Murcko scaffold
3-(Phenylsulfanyl)pyrrolidine scaffold
58 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 58
- With full pages
- 4
Scaffold SMILES
c1ccc(SC2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 58 chemicals
Zofenoprilat
CAS 75176-37-3C15H19NO3S2
Zofenoprilat-d5
C15H19NO3S2
(4S)-4-(Phenylsulfanyl)-L-proline
CAS 81653-77-2C11H13NO2S
Zofenoprilat arginine
CAS 81872-09-5C21H33N5O5S2
L-Proline, 4-(phenylthio)-, trans-
CAS 144582-43-4C11H13NO2S
(2S,4S)-1-(tert-Butoxycarbonyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid
CAS 83623-88-5C16H21NO4S
![3-[(4-Chlorophenyl)sulfanyl]pyrrolidine chemical structure, C10H12ClNS, CAS 101768-31-4](/s/CZIVEYOBQCTLEO-UHFFFAOYSA-N.svg)
3-[(4-Chlorophenyl)sulfanyl]pyrrolidine
CAS 101768-31-4C10H12ClNS
![3-[(4-Methylphenyl)sulfanyl]pyrrolidine chemical structure, C11H15NS, CAS 101768-99-4](/s/YWZVTGOSHIRQOP-UHFFFAOYSA-N.svg)
3-[(4-Methylphenyl)sulfanyl]pyrrolidine
CAS 101768-99-4C11H15NS
Methyl 4-(phenylsulfanyl)pyrrolidine-2-carboxylate
CAS 1706431-44-8C12H15NO2S
3-(Phenylsulfanyl)pyrrolidine
CAS 1226416-13-2C10H13NS
Rel-(2R,4S)-1-((S)-3-mercapto-2-methylpropanoyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid
CAS 1329745-81-4C15H19NO3S2
Cis-4-Phenylthio-L-proline hydrochloride
CAS 105107-84-4C11H14ClNO2S
![(4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenyl-d5-thio)-L-proline chemical structure, C15H19NO3S2, CAS 1217716-12-5](/s/UQWLOWFDKAFKAP-QBORCZMVSA-N.svg)
(4S)-1-[(2S)-3-Mercapto-2-methyl-1-oxopropyl]-4-(phenyl-d5-thio)-L-proline
CAS 1217716-12-5C15H19NO3S2
(S)-tert-Butyl 3-((4-fluorophenyl)thio)pyrrolidine-1-carboxylate
CAS 1289584-88-8C15H20FNO2S
(R)-3-((4-Fluorophenyl)thio)pyrrolidine hydrochloride
CAS 1289584-92-4C10H13ClFNS
(S)-tert-Butyl 3-((4-chlorophenyl)thio)pyrrolidine-1-carboxylate
CAS 1289585-03-0C15H20ClNO2S
![3-[(2-Methoxyphenyl)sulfanyl]pyrrolidine chemical structure, C11H15NOS, CAS 1249974-78-4](/s/FXCGEPDSLSWIKM-UHFFFAOYSA-N.svg)
3-[(2-Methoxyphenyl)sulfanyl]pyrrolidine
CAS 1249974-78-4C11H15NOS
![3-[(4-Fluorophenyl)sulfanyl]pyrrolidine chemical structure, C10H12FNS, CAS 1249786-35-3](/s/ZDMRCFVGYKMWGE-UHFFFAOYSA-N.svg)
3-[(4-Fluorophenyl)sulfanyl]pyrrolidine
CAS 1249786-35-3C10H12FNS
![3-[(4-Methoxyphenyl)sulfanyl]pyrrolidine chemical structure, C11H15NOS, CAS 1250680-81-9](/s/FRIKEAYAMSNBRO-UHFFFAOYSA-N.svg)
3-[(4-Methoxyphenyl)sulfanyl]pyrrolidine
CAS 1250680-81-9C11H15NOS
3-(2,4-Difluorophenyl)sulfanylpyrrolidine
CAS 1248500-85-7C10H11F2NS
3-((4-Bromophenyl)sulfanyl)pyrrolidine
CAS 1250919-95-9C10H12BrNS
![3-[(3-Chlorophenyl)sulfanyl]pyrrolidine chemical structure, C10H12ClNS, CAS 1250219-60-3](/s/DNZDAGFWCBBVEH-UHFFFAOYSA-N.svg)
