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Murcko scaffold

Ring system with 3 rings and 26 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
14
With full pages
5
Scaffold SMILES

O=C(Cn1cc(C(=O)NCCc2ccccc2)nn1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1cc(C(=O)NCCc2ccccc2)nn1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

5-Amino-1-{2-[(2-methoxyphenyl)amino]-2-oxoethyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C20H22N6O3, CAS 865655-73-8
5-Amino-1-{2-[(2-methoxyphenyl)amino]-2-oxoethyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 865655-73-8C20H22N6O3
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-[2-(2-methoxyanilino)-2-oxoethyl]triazole-4-carboxamide chemical structure, C22H26N6O5, CAS 865655-74-9
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-[2-(2-methoxyanilino)-2-oxoethyl]triazole-4-carboxamide
CAS 865655-74-9C22H26N6O5
5-Amino-1-(2-anilino-2-oxoethyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-1,2,3-triazole-4-carboxamide chemical structure, C21H24N6O4, CAS 901017-83-2
5-Amino-1-(2-anilino-2-oxoethyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-1H-1,2,3-triazole-4-carboxamide
CAS 901017-83-2C21H24N6O4
5-Amino-1-{[(2,3-dimethylphenyl)carbamoyl]methyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C21H24N6O2, CAS 895651-71-5
5-Amino-1-{[(2,3-dimethylphenyl)carbamoyl]methyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 895651-71-5C21H24N6O2
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(2,6-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C23H28N6O4, CAS 887214-14-4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(2,6-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS 887214-14-4C23H28N6O4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(2,3-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C23H28N6O4, CAS 887214-17-7
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(2,3-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS 887214-17-7C23H28N6O4
5-Amino-N-(3,4-dimethoxyphenethyl)-1-(2-((2-ethylphenyl)amino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C23H28N6O4, CAS 887214-20-2
5-Amino-N-(3,4-dimethoxyphenethyl)-1-(2-((2-ethylphenyl)amino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 887214-20-2C23H28N6O4
5-Amino-N-(3,4-dimethoxyphenethyl)-1-(2-((4-ethylphenyl)amino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C23H28N6O4, CAS 887214-23-5
5-Amino-N-(3,4-dimethoxyphenethyl)-1-(2-((4-ethylphenyl)amino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 887214-23-5C23H28N6O4
5-Amino-N-(3,4-diethoxyphenethyl)-1-(2-(mesitylamino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C26H34N6O4, CAS 887221-01-4
5-Amino-N-(3,4-diethoxyphenethyl)-1-(2-(mesitylamino)-2-oxoethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 887221-01-4C26H34N6O4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{2-[(2,4-dimethylphenyl)amino]-2-oxoethyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C23H28N6O4, CAS 887221-03-6
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{2-[(2,4-dimethylphenyl)amino]-2-oxoethyl}-1H-1,2,3-triazole-4-carboxamide
CAS 887221-03-6C23H28N6O4
5-Amino-N-[2-(3,4-diethoxyphenyl)ethyl]-1-{[(2,5-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C25H32N6O4, CAS 901007-95-2
5-Amino-N-[2-(3,4-diethoxyphenyl)ethyl]-1-{[(2,5-dimethylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS 901007-95-2C25H32N6O4
5-Amino-1-{[(3-methylphenyl)carbamoyl]methyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide chemical structure, C20H22N6O2, CAS 901019-07-6
5-Amino-1-{[(3-methylphenyl)carbamoyl]methyl}-N-(2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide
CAS 901019-07-6C20H22N6O2
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(3-methylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C22H26N6O4, CAS 901045-55-4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{[(3-methylphenyl)carbamoyl]methyl}-1H-1,2,3-triazole-4-carboxamide
CAS 901045-55-4C22H26N6O4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{2-[(2-fluorophenyl)amino]-2-oxoethyl}-1H-1,2,3-triazole-4-carboxamide chemical structure, C21H23FN6O4, CAS 1291834-06-4
5-Amino-N-[2-(3,4-dimethoxyphenyl)ethyl]-1-{2-[(2-fluorophenyl)amino]-2-oxoethyl}-1H-1,2,3-triazole-4-carboxamide
CAS 1291834-06-4C21H23FN6O4