydro-1-benzothiophene-3-carbonylhydrazinylidene)methyl]benzoate chemical structure, C18H18N2O3S, CAS 514843-35-7
Methyl 4-[(E)-(4,5,6,7-tetrahydro-1-benzothiophene-3-carbonylhydrazinylidene)methyl]benzoate
CAS 514843-35-7C18H18N2O3S
N'-(4-Methylbenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C17H18N2OS, CAS 444932-45-0
N'-(4-Methylbenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 444932-45-0C17H18N2OS
N'-(2-Fluorobenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C16H15FN2OS, CAS 445022-27-5
N'-(2-Fluorobenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 445022-27-5C16H15FN2OS
N'-[4-(Methylsulfanyl)benzylidene]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C17H18N2OS2, CAS 444924-26-9
N'-[4-(Methylsulfanyl)benzylidene]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 444924-26-9C17H18N2OS2
N'-(4-Hydroxy-3,5-dimethoxybenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C18H20N2O4S, CAS 445022-17-3
N'-(4-Hydroxy-3,5-dimethoxybenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 445022-17-3C18H20N2O4S
N'-(5-Bromo-2-hydroxybenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide chemical structure, C16H15BrN2O2S, CAS 515121-76-3
N'-(5-Bromo-2-hydroxybenzylidene)-4,5,6,7-tetrahydro-1-benzothiophene-3-carbohydrazide
CAS 515121-76-3C16H15BrN2O2S