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Murcko scaffold

5-(Phenoxymethyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
11
With full pages
7
Scaffold SMILES

O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-(Phenoxymethyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide page
Murcko scaffold O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

5-[(4-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C16H14N2O3S, CAS 801226-71-1
5-[(4-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 801226-71-1C16H14N2O3S
5-[(4-Fluorophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11FN2O3S, CAS 352693-14-2
5-[(4-Fluorophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 352693-14-2C15H11FN2O3S
5-[(4-Methyl-2-nitrophenoxy)methyl]-N-(5-methyl-1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C17H15N3O5S, CAS 444930-92-1
5-[(4-Methyl-2-nitrophenoxy)methyl]-N-(5-methyl-1,3-thiazol-2-yl)furan-2-carboxamide
CAS 444930-92-1C17H15N3O5S
5-[(2-Bromophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11BrN2O3S, CAS 438530-80-4
5-[(2-Bromophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 438530-80-4C15H11BrN2O3S
5-((2,4-Dichlorophenoxy)methyl)-N-(4-methylthiazol-2-yl)furan-2-carboxamide chemical structure, C16H12Cl2N2O3S, CAS 444114-90-3
5-((2,4-Dichlorophenoxy)methyl)-N-(4-methylthiazol-2-yl)furan-2-carboxamide
CAS 444114-90-3C16H12Cl2N2O3S
5-(Phenoxymethyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H12N2O3S, CAS 826997-34-6
5-(Phenoxymethyl)-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 826997-34-6C15H12N2O3S
N-(4-Methyl-1,3-thiazol-2-yl)-5-(phenoxymethyl)furan-2-carboxamide chemical structure, C16H14N2O3S, CAS 853726-08-6
N-(4-Methyl-1,3-thiazol-2-yl)-5-(phenoxymethyl)furan-2-carboxamide
CAS 853726-08-6C16H14N2O3S
5-[(2-Nitrophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C15H11N3O5S, CAS 515847-90-2
5-[(2-Nitrophenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 515847-90-2C15H11N3O5S
5-[(2-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C16H14N2O3S, CAS 878716-41-7
5-[(2-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 878716-41-7C16H14N2O3S
5-[(3-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide chemical structure, C16H14N2O3S, CAS 878716-43-9
5-[(3-Methylphenoxy)methyl]-N-(1,3-thiazol-2-yl)furan-2-carboxamide
CAS 878716-43-9C16H14N2O3S
5-[(3-Chlorophenoxy)methyl]-N-(4-methyl-2-thiazolyl)-2-furancarboxamide chemical structure, C16H13ClN2O3S, CAS 1426576-18-2
5-[(3-Chlorophenoxy)methyl]-N-(4-methyl-2-thiazolyl)-2-furancarboxamide
CAS 1426576-18-2C16H13ClN2O3S