Murcko scaffold
Ring system with 9 rings and 38 atoms
86 chemicals on CompoundList share this ring system.
- Rings
- 9
- Scaffold atoms
- 38
- Chemicals
- 86
- With full pages
- 17
Scaffold SMILES
C1=CC2CCC3Nc4ccc(C5CC6CCCN(CCc7c5[nH]c5ccccc75)C6)cc4C34CCN(C1)C24
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold C1=CC2CCC3Nc4ccc(C5CC6CCCN(CCc7c5[nH]c5ccccc75)C6)cc4C34CCN(C1)C24](/scaffold/IDKFHPRIUNPTCC-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 86 chemicals
Vincristine
CAS 57-22-7C46H56N4O10
Vinblastine
CAS 865-21-4C46H58N4O9
Vindesine
CAS 53643-48-4C43H55N5O7
Vindesine sulfate
CAS 59917-39-4C43H57N5O11S
Nitrogen mustard regimen with prednisone, procarbazine and vincristine
CAS 113803-47-7C84H113Cl3N8O16
Vinrosidine sulfate
CAS 18556-44-0C46H60N4O13S
Vinrosidine
CAS 15228-71-4C46H58N4O9
Desacetylvinblastine hydrazide
CAS 55383-37-4C43H56N6O7
RefChem:180416
CAS 123286-01-1C51H74N5O14PS
Leurosidine N'b-oxide
CAS 80374-74-9C46H58N4O10
4'-Deoxyvinblastine
CAS 20072-25-7C46H58N4O8
C95H115N5O26
CAS 123354-96-1C95H115N5O26
4-Desacetylvinblastine
C44H56N4O8
RefChem:1099275
CAS 19694-26-9C44H58N4O12S
Vincaleukoblastine sulfate
CAS 3085544-71-1C46H60N4O13S
(+)-Vinblastine
CAS 72401-36-6C46H58N4O9
Vincristine sulfate
CAS 2068-78-2C46H58N4O14S
4'-Deoxyvincaleukoblastine
CAS 57194-39-5C46H58N4O8
N-Desmethyl-N-allyloxymethylvinblastine
CAS 81879-44-9C49H62N4O10
N-beta-Hydroxyethylvindesine sulfate
CAS 64234-48-6C45H61N5O12S
Hydroxyethylvindesine
CAS 55324-79-3C45H59N5O8
4'-Deoxy vincristine
C46H56N4O9
![Methyl 12-ethyl-4-(17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl)-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid chemical structure, C44H56N4O12S, CAS 65120-24-3](/s/BNWZEKQOMCNOPS-UHFFFAOYSA-N.svg)
Methyl 12-ethyl-4-(17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl)-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acid
CAS 65120-24-3C44H56N4O12S
![Vincaleukoblastine, O4-deacetyl-3-de(methoxycarbonyl)-3-[[[1-(ethoxycarbonyl)-2-methylbutyl]amino]carbonyl]- chemical structure, C51H69N5O9](/s/QSTPFUDHVVIGCL-UHFFFAOYSA-N.svg)
Vincaleukoblastine, O4-deacetyl-3-de(methoxycarbonyl)-3-[[[1-(ethoxycarbonyl)-2-methylbutyl]amino]carbonyl]-
C51H69N5O9
- Vinblastine-N-methyl amide sulfate64448-88-0C46H61N5O12S
- Vincaleukoblastine, O(sup 4)-deacetyl-3-de(methoxycarbonyl)-3-(((1-(ethoxycarbonyl)-3-methylbutyl)amino)carbonyl)-, (3(R))-81571-25-7C51H69N5O9
- 72 suppliersVinblastine sulfate143-67-9C46H60N4O13S
- 17 suppliers(+)-Vincristine132142-73-5C46H56N4O10
- Methyl (1R,9R,10R,12R,19S)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, sulfuric acidC44H56N4O12S
- DesacetylvinblastineC44H56N4O8
- rel-(3aR,3a1R,4R,5S,5aR,10bR)-Methyl 4-acetoxy-3a-ethyl-9-((5S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizC46H60N4O13S
- Vinleucinol81571-28-0C51H69N5O9
- Vincaleukoblastine, 4a(2)-deoxy-, (4a(2)I+/-,18a(2)I+/-)-28808-73-3C46H58N4O8
- N-Desformyl-4-desacetyl Vincristine55324-83-9C43H54N4O8
- 4-Desacetyl vinblastineC44H56N4O8
- 4-Deacetylvinblastine3352-69-0C44H56N4O8
- Vinblastine impurity G55855-88-4C44H56N4O7
- Methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17R)-17-ethyl-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylateC46H56N4O9
- Vincristine EP impurity B sulfate68135-17-1C46H58N4O13S
- 1 suppliersVelban1212440-53-3C46H60N4O13S
- Vinepidine sulfate83200-11-7C46H58N4O13S
- Vinepidine68170-69-4C46H56N4O9
- ALB-109564 dihydrochloride1300114-12-8C47H62Cl2N4O9S
- Alb-109564854756-74-4C47H60N4O9S
- Vincristine-d3 sulfate1217854-24-4C46H58N4O14S
- 4-O-Deacetylvinblastine-3-oic acid60223-75-8C43H54N4O8
- 1-Demethylvincaleukoblastine18172-50-4C45H56N4O9
- 22-Oxovincaleukoblastine, compound with 5-oxo-L-proline (1:2)93963-75-8C56H70N6O16
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold C1=CC2CC(c3ccc4c(c3)C35CCN6CC=CC(CCC3N4)C65)c3[nH]c4ccccc4c3CCN(C1)C2](/scaffold/LXKBDYVWWVEMAJ-UHFFFAOYSA-N/structure.svg)