3-[(3-Chlorophenyl)sulfanyl]pyrrolidine
CAS 1250219-60-3C10H12ClNS
(S)-3-((4-Chlorophenyl)thio)pyrrolidine hydrochloride
CAS 1354018-01-1C10H13Cl2NS
(S)-3-((4-Fluorophenyl)thio)pyrrolidine hydrochloride
CAS 1353995-35-3C10H13ClFNS
- (R)-3-((4-Chlorophenyl)thio)pyrrolidine hydrochloride1354019-50-3C10H13Cl2NS
- (R)-tert-Butyl 3-((4-fluorophenyl)thio)pyrrolidine-1-carboxylate1289585-20-1C15H20FNO2S
- (R)-tert-Butyl 3-((4-chlorophenyl)thio)pyrrolidine-1-carboxylate1289585-33-6C15H20ClNO2S
- (S)-tert-Butyl 3-((2-methoxyphenyl)thio)pyrrolidine-1-carboxylate1354006-79-3C16H23NO3S
- (S)-3-((2,4-Dichlorophenyl)thio)pyrrolidine hydrochloride1354000-39-7C10H12Cl3NS
- (R)-3-((2-Methoxyphenyl)thio)pyrrolidine hydrochloride1417789-77-5C11H16ClNOS
- 3-(2,6-Dichloro-phenylsulfanyl)-pyrrolidine1706455-58-4C10H11Cl2NS
- 3-[(4-Fluorophenyl)sulfanyl]pyrrolidine hydrochloride1864072-84-3C10H13ClFNS
- 3-(Phenylsulfanyl)pyrrolidine hydrochloride1864054-02-3C10H14ClNS
- 3-[(4-Chlorophenyl)sulfanyl]pyrrolidine hydrochloride1864072-81-0C10H13Cl2NS
- 3-[(4-Methylphenyl)sulfanyl]pyrrolidine hydrochloride1864016-35-2C11H16ClNS
- 3-[(4-Bromophenyl)sulfanyl]pyrrolidine hydrochloride1864052-09-4C10H13BrClNS
- 3-[(2,6-Dichlorophenyl)sulfanyl]pyrrolidine hydrochloride1864054-12-5C10H12Cl3NS
- 3-[(4-Methoxyphenyl)sulfanyl]pyrrolidine hydrochloride1864062-29-2C11H16ClNOS
- 3-[(2-Methoxyphenyl)sulfanyl]pyrrolidine hydrochloride1864054-26-1C11H16ClNOS
- 3-[(3-Chlorophenyl)sulfanyl]pyrrolidine hydrochloride1803602-21-2C10H13Cl2NS
- 3-((2-Fluorophenyl)thio)pyrrolidine hydrochloride2097956-06-2C10H13ClFNS
- tert-Butyl (3R,4R)-3-hydroxy-4-(phenylsulfanyl)pyrrolidine-1-carboxylate2290726-74-6C15H21NO3S
- tert-Butyl (3R,4R)-3-[(4-aminophenyl)sulfanyl]-4-hydroxypyrrolidine-1-carboxylate2380993-85-9C15H22N2O3S
- tert-Butyl (3R,4R)-3-[(2-aminophenyl)sulfanyl]-4-hydroxypyrrolidine-1-carboxylate2381429-87-2C15H22N2O3S
- tert-Butyl (3R,4R)-3-[(4-bromophenyl)sulfanyl]-4-hydroxypyrrolidine-1-carboxylate2277129-49-2C15H20BrNO3S
- tert-Butyl (3R,4R)-3-[(4-chlorophenyl)sulfanyl]-4-hydroxypyrrolidine-1-carboxylate2290837-11-3C15H20ClNO3S
- tert-Butyl (3R,4R)-3-[(4-fluorophenyl)sulfanyl]-4-hydroxypyrrolidine-1-carboxylate2277321-40-9C15H20FNO3S
- tert-Butyl (3R,4R)-3-hydroxy-4-[(4-hydroxyphenyl)sulfanyl]pyrrolidine-1-carboxylate2290680-27-0C15H21NO4S
Related scaffolds
Same ring framework with different atoms or bond orders
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O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
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O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
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