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Murcko scaffold

Ring system with 3 rings and 25 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
13
With full pages
5
Scaffold SMILES

O=C(NCc1nnc(SCCOc2ccccc2)[nH]1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1nnc(SCCOc2ccccc2)[nH]1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

2-Bromo-N-[[4-ethyl-5-[2-(4-methoxyphenoxy)ethylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C21H23BrN4O3S, CAS 767324-77-6
2-Bromo-N-[[4-ethyl-5-[2-(4-methoxyphenoxy)ethylsulfanyl]-1,2,4-triazol-3-yl]methyl]benzamide
CAS 767324-77-6C21H23BrN4O3S
2-Fluoro-N-[[5-(2-phenoxyethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C21H21FN4O2S, CAS 823833-44-9
2-Fluoro-N-[[5-(2-phenoxyethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 823833-44-9C21H21FN4O2S
3,4-Dichloro-N-[[4-methyl-5-(2-phenoxyethylsulfanyl)-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C19H18Cl2N4O2S, CAS 823836-89-1
3,4-Dichloro-N-[[4-methyl-5-(2-phenoxyethylsulfanyl)-1,2,4-triazol-3-yl]methyl]benzamide
CAS 823836-89-1C19H18Cl2N4O2S
2-Bromo-N-[[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C20H21BrN4O3S, CAS 717894-33-2
2-Bromo-N-[[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-methyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 717894-33-2C20H21BrN4O3S
3,4-Dichloro-N-[[5-(2-phenoxyethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C21H20Cl2N4O2S, CAS 792943-58-9
3,4-Dichloro-N-[[5-(2-phenoxyethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methyl]benzamide
CAS 792943-58-9C21H20Cl2N4O2S
3-Methyl-N-[[4-methyl-5-(2-phenoxyethylsulfanyl)-1,2,4-triazol-3-yl]methyl]benzamide chemical structure, C20H22N4O2S, CAS 838842-16-3
3-Methyl-N-[[4-methyl-5-(2-phenoxyethylsulfanyl)-1,2,4-triazol-3-yl]methyl]benzamide
CAS 838842-16-3C20H22N4O2S
N-[2-Hydroxy-1-[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]-4-methoxybenzamide chemical structure, C24H28N4O5S, CAS 767324-91-4
N-[2-Hydroxy-1-[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]-4-methoxybenzamide
CAS 767324-91-4C24H28N4O5S
4-Methoxy-N-[1-[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]-2-methylpropyl]benzamide chemical structure, C26H32N4O4S, CAS 767324-92-5
4-Methoxy-N-[1-[5-[2-(4-methoxyphenoxy)ethylsulfanyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]-2-methylpropyl]benzamide
CAS 767324-92-5C26H32N4O4S
2-Bromo-N-(1-{4-methyl-5-[(2-phenoxyethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}ethyl)benzamide chemical structure, C20H21BrN4O2S, CAS 823836-86-8
2-Bromo-N-(1-{4-methyl-5-[(2-phenoxyethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}ethyl)benzamide
CAS 823836-86-8C20H21BrN4O2S
N-(2-Methyl-1-{4-methyl-5-[(2-phenoxyethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}propyl)benzamide chemical structure, C22H26N4O2S, CAS 823837-17-8
N-(2-Methyl-1-{4-methyl-5-[(2-phenoxyethyl)sulfanyl]-4H-1,2,4-triazol-3-yl}propyl)benzamide
CAS 823837-17-8C22H26N4O2S
N-(1-{5-[(2-Phenoxyethyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)benzamide chemical structure, C22H24N4O2S, CAS 823837-40-7
N-(1-{5-[(2-Phenoxyethyl)sulfanyl]-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl}ethyl)benzamide
CAS 823837-40-7C22H24N4O2S
N-[1-(4-Ethyl-5-{[2-(4-methoxyphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)-2-hydroxyethyl]-4-methoxybenzamide chemical structure, C23H28N4O5S, CAS 767324-90-3
N-[1-(4-Ethyl-5-{[2-(4-methoxyphenoxy)ethyl]sulfanyl}-4H-1,2,4-triazol-3-yl)-2-hydroxyethyl]-4-methoxybenzamide
CAS 767324-90-3C23H28N4O5S
4-Methoxy-N-{1-[5-{[2-(4-methoxyphenoxy)ethyl]sulfanyl}-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]ethyl}benzamide chemical structure, C24H28N4O4S, CAS 767324-81-2
4-Methoxy-N-{1-[5-{[2-(4-methoxyphenoxy)ethyl]sulfanyl}-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]ethyl}benzamide
CAS 767324-81-2C24H28N4O4S