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Murcko scaffold

Ring system with 3 rings and 26 atoms

26 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
26
With full pages
4
Scaffold SMILES

O=C(Cc1csc(NC(=O)Nc2ccccc2)n1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1csc(NC(=O)Nc2ccccc2)n1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-[2-[(2-Methoxyphenyl)carbamoylamino]thiazol-4-yl]-N-p-anisyl-acetamide chemical structure, C21H22N4O4S, CAS 897621-88-4
2-[2-[(2-Methoxyphenyl)carbamoylamino]thiazol-4-yl]-N-p-anisyl-acetamide
CAS 897621-88-4C21H22N4O4S
N-(2-Methoxybenzyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O3S, CAS 1005305-11-2
N-(2-Methoxybenzyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 1005305-11-2C21H22N4O3S
N-(1-Phenylethyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O2S, CAS 1005299-47-7
N-(1-Phenylethyl)-2-(2-(3-(p-tolyl)ureido)thiazol-4-yl)acetamide
CAS 1005299-47-7C21H22N4O2S
N-Benzyl-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H20N4O2S, CAS 921484-58-4
N-Benzyl-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921484-58-4C20H20N4O2S
N-(2-Chlorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H19ClN4O2S, CAS 921499-60-7
N-(2-Chlorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921499-60-7C20H19ClN4O2S
N-(4-Fluorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H19FN4O2S, CAS 921466-27-5
N-(4-Fluorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921466-27-5C20H19FN4O2S
N-(4-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O3S, CAS 921484-60-8
N-(4-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921484-60-8C21H22N4O3S
N-(2-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O3S, CAS 921482-19-1
N-(2-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921482-19-1C21H22N4O3S
N-(4-Methylbenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O2S, CAS 921499-63-0
N-(4-Methylbenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921499-63-0C21H22N4O2S
N-(4-Chlorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H19ClN4O2S, CAS 921499-66-3
N-(4-Chlorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921499-66-3C20H19ClN4O2S
N-(3-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O3S, CAS 921473-70-3
N-(3-Methoxybenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921473-70-3C21H22N4O3S
N-(2,6-Difluorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H18F2N4O2S, CAS 921485-24-7
N-(2,6-Difluorobenzyl)-2-(2-(3-(m-tolyl)ureido)thiazol-4-yl)acetamide
CAS 921485-24-7C20H18F2N4O2S
2-(2-(3-(4-Chlorophenyl)ureido)thiazol-4-yl)-N-(4-fluorobenzyl)acetamide chemical structure, C19H16ClFN4O2S, CAS 921467-88-1
2-(2-(3-(4-Chlorophenyl)ureido)thiazol-4-yl)-N-(4-fluorobenzyl)acetamide
CAS 921467-88-1C19H16ClFN4O2S
2-(2-(3-(3-Chlorophenyl)ureido)thiazol-4-yl)-N-(2-methoxybenzyl)acetamide chemical structure, C20H19ClN4O3S, CAS 897621-18-0
2-(2-(3-(3-Chlorophenyl)ureido)thiazol-4-yl)-N-(2-methoxybenzyl)acetamide
CAS 897621-18-0C20H19ClN4O3S
2-(2-(3-(3-Chlorophenyl)ureido)thiazol-4-yl)-N-(3-methoxybenzyl)acetamide chemical structure, C20H19ClN4O3S, CAS 897621-58-8
2-(2-(3-(3-Chlorophenyl)ureido)thiazol-4-yl)-N-(3-methoxybenzyl)acetamide
CAS 897621-58-8C20H19ClN4O3S
N-(4-Fluorobenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H19FN4O3S, CAS 897621-86-2
N-(4-Fluorobenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
CAS 897621-86-2C20H19FN4O3S
N-(2-Methoxybenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O4S, CAS 897621-90-8
N-(2-Methoxybenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
CAS 897621-90-8C21H22N4O4S
N-(3-Methoxybenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide chemical structure, C21H22N4O4S, CAS 897614-08-3
N-(3-Methoxybenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
CAS 897614-08-3C21H22N4O4S
N-(2,6-Difluorobenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide chemical structure, C20H18F2N4O3S, CAS 897614-09-4
N-(2,6-Difluorobenzyl)-2-(2-(3-(2-methoxyphenyl)ureido)thiazol-4-yl)acetamide
CAS 897614-09-4C20H18F2N4O3S
N-Benzyl-2-(2-{[(4-methylphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide chemical structure, C20H20N4O2S, CAS 946224-59-5
N-Benzyl-2-(2-{[(4-methylphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide
CAS 946224-59-5C20H20N4O2S
2-(2-{[(4-Chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-[(2-chlorophenyl)methyl]acetamide chemical structure, C19H16Cl2N4O2S, CAS 946224-69-7
2-(2-{[(4-Chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)-N-[(2-chlorophenyl)methyl]acetamide
CAS 946224-69-7C19H16Cl2N4O2S
N-Benzyl-2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide chemical structure, C19H17ClN4O2S, CAS 946250-75-5
N-Benzyl-2-(2-{[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide
CAS 946250-75-5C19H17ClN4O2S
N-(2-Chlorobenzyl)-2-(2-(3-(3-chlorophenyl)ureido)thiazol-4-yl)acetamide chemical structure, C19H16Cl2N4O2S, CAS 946326-33-6
N-(2-Chlorobenzyl)-2-(2-(3-(3-chlorophenyl)ureido)thiazol-4-yl)acetamide
CAS 946326-33-6C19H16Cl2N4O2S
N-[(4-Chlorophenyl)methyl]-2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide chemical structure, C20H19ClN4O3S, CAS 946326-93-8
N-[(4-Chlorophenyl)methyl]-2-(2-{[(2-methoxyphenyl)carbamoyl]amino}-1,3-thiazol-4-yl)acetamide
CAS 946326-93-8C20H19ClN4O3